Studies on Peptides. CXXVII. Synthesis of a Tripentacontapeptide with Epidermal Growth Factor Activity
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概要
- 論文の詳細を見る
The tripentacontapeptide corresponding to the entire linear sequence of epidermal growth factor was synthesized by assembling 15 peptide fragments and one His residue (position 22), followed by deprotection with trifluoromethanesulfonic acid-thioanisole in trifluoroacetic acid. The deprotected peptide was subjected to air-oxidation. After purification by ion-exchange chromatography on diethyl aminoethyl cellulose followed by high performance liquid chromatography, a peptide with powerful anti-gastric activity was obtained.
- 公益社団法人日本薬学会の論文
- 1985-01-25
著者
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藤井 信孝
Faculty of Pharmaceutical Sciences, Kyoto University
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矢島 治明
Faculty of Pharmaceutical Sciences, Kyoto University
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水田 和彦
First Department Of Internal Medicine Faculty Of Medicine:kyoto University
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赤路 健一
Faculty of Pharmaceutical Sciences
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矢島 治明
京都大学
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矢島 治明
京大・薬
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藤井 信孝
京大 薬
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矢島 治明
Faculty Of Pharmaceutical Sciences Kyoto University
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林 恭三
Gifu College of Pharmacy
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水田 和彦
1st Internal Medicine, School of Medicine, Kyoto University
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青野 充
1st Internal Medicine, School of Medicine, Kyoto University
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森賀 本幸
1st Internal Medicine, School of Medicine, Kyoto University
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赤路 健一
Faculty Of Pharmaceutical Sciences Kyoto University
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