Studies on Peptides. LXXVI. Synthesis of Kassinin, a New Frog Skin Peptide
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概要
- 論文の詳細を見る
Kassinin, a dodecapeptide amide isolated by Erspamer et al. from the skin of Kassina senegalensis, was synthesized by deprotection of Z (OMe)-Asp (OBzl)-Val-Pro-Lys (Z)-Ser-Asp (OBzl)-Gln-Phe-Val-Gly-Leu-Met (O)-NH_2 with methanesulphonic acid, followed by reduction of the Met (O) residue to Met with 2-mercaptoethanol. The contractile activity of synthetic kassinin in isolated guinea-pig ileum was 0.4 of that of synthetic substance P.
- 社団法人日本薬学会の論文
- 1978-04-25
著者
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仲田 義啓
広島大学大学院 医歯薬学総合研究科 薬効解析科学
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藤井 信孝
Faculty of Pharmaceutical Sciences, Kyoto University
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小川 博
Faculty Of Pharmaceutical Sciences Kyoto University
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佐々木 敬
Research Institute Daiichi Seiyaku Co. Ltd.
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仲田 義啓
Institute of Pharmaceutical Sciences, Hiroshima University
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瀬川 富郎
Faculty Of Pharmaceutical Sciences School Of Medicine Hiroshima University
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