Studies on Peptides. XLVIII. Application of the Trifluoromethanesulphonic Acid Procedure to the Synthesis of Tuftsin

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概要

• 論文の詳細を見る

• Trifluoromethanesulphonic acid removed all protecting groups from Z-Thr-Lys (Z)-Pro-Arg (Tos)-OH to give the phagocytosis-stimulating tetrapeptide, H-Thr-Lys-Pro-Arg-OH, named tuftsin. To this synthesis, the 5-chloro-8-quinolyl ester procedure was applied. With this connection, a number of analogous active esters was prepared.

• 社団法人日本薬学会の論文
• 1975-02-25

著者

• 藤井 信孝

  Faculty of Pharmaceutical Sciences, Kyoto University

• 小川 博

  Faculty Of Pharmaceutical Sciences Kyoto University

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