Studies on Peptides. XCIV. Synthesis and Activity of Kyotorphin and Its Analogs

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概要

• 論文の詳細を見る

• A dipeptide named kyotorphin, H-Tyr-Arg-OH, and its retro isomer were synthesized using N^G-mesitylene-2-sulfonylarginine. Two corresponding stereoisomers containing D-Arg were also synthesized. Among these, H-Tyr-D-Arg-OH was found to possess an analgesic effect 6 times higher than that of the corresponding L-isomer.

• 社団法人日本薬学会の論文
• 1980-06-25

著者

• 矢島 治明

  Faculty of Pharmaceutical Sciences, Kyoto University

• 小川 博

  Faculty Of Pharmaceutical Sciences Kyoto University

• 高木 博司

  京都大学薬学部

• 高木 博司

  Faculty Of Pharmaceutical Sciences Kyoto University

• 植田 弘師

  Faculty of Pharmaceutical Sciences, Kyoto University

• 植田 弘師

  長崎大学薬学部分子薬理学分野

• 植田 弘師

  長崎大学大学院医歯薬学総合研究科分子薬理学分野

• 植田 弘師

  京都大学薬学部薬理

• 矢島 治明

  Faculty Of Pharmaceutical Sciences Kyoto University

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