Studies on Peptides. LXXX. N^G-Mesitylene-2-sulfonylarginine
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概要
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N^G-mesitylene-2-sulfonylarginine was prepared. This protecting group was found to be quantitatively cleaved by hydrogen fluoride, methanesulfonic acid or trifluoromethanesulfonic acid and partially by hydrogen bromide in acetic acid. As a side reaction, partial mesitylenesulfonylation of the phenolic group of tyrosine was noted. However this side reaction could be suppressed by cation scavengers, anisole-thioanisole-cresol (o) (1 : 1 : 1), in less than 4%.
- 社団法人日本薬学会の論文
- 1978-12-25
著者
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西村 紀
Chemical Research Laboratories Central Research Division Takeda Chemical Industries Ltd.
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矢島 治明
Faculty of Pharmaceutical Sciences, Kyoto University
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藤野 政彦
Pharmaceutical Research Division Takeda Chemical Industries Ltd.
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藤野 政彦
武田薬品工業
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武山 正治
Department of Clinical Pharmacy, Oita Medical University
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藤野 政彦
Faculty of Pharmaceutical Sciences, Kyoto University
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藤野 政彦
武田薬品中央研
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武山 正治
Faculty of Pharmaceutical Sciences, Kyoto University
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金木 潤
Faculty of Pharmaceutical Sciences, Kyoto University
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西村 紀
Faculty of Pharmaceutical Sciences, Kyoto University
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武山 正治
Department Of Clinical Pharmacy Oita Medical University
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矢島 治明
Faculty Of Pharmaceutical Sciences Kyoto University
関連論文
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