p-Methoxybenzenesulfonyl as a Protecting Group of Guanidino Function in Peptide Synthesis

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概要

• 論文の詳細を見る

• The p-methoxybenzenesulfonyl (MBS) group was used to protect the ω-guanidino function in arginine and was found to be more easily and completely removed by treatment with methanesulfonic acid and borontristrifluoroacetate (BTFA) than the p-toluene-sulfonyl group. In order to evaluate the usefulness of this new protecting group in peptide synthesis, bradykinin and tuftsin were prepared by using the MBS group.

• 社団法人日本薬学会の論文
• 1976-07-25

著者

• 西村 紀

  Chemical Research Laboratories Central Research Division Takeda Chemical Industries Ltd.

• 藤野 政彦

  Chemistry Laboratories Central Research Division Takeda Chemical Industries Ltd.

• 藤野 政彦

  武田薬品中央研

• 西村 紀

  Medical Research Laboratory, Takeda Chemical Ind. Ltd.

• 藤野 政彦

  Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.

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