A New Procedure for the Pentachlorophenylation of N-Protected Amino Acids
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概要
- 論文の詳細を見る
The pentachlorophenyl trichloroacetate and dichloroacetate which were known as a soil sterilizer or a plant growth regulator, were subjected to the ester-exchange reaction with trialkylammonium salts of acylamino acids, and it has been found that they are excellent reagents for the preparation of the pentachlorophenyl active esters of acylamino acids which are known as intermediates in peptide synthesis. Some acylpeptide esters were also synthesized by the direct method utilizing these reagent, thus, the peptide derivatives were obtained in excellent yields and satisfactory purities.
- 公益社団法人日本薬学会の論文
- 1968-05-25
著者
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藤野 政彦
Chemistry Laboratories Central Research Division Takeda Chemical Industries Ltd.
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畑中 千年
Chemical Research Laboratories, Research and Developmemt Division, Takeda Chemical Industries, Ltd.
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畑中 千年
Research and Development Division, Takeda Chemical Industries, Ltd
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畑中 千年
Research And Development Division Takeda Chemical Industries Ltd
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