Isobornyloxycarbonyl Function, a New Convenient Amino-Protecting Group in Peptide Synthesis. II. Synthesis of Bradykinin
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概要
- 論文の詳細を見る
Bradykinin, a nonapeptide local tissue hormone, was synthesized by the use of the isobornyloxycarbonyl (IBOC-)-protecting group for the temporary protection of the all amino groups of the intermediary peptides. During the synthesis of bradykinin, no complication occurred in the processes involving the introduction and removal of the IBOC-group, and the final synthetic hormone showed up to possess the full biological activity and appeared to be pure by chemical criterions.
- 公益社団法人日本薬学会の論文
- 1972-05-25
著者
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藤野 政彦
Chemistry Laboratories Central Research Division Takeda Chemical Industries Ltd.
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品川 進
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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