Selective Transport of the Salts of Amino Acid Esters through an Organic Liquid Membrane with Antamanide as a Carrier

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概要

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• Antamanide was prepared by the 9-fluorenylmethyloxycarbonyl (Fmoc)-based solid-phase method, and the transport of L-Phe-OMe and L-Leu-OMe through an organic liquid membrane mediated by the synthetic antamanide was examined. It was found that antamanide has an ability to transport L-Phe-OMe・HCl twice as efficiently as L-Leu-OMe・HCl. Affinity between the phenyl groups present in both the host and guest may be responsible for the difference.

• 社団法人日本薬学会の論文
• 1988-08-25

著者

• 大高 章

  Faculty of Pharmaceutical Sciences, Kyoto University

• 矢島 治明

  Faculty of Pharmaceutical Sciences, Kyoto University

• 大高 章

  徳島大学大学院ヘルスバイオサイエンス研究部

• 大高 章

  京都大学 薬

• 片岡 裕美

  Faculty Of Pharmaceutical Sciences Mukogawa University

• 加多木 豊史

  Faculty of Pharmaceutical Sciences, Mukogawa Women's University

• 大高 章

  京大 大学院薬学研究科

• 矢島 治明

  京都大学

• 矢島 治明

  京大・薬

• 矢島 治明

  Faculty Of Pharmaceutical Sciences Kyoto University

• 加多木 豊史

  Faculty Of Pharmaceutical Science Mukogawa University

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