Studies on Peptides. CXXIV. Solution Synthesis of the Hentetracontapeptide Amide Corresponding to the Entire Amino Acid Sequence of Human Corticotropin Releasing Factor (hCRF)
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概要
- 論文の詳細を見る
The hentetracontapeptide amide corresponding to the entire amino acid sequence of human corticotropin releasing factor (hCRF), deduced from the complementary deoxyribonucleic acid (cDNA) sequence analysis, was synthesized by assembling nine peptide fragments in solution followed by deprotection with 1 M trifluoromethanesulfonic acid-thioanisole (molar ratio 1 : 1) in trifluoroacetic acid. The synthetic peptide significantly elevated the immunoreactive corticotropin level in rat plasma.
- 公益社団法人日本薬学会の論文
- 1984-12-25
著者
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藤井 信孝
Faculty of Pharmaceutical Sciences, Kyoto University
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矢島 治明
Faculty of Pharmaceutical Sciences, Kyoto University
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吉武 彬
Institute For Biological Sciences Sumitomo Chemical Co. Ltd.
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野水 基義
Faculty of Pharmaceutical Sciences
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赤路 健一
Faculty of Pharmaceutical Sciences
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庄野 文章
Institute For Biological Sciences Sumitomo Chemical Co. Ltd.
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庄野 文章
住友化学工業
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片倉 晋一
Faculty of Pharmaceutical Sciences, Kyoto University
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野水 基義
Faculty Of Pharmaceutical Sciences Kyoto University
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矢島 治明
京都大学
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片倉 晋一
Research Institute, Daiichi Pharmaceutical Co., Ltd.,
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矢島 治明
京大・薬
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藤井 信孝
京大 薬
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井村 裕夫
the 2nd Internal Medicine, Faculty of Medicine, Kyoto University
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渡辺 和英
Faculty of Pharmaceutical Sciences, Kyoto University
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霜倉 正徳
Faculty of Pharmaceutical Sciences, Kyoto University
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津田 正文
Institute for Biological Sciences, Sumitomo Chemical Co., Ltd.
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井村 裕夫
School of Medicine, Kyoto University
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津田 正文
Research laboratories, Sumitomo Pharmaceuticals Co., Ltd.,
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矢島 治明
Faculty Of Pharmaceutical Sciences Kyoto University
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霜倉 正徳
Department of Medicinal Chemistry, Kyoto Pharmaceutical University
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井村 裕夫
The 2nd Internal Medicine Faculty Of Medicine Kyoto University
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片倉 晋一
Research Institute Daiichi Pharmaceutical Co. Ltd.
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赤路 健一
Faculty Of Pharmaceutical Sciences Kyoto University
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霜倉 正徳
Department Of Medicinal Chemistry Kyoto Pharmaceutical University
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津田 正文
Research Laboratories Sumitomo Pharmaceuticals Co. Ltd.
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