Studies on Peptides. CLXV. : Combination of a New Amide-Precursor Reagent and Trimethylsilyl Bromide Deprotection for the 9-Fluorenylmenthyloxycarbonyl-Based Solid-Phase Synthesis of chicken Antral Peptide

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概要

• 論文の詳細を見る

• A 36-residue peptide amide corresponding to the entire amino acid sequence of chicken antral peptide was synthesized by the 9-fluorenylmethyloxycarbonyl (Fmoc)-based solid-phase synthesis, for which a new amide precursor reagent, 3-(α-Fmoc-amino-4-methoxybenzyl)-4-methoxyphenyl-propionic acid, was employed in combination with thioanisole-mediated trimethylsilyl bromide deprotection. A homogeneous standard sample prepared by the solution-phase method was used to check the effectiveness of the purification step.

• 公益社団法人日本薬学会の論文
• 1988-12-25

著者

• 藤井 信孝

  京都大学薬学部

• 藤井 信孝

  Faculty of Pharmaceutical Sciences, Kyoto University

• 矢島 治明

  Faculty of Pharmaceutical Sciences, Kyoto University

• 船越 奨

  Faculty of Pharmaceutical Sciences

• 矢島 治明

  京都大学

• 船越 奨

  Faculty Of Pharmaceutical Sciences Kyoto University

• 矢島 治明

  京大・薬

• 藤井 信孝

  京大 薬

• 郭 莉莉

  Faculty Of Pharmaceutical Sciences Kyoto University

• 矢島 治明

  Faculty Of Pharmaceutical Sciences Kyoto University

• 藤井 信孝

  京都大学

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