Studies on Peptides. CXXVI. Synthesis of the Protected Tetracosapeptide Corresponding to Positions 30-53 of Mouse Epidermal Growth Factor (EGF)

スポンサーリンク

概要

• 論文の詳細を見る

• As a starting material for the synthesis of mouse epidermal growth factor, a half of the molecule, the protected tetracosapeptide ester (positions 30-53), was synthesized by successive condensations of eight peptide fragments : (positions 51-53), (49-50), (46-48), (42-45), (39-41), (37-38), (34-36), (30-33).

• 公益社団法人日本薬学会の論文
• 1985-01-25

著者

• 藤井 信孝

  Faculty of Pharmaceutical Sciences, Kyoto University

• 赤路 健一

  Faculty of Pharmaceutical Sciences

• 矢島 治明

  京都大学

• 矢島 治明

  京大・薬

• 藤井 信孝

  京大 薬

• 矢島 治明

  Faculty Of Pharmaceutical Sciences Kyoto University

• 赤路 健一

  Faculty Of Pharmaceutical Sciences Kyoto University

関連論文

• Solution-Phase Synthesis of an Anti-human Immunodeficiency Virus Peptide, T22 ([Tyr^, Lys^7]-Polyphemusin II), and the Modification of Trp by the p-Methoxybenzyl Group of Cys during Trimethylsilyl Trifluoromethanesulfonate Deprotection
• Synthesis of Amaryllidaceae Alkaloids, (±)-Cherylline and (±)-Latifine
• Synthesis of Protegrin-Related Peptides and Their Antibacterial and Anti-human Immunodeficiency Virus Activity
• Studies on Peptides. CXXXVI. : Solution-Phase Synthesis of a 37-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Human Calcitonin Gene-Related Peptide (hCGRP)
• Studies on Peptides. LXXVI. Synthesis of Kassinin, a New Frog Skin Peptide
• Studies on Peptides. LXXIII. Examination of the Methanesulphonic Acid Procedure for the Synthesis of Peptides containing Methionine
• Studies on Peptides. LXIX. Selective Removal of Acid Labile α-Amino Protecting Groups with Dilute Sulfonic Acids
• Studies on Peptides. XLVIII. Application of the Trifluoromethanesulphonic Acid Procedure to the Synthesis of Tuftsin
• Studies on Peptides. CXLI. : Synthesis of a 42-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Porcine GIP (Glucose-Dependent Insulinotropic Polypeptide)
• Studies on Peptides. CXXXIX. : Solution Synthesis of a 42-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Human Glucose-Dependent Insulinotropic Polypeptide (GIP)
• Studies on Peptides. CXXXIII. : Synthesis and Biological Activity of Galanin, a Novel Porcine Intestinal Polypeptide
• Studies on Peptides. CXXXI. Synthesis of Adrenorphin and Enkephalin Analogs
• SYNTHESIS OF A 42 RESIDUE PEPTIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN GIP
• Studies on Peptides. CL. Syntheses of [D-His^2]-Analogs of Enkephalin and Adrenorphin and Several [D-Arg^2]enkephalin Analogs(Organic,Chemical)
• Studies on Peptides. CXXXIV. : Evaluation of S-1-Adamantylcysteine for Peptide Synthesis
• Enzyme Immunoassay of Somatostatin (SS)-like Immunoreactive Substance in Bovine Milk
• Studies on Peptides. CLVI. Synthesis of Second Human Calcitonin Gene-Related Peptide (β-hCGRP) by Application of a New Disulfide-Bonding Reaction with Thallium(III) Trifluoroacetate(Organic,Chemical)
• Studies on Peptides. CXLII. : Synthesis of Des-1-Ala-des-α-amino-Human Calcitonin Gene-Related Peptide
• Synthesis of Optically Pure 2-Aziridinemethanols : Versatile Synthetic Building Blocks
• Studies on Peptides. CXLVI. : Synthesis of Gln^-Motilin and Examination of Its Immunological Properites
• Studies on Peptides. CXLV. : Synthesis of a 27-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Canine Gastrin-Releasing Polypeptide (cGRP)
• Studies on Peptides. CXL. : Synthesis of Human Gastrin-Releasing Polypeptide (hGRP)
• Studies on Peptides. CXXX. Convenient Procedure for the Reduction of Methionine Sulfoxide
• SYNTHESIS OF A 27-RESIDUE PEPTIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN GASTRIN-RELEASING PEPTIDE (hGRP)
• Studies on Peptides. CV. Synthesis of Chicken Neurotensin
• Studies on Peptides. CLI. Syntheses of Cystine-Peptides by Oxidation of S-Protected Cysteine-Peptides with Thallium(III) Trifluoroacetate(Organic,Chemical)
• Studies on Peptides. CXLIII. : Evaluation of β-Methylaspartate for Peptide Synthesis
• 薬学会賞受賞冨士薫氏の業績
• Studies on Peptides. CI. Synthesis of a Wasp Venom, Mastoparan M
• Studies on Peptides. CX. Solution Synthesis of the Tetratriacontapeptide Amide corresponding to Positions 1 to 34 of Human Parathyroid Hormone
• Studies on Peptides. CIX. Synthesis of the Octatriacontapeptide Corresponding to Positions 1 to 38 of Human Parathyroid Hormone
• Synthesis of a Heptacosapeptide Amide corresponding to the Entire Amino Acid Sequence of Chicken Gastrin Releasing Peptide (GRP)
• Synthesis of a Heptacosapeptide Amide corresponding to the Entire Amino Acid Sequence of Gastric Gastrin Releasing Peptide
• 尾部下垂体ホルモンのウロテンシンIIと飲水について(内分泌学)
• 新学術会議会員に聞く
• Selective Transport of the Salts of Amino Acid Esters through an Organic Liquid Membrane with Antamanide as a Carrier
• Studies on Peptides. CXLVIII. : Application of a New Deprotecting Procedure with Trimethylsilyl Trifluoromethanesulfonate for the Syntheses of Two Porcine Spinal Cord Peptides, Neuromedin U-8 and Neuromedin U-25(Amaryllidaceae)(Organic,Chemical)
• Studies on Peptides. CLXVI. : Solid-Phase Syntheses and Immunological Properties of Fragment Peptides Related to Human Hepatitis B Virus Surface Antigen (HBsAg) and Its Pre-S2 Gene
• Studies on Peptides. CLVII. : Synthesis of a Frog-Skin Peptide, Sauvagine
• Studies on Peptides. CXXXII. : Evaluation of Two β-Carboxyl Protecting Groups of Aspartic Acid, Cycloheptyl and Cyclooctyl, for Peptide Synthesis
• Studies on Peptides. CXXXV. : Preparation of Seven Peptide Fragments for the Synthesis of Human Calcitonin Gene-Related Peptide (hCGRP)
• Studies on Peptides. CXXIV. Solution Synthesis of the Hentetracontapeptide Amide Corresponding to the Entire Amino Acid Sequence of Human Corticotropin Releasing Factor (hCRF)
• Studies on Peptides. CXXIII. Preparations of Nine Peptide Fragments for the Synthesis of Human Corticotropin Releasing Factor (hCRF)
• SYNTHESIS OF A HENTETRACONTAPEPTIDE AMIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN CORTICOTROPIN RELEASING FACTOR (hCRF)
• Studies on Peptides. CXVII. Solution Synthesis of the Tetratetracontapeptide Amide Corresponding to the Entire Amino Acid Sequence of Growth Hormone Releasing Factor, Somatocrinin
• SOLUTION SYNTHESIS OF A TETRATETRACONTAPEPTIDE AMIDE WITH GROWTH HORMONE RELEASING ACTIVITY
• Studies on Peptides. CXXXVIII. : Conventional Solution Synthesis of Bovine Hypothalamic Growth Hormone Releasing Factor (bGRF)
• Studies on Peptides. CXXXVII. : Conventional Solution Synthesis of Porcine Hypothalamic Growth Hormone Releasing Factor (pGRF)
• Further Synthesis of Enkephalinol Analogs containing the Dipeptide Unit Tyr-Arg (Kyotorphin)
• Convenient Procedure for the Preparation of α-Amino Alcohols
• Synthesis of the Pentadecapeptide corresponding to the Entire Amino Acid Sequence of Salmon α-Melanotropin II (α-MSH II)
• Solution Synthesis of a Heptacosapeptide known as Bovine γ_3-Melanotropin (γ_3-MSH)
• Studies on Peptides. CLXIV. : Solution-Phase Synthesis of a 36-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Chicken Antral Peptide
• Studies on Peptides. CLX. : Synthesis of a 33-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Human Cholecystokinin (hCCK-33)
• Antimicrobial Activity and Conformation of Tachyplesin I and Its Analogs
• Acceleration of the N^α-Deprotection Rate by the Addition of m-Cresol to Diluted Methanesulfonic Acid and Its Application to the Z(OMe)-Based Solid-Phase Syntheses of Human Pancreastatin-29 and Magainin 1
• Enzyme Immunoassay of a Substance P-like Immunoreactive Substance in Human Plasma and Saliva
• Micro-Enzyme Immunoassay of Vasoactive Untestinal Polypeptide (VIP)-like Immunoreactive Substance in Bovine Milk
• Studies on Peptides. CLXVIII. : Syntheses of Three Peptides Isolated from Horseshoe Crab Hemocytes, Tachyplesin I, Tachyplesin II, and Polyphemusin I
• Studies on Peptides. CLXVII. / Solid-Phase Syntheses and Immunological Properties of Fragment Peptides Related to Human Malaria Circumsporozoite Protein
• Immuno-affinity Purification of Specific Antibodies against Vasoactive Intestinal Polypeptide (VIP) on VIP (1-10)-Linked Polydimethylacrylamide Resin
• S-BENZYLOXYMETHYLCYSTEINE, ITS PROPERTIES AND APPLICATION IN THE SYNTHESIS OF PORCINE BRAIN NATRIURETIC PEPTIDE (pBNP)
• Studies on Peptides. CLXV. : Combination of a New Amide-Precursor Reagent and Trimethylsilyl Bromide Deprotection for the 9-Fluorenylmenthyloxycarbonyl-Based Solid-Phase Synthesis of chicken Antral Peptide
• Studies on Peptides. CLXIII. : Synthesis of Guinea Pig Vasoactive Intestinal Polypeptide(gVIP)
• Studies on Peptides. CLXII. : Synthesis of Chicken Calcitonin-Gene-Related Peptide (cCGRP) by Application of Sulfoxide-Directed Disulfide-Bond-Forming Reaction
• Studies on Peptides. CLIX. : Preparation of a Protected 33-Residue Peptide for the Synthesis of Human Cholecystokinin (hCCK-33)
• Partical Structural Revision of Porcine Pancreatic Colipase
• Synthesis of the Nonatriacontapeptide corresponding to the Entire Amino Acid Sequence of Ostrich Adrenocorticotropic Hormone
• Studies on Peptides. CVI. Synthesis of a Physalaemin-like Peptide, [Lys^5,Thr^6]-Physalaemin, isolated from the Skin of a Frog, Uperoleia rugosa
• Enzyme Immunoassay of Thyrotropin Releasing Hormone (TRH)
• Apparent Autolysis of the N-Terminal Tetrapeptide of Vasoactive Intesinal polypeptide (VIP)
• Syntheses and Biological Activities of Selenium Analogs of α-Rat Atrial Natriuretic Peptide
• Investigation of the Dimethylsulfoxide-Trifluoroacetic Acid Oxidation System for the Synthesis of Cystine-Containing Peptides
• Synthetic Study on Selenocystine-Contaning Peptides
• Studies on Peptides. CXXIX. Application of N^-Mesitylenesulfonyl-tryptophan for the Syntheses of Neuromedin B and Neuromedin C
• Studies on Peptides. CXXVII. Synthesis of a Tripentacontapeptide with Epidermal Growth Factor Activity
• Studies on Peptides. CXII. Alternative Synthesis of Heptacosapeptide, a New Gastrointestinal Polypeptide
• Studies on Peptides. LXXIV. Convenient Procedure for the Preparation of Methionine Sulphoxide Derivatives
• Studies on Peptides. LXXII. Examination of the N^ε-Alkylation of Lysine in the Methanesulphonic Acid Procedure for Peptide Synthesis
• Studies on Peptides. CXX. Synthesis of Growth Hormone Releasing Factor (GRF-37-NH_2) and N^α-Biotinyl-GRF-44-NH_2
• Studies on Peptides. CXIX. Synthesis of Growth Hormone Releasing Factor (hpGRF-40-OH)
• Studies on Peptides. CXLVII. Synthesis of Valosin, a Novel 25-Residue Peptide from Porcine Intestine(Organic,Chemical)
• Studies on Peptides CXLIV. : Synthesis and Immunological Properties of Formylmethionyl Human Adrenocorticotropin
• Studies on Peptides. CXV. Synthesis of Hylambatin, a New Frog Skin Peptide of the Kassinin Family
• Alternative Synthesis of Porcine Secretin and Apparent Autolysis of the Product
• Studies on Peptides. CXVI. Synthesis of the Protected Docosapeptide Corresponding to the C-Terminal Portion of Human Growth Hormone Releasing Factor (GRF, Somatocrinin)
• Studies on Peptides. XCVI. Behavior of S-Acetamidomethylcysteine Sulfoxide under Deprotecting Conditions in Peptide Synthesis
• Studies on Peptides. LXXXIII. Behavior of S-Substituted Cysteine Sulfoxides under Deprotecting Conditions in Peptide Synthesis
• Behaviour of S-Substituted Cysteine Sulfoxide under Acidolytical Deprotecting Conditions
• Studies on Peptides. L. Acidolysis of Protecting Groups in Peptide Chemistry by Fluorosulphonic Acid and Methanesulphonic Acid
• Studies on Peptides. CXXII. N-Succinimidyl-p-(2-nitrovinyl)-benzoate and Its m-Isomer, as Heterobifunctional Conjugating Reagents for Immunoassay
• Studies on Peptides. CXXI. N^-Mesitylenesulfonyl-tryptophan, a New Derivative for Peptide Synthesis
• Studies on Peptides. CXLIX. : Solid-Phase Synthesis of a Rabbit Stomach Peptide by Application of a New Polymer Support and a New Deprotecting Procedure(Organic,Chemical)
• Studies on Peptides. CXVIII. Synthesis of a Hybrid Growth Hormone Releasing Factor (GRF)-PHI Heptacosapeptide Amide
• Studies on Peptides. CVII. Synthesis of Urotensin II
• Studies on Peptides. CXXV. 3-(3-p-Methoxybenzylthiopropionyl)-thiazolidine-2-thione and Its Analogs as Reagents for the Introduction of the Mercapto Group into Peptides and Proteins
• Studies on Peptides. CXXVI. Synthesis of the Protected Tetracosapeptide Corresponding to Positions 30-53 of Mouse Epidermal Growth Factor (EGF)
• Studies on Peptides. XCIV. Thiazoline-2-thione as a Carboxyl-activating Reagent for Petide Synthesis
• Studies on Peptides. LI. Application of the Solid Phase Synthesis for the Preparation of Pro-Analogues of LH and FSH Releasing Hormone
• Studies on Peptides. CIV. Synthesis of Ribonuclease S'

もっと見る 閉じる

スポンサーリンク