Macrophage Stimulation Activity of the Polysaccharide Fraction from a Marine Alga (Porphyra yezoensis):Structure-Function Relationships and Improved Solubility
スポンサーリンク
概要
- 論文の詳細を見る
The polysaccharide fraction from Porphyra yezoensis (PASF) has already been shown to stimulate murine phagocytic functions in vivo and in vitro [Y. Yoshizawa et al, Biosci. Biotech. Biochem. , 57, 1862-1866 (1993)]. In this study, various treatments were applied to PASF to assess its structure-function relationships. Desulfation of PASF decreased in vitro macrophage-stimulation activity, while further sulfation of PASF did not change the activity. Among 7 fractions obtained by anion-exchange chromatography of PASF, stronger activity was found in the fractions having a lower or higher sulfate content than in those having a medium sulfate content. Digests of PASF with β-agarase showed higher activity and solubility, and lower viscosity, than undigested PASF. These results indicate that the sulfate groups in PASF, probably porphyran, contributed to the macrophage stimulating activity, although a larger number of sulfate groups did not always cause stronger activity.
- 社団法人日本農芸化学会の論文
- 1995-10-23
著者
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KAMINOGAWA Shuichi
Department of Food Science and Technology, College of Bioresource Sciences, Nihon University
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FUKUI Fumio
Research and Development Center, Showa Sangyo Co., Ltd.
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Fukui F
Showa Sangyo Co. Ltd. Ibaraki Jpn
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Fukui Fumio
Research And Development Center Showa Sangyo Co. Ltd.
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Fukui Fumio
Fermentation Research Laboratories Sankyo Co. Ltd.
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Kaminogawa Shuichi
Department Of Applied Biological Chemistry Division Of Agriculture And Agricultural Life Sciences Th
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YOSHIZAWA Yasuko
Research and Development Center, Showa Sangyo Co., Ltd.
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AMETANI Akio
Applied Biological Chemistry, University of Tokyo
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AMETANI Akio
Department of Applied Biological Chemistry, The University of Tokyo
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Kametani Y
Applied Biological Chemistry University Of Tokyo
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Ametani Akio
Department Of Applied Biological Chemistry The University Of Tokyo:(present Address)torrey Pines Ins
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Yoshizawa Y
Research And Development Center Showa Sangyo Co. Ltd.
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Itoh M
T. Hasegawa Co. Ltd. Kawasaki Jpn
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Nomura K
Shin Nihon Chemical Co. Ltd.
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TSUNEHIRO Jun
Research and Development Center, Showa Sangyo Co., Ltd.,
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NOMURA Kazuyo
R&D Department, Shin Nihon Chemical Co., Ltd.
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ITOH Masao
R&D Department, Shin Nihon Chemical Co., Ltd.
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Tsunehiro J
Showa Sangyo Co. Ltd. Ibaraki Jpn
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Tsunehiro Jun
Research And Development Center Kashima Laboratory Showa Sangyo Co. Ltd.
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Kaminogawa S
Dep. Of Food Sci. And Technol. Nihon Univ.
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Kaminogawa Shuichi
Department Of Agricultural Chemistry Faculty Of Engineering The University Of Tokyo
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Yoshizawa Yasuko
Research & Development Center Showa Sangyo Co. Ltd
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