Enhancing Effect of Interleukin-4 on the Secretion of Interferon-γ by α_<s1>-Casein-specific CD8^+ T Cells
スポンサーリンク
概要
- 論文の詳細を見る
α_<s1>-Casein-specific CD8^+ T cell clones expressed the interleukin (IL)-4 receptor, although they did not secrete detectable IL-4. We found that IL-4 significantly enhanced the secretion of interferon (IFN)-γ by these CD8^+ T cell clones. IL-4 also enhanced the secretion of IFN-γ induced by stimulating the immobilized anti-CD3 antibodies of polyclonal CD8^+ T cells which had been isolated from lymph nodes and were stimulated in vitro with the immobilized anti-CD3 antibody and IL-2. In addition, IL-4 added at the time of this first in vitro stimulation induced strong IFN-γ productivity, as well as IL-4 and IL-10 productivity, which were detectable upon restimulation of these cells. Results are discussed in relation to the inhibitory effects of IFN-γ production on IL-4-producing cells.
- 社団法人日本農芸化学会の論文
- 1997-07-23
著者
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HISATSUNE Tatsuhiro
Department of Integrated Biosciences, The University of Tokyo
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Hisatsune Tatsuhiro
Department Of Applied Biological Chemistry The University Of Tokyo
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Hisatsune T
Univ. Tokyo Tokyo Jpn
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Kato H
Department Of Agricultural Chemistry The University Of Tokyo
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Kato H
Department Of Food Science Otsuma Women's University
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Kato Hiromichi
Department Of Food Science Ohtsuma University
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KAMINOGAWA Shuichi
Department of Food Science and Technology, College of Bioresource Sciences, Nihon University
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Kato H
Otsuma Women's Univ. Tokyo Jpn
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Nishijima Ken-ichi
Department of Biotechnology, Graduate School of Engineering, Nagoya University
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Nishijima Ken-ichi
Nagoya University
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Kaminogawa Shuichi
Department Of Applied Biological Chemistry Division Of Agriculture And Agricultural Life Sciences Th
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Kato H
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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KOHYAMA Masako
Department of Applied Biological Chemistry, The University of Tokyo
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KATO Hiroko
Department of Applied Biological Chemistry, The University of Tokyo
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KAKEHI Masahiro
Department of Applied Biological Chemistry, The University of Tokyo
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Kato Hiroko
Department Of Anesthesia Kobe City General Hospital
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Kohyama Masako
Department Of Applied Biological Chemistry The University Of Tokyo
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Kakehi Masahiro
Department Of Applied Biological Chemistry The University Of Tokyo
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Kaminogawa S
Dep. Of Food Sci. And Technol. Nihon Univ.
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Kato Hiroshi
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Kaminogawa Shuichi
Department Of Agricultural Chemistry Faculty Of Engineering The University Of Tokyo
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Nishijima Ken-ichi
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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Nishijima Ken-ichi
Department Of Applied Biological Chemistry The University Of Tokyo:(present Address)department Of Bl
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Kawata Hiroaki
From The Department Of Surgery Course Of Interventional Medicine (el) Osaka University Graduate Scho
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