The Tyrosine Kinase Activity of the Chicken Insulin Receptor Is Similar to That of the Human Insulin Receptor

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概要

• 論文の詳細を見る

• The tyrosine kinase activity of a chimeric insulin receptor composed of the extracellular domain of the human insulin receptor (IR) and the intracellular domain of the chicken IR was compared with wild-type human IR. The degrees of autophosphorylation, phosphorylation of IRS-1,and in vitro phosphorylation of an exogenous substrate after stimulation by human insulin were similar to that seen with the human IR. We conclude that the insulin resistance of chickens is not attributable to a lower level of intrinsic tyrosine kinase activity of IR.

• 社団法人日本農芸化学会の論文
• 2000-04-23

著者

• SUGAHARA Kunio

  Department of Animal Science, Faculty of Agriculture, Utsunomiya University

• Sugahara K

  Department Of Animal Science Utsunomiya University

• Roberts C

  Oregon Health And Sci. Univ. Oregon

• Sugahara Kunio

  Department Of Animal Science Division Of Bio-productive Science Faculty Of Agriculture Utsunomiya Un

• Kato H

  Department Of Agricultural Chemistry The University Of Tokyo

• Kato H

  Department Of Food Science Otsuma Women's University

• Kato Hiromichi

  Department Of Food Science Ohtsuma University

• Sugahara Kunio

  宇都宮大学 農学部

• KATO Hisanori

  Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo

• OKUBO Yumiko

  Clinical Endocrine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Nationa

• MATSUMURA Yuki

  Department of Animal Science, Faculty of Agriculture, Utsunomiya University

• ROBERTS Charles

  Department of Pediatrics, Oregon Health Sciences University

• LEROITH Derek

  Clinical Endocrine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Nationa

• Kato H

  Otsuma Women's Univ. Tokyo Jpn

• Matsumura Yasuki

  Division Of Food Science And Biotechnology Graduate School Of Agriculture Kyoto University

• Roberts Charles

  Department Of Pediatrics Oregon Health Sciences University

• Kato H

  Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni

• Okubo Yumiko

  Clinical Endocrine Branch National Institute Of Diabetes And Digestive And Kidney Diseases National

• Leroith Derek

  Clinical Endocrine Branch National Institute Of Diabetes And Digestive And Kidney Diseases National

• Kato Hiroshi

  Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni

• Matsumura Y

  Graduate School Of Agriculture Kyoto University

• Kawata Hiroaki

  From The Department Of Surgery Course Of Interventional Medicine (el) Osaka University Graduate Scho

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