Little or No Response to 24-hr Water-Deprivation of Fos-Like Immunoreactivity in Vasporessinergic Magnocellular Neurons in the Hypothalamus of Hereditary Microphthalmic Rats

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概要

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• In normal rats, 24-hr water-deprivation was found to cause a significant increase in the plasma concentration of arginine vasopressin (AVP), and marked induction of Fos in the AVP-positive magnocellular neurons in the paraventricular nucleus (PVN) and the supraoptic nucleus (SON) of the hypothalamus. On the other hand, 24-hr water-deprivation also caused a significant increase in the plasma AVP concentration in hereditary microphthalmic rats, but much less than in normal rats. Consistent with this, the extent of induction of Fos in the nuclei of the PVN and SON of these rats was lesser than in normal rats. These results suggest that hereditary microphthalmic rats have a defect or decrease in the response to water-deprivation of vasopressinergic magnocellular neurons in the PVN and SON.

• 社団法人　日本実験動物学会の論文

著者

• Sugita Shoei

  Department of Animal Science, Faculty of Agriculture, Utsunomiya University

• Sugita Shoei

  Department Of Animal Science Faculty Of Agriculture Utsunomiya University

• SUGAHARA Kunio

  Department of Animal Science, Faculty of Agriculture, Utsunomiya University

• Sugahara K

  Faculty Of Agriculture Utsunomiya University

• SUGITA Shoei

  Faculty of Agriculture, Utsunomiya University

• Sugahara K

  Department Of Animal Science Faculty Of Agriculture Utsunomiya University

• Sugahara Kunio

  Department Of Animal Science Division Of Bio-productive Science Faculty Of Agriculture Utsunomiya Un

• Sugahara Kunio

  Faculty Of Agriculture Utsunomiya University

• Sugita S

  Utsunomiya Univ. Tochigi

• NAGAI Katsuya

  Division of Protein Metabolism, Institute for Protein Research, Osaka University

• ISOJIMA Yasushi

  Division of Protein Metabolism, Institute for Protein Research, Osaka University

• NAGAI Nobuo

  Division of Protein Metabolism, Institute for Protein Research, Osaka University

• NAKAGAWA Hachiro

  Department of Animal Science, Faculty of Agriculture, Utsunomiya University

• Nagai Katsuya

  Division Of Protein Metabolism Institute For Protein Research Osaka University

• Nakagawa Hachiro

  Department Of Animal Science Faculty Of Agriculture Utsunomiya University

• Isojima Y

  Osaka Univ. Osaka

• Isojima Yasushi

  Division Of Protein Metabolism Institute For Protein Research Osaka University

• Nagai Nobuo

  Division Of Protein Metabolism Institute For Protein Research Osaka University

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