Diurnal Fluctuation in the Enzyme Activity and the Messenger RNA Level of Pineal Serotonin N-Acetyltransferase in Normal and Hereditary Microphthalmic Rats
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概要
- 論文の詳細を見る
The enzyme activity and the messenger RNA level of pineal serotonin N-acetyltransferase were more than 20- and 50-fold higher, respectively, in the dark period than in the light period in normal rats. In hereditary microphthalmic rats, however, the serotonin N-acetyltransferase activity and its mRNA level did not undergo a great diurnal change through the light and dark periods. These results indicate that the diurnal rhythms of the activity and the mRNA level of serotonin n-acetyltransferase are not detected in the pineal gland of hereditary blind rats, suggesting free-running rhythms in individual animals due to desynchronization of their circadian rhythms by a lack of their optic nerve.
- 社団法人日本農芸化学会の論文
- 1997-12-23
著者
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KATO Hisanori
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
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Fu Zhengwei
Department Of Applied Biochemistry United Graduate School Tokyo University Of Agriculture And Technl
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Kato Hisanori
Departments Of Applied Biological Chemistry And Animal Sciences Faculty Of Agriculture Utsunomiya Un
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Tanaka Hideyuki
Department Of Cardiology Nihon University Surugadai Hospital
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SHIM Suhyeun
Department of Applied Biochemistry, United Graduate School, Tokyo University of Agriculture and Tech
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Shim Suhyeun
Department Of Applied Biochemistry United Graduate School Tokyo University Of Agriculture And Technl
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Tanaka Hideyuki
Department Of Bioproductive Science Division Of Applied Biochemistry Utsunomiya University
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Tanaka Hideyuki
Department Of Agricultural Chemistry Faculty Of Agriculture Utsunomiya University
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Tanaka Hideyuki
Departments Of Applied Biological Chemistry And Animal Sciences Faculty Of Agriculture Utsunomiya Un
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