Changes of Hepatic Ornithine Decarboxylase in Rats by a Zein Diet(Food & Nutrition)
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概要
- 論文の詳細を見る
The effects of dietary protein on the ornithine decarboxylase (ODC) activity in rat liver were investigated, using whole egg protein, casein, gluten, and zein as the protein sources. In short-term feeding (fast-refed), ODC was induced in response to the nutritive value of dietary protein. In long-term feeding (2 weeks), howeyer, ODC was induced by only the zein diet. At the same time, both the ornithine carbamoyltransferase (OCT) and ornithine-oxo-acid aminotransferase (OAT) activities were markedly decreased. OCT and OAT were specifically inhibited by leucine in vitro. ODC was also induced by an amino acid mixture simulating zein (A-1). Moreover, ODC was decreased by the diet (A-2) in which leucine was reduced from A-1, and was increased by the diet in which ornithine was added to A-2. These results suggest that the induction of ODC by feeding the zein diet for 2 weeks is due to the increased concentration of ornithine, arising mainly from the inhibition of OCT and OAT by leucine, which is contained in a large quantity in zein.
- 社団法人日本農芸化学会の論文
- 1989-03-23
著者
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Tanaka Hideyuki
Department of Cardiology, Nihon University Surugadai Hospital
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KIMURA Shoji
Department of Pharmacology, Kagawa University Medical School
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Kimura S
Department Of Agricultural Chemistry Faculty Of Agriculture Utsunomiya University
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OGURA Masaji
Department of Agricultural Chemistry, Faculty of Agriculture, Utsunomiya University
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YAJIMA Haruyoshi
Department of Agricultural Chemistry, Faculty of Agriculture, Utsunomiya University
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Ogura Masaji
Department Of Agricultural Chemistry Faculty Of Agriculture Utsunomiya University
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Kimura Shoji
Department Of Agricultural Chemistry Faculty Of Agriculture Utsunomiya University
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Tanaka H
School Of Pharmaceutical Sciences Kitasato University And Research Center For Biological Function Th
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Yajima Haruyoshi
Department Of Agricultural Chemistry Faculty Of Agriculture Utsunomiya University
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Tanaka Hideyuki
Department Of Cardiology Nihon University Surugadai Hospital
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Tanaka Hideyuki
Department Of Agricultural Chemistry Faculty Of Agriculture Utsunomiya University
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