Immunohistochemical Detection of Tyrosine Hydroxylase and Concentrations of Monoamines in the Substantia Nigra and Hypothalamus of Hereditary Microphthalmic Rats
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概要
- 論文の詳細を見る
We compared tyrosine hydroxylase immunoreactivity in the substantia nigra and hypothalamus of hereditary microphthalmic rats with that of normal rats. A considerable number of neuronal cell bodies expressing tyrosine hydroxylase were present in the substantia nigra of the microphthalmic mutant as well as normal rats. Neuronal cells positive for tyrosine hydroxylase in the hypothalamus were fewer than in the substantia nigra in both rats. The concentrations of monoamines (dopamine, noradrenaline, adrenaline, and serotonin) in the substantia nigra and hypothalamus in the microphthalmic mutant were approximately the same as those of normal rats, although the diurnal fluctuation of a few monoamines was observed in normal rats. These results suggest that the metabolic aspects of catecholamine in the substantia nigra and hypothalamus of the microphthalmic mutant rat do not markedly differ from those of normal rats.
- 社団法人 日本実験動物学会の論文
- 2001-10-01
著者
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Tanaka Hideyuki
Department of Cardiology, Nihon University Surugadai Hospital
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Kim Sung
Department of Bioengineering and Technology, College of Engineering, Kangwon National University
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Kim Sung
Department Of Genetic Engineering Chosun University
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Sugita S
Utsunomiya Univ. Tochigi Jpn
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Sugita Shoei
Animal Science Faculty Of Agriculture Utsunomiya University
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Sugahara Kunio
Animal Science Faculty Of Agriculture Utsunomiya University
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Kim Sung
Department Of Anatomy
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SHIM Su
Departments of Applied Biological Chemistry
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Tanaka Hideyuki
Department Of Cardiology Nihon University Surugadai Hospital
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Shim Su
Department Of Radiation Oncology Yonsei Cancer Center
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Tanaka Hideyuki
Department Of Bioproductive Science Faculty Of Agriculture Utsunomiya University
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Tanaka Hideyuki
Department Of Bioproductive Science Division Of Applied Biochemistry Utsunomiya University
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Tanaka Hideyuki
Departments Of Applied Biological Chemistry
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Tanaka Hideyuki
Department Of Agricultural Chemistry Faculty Of Agriculture Utsunomiya University
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