Neuroprotection and Enhancement of Learning and Memory by BF-7
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概要
- 論文の詳細を見る
To investigate whether BF-7 improves the learning and memory of normal people, the Rey-Kim Memory Test was performed in a placebo group (32 persons), BF-7 200 mg group (33 persons), and BF-7 400 mg group (34 persons). BF-7 significantly enhanced learning and memory function in a dose-dependent manner. Our results show that BF-7 protects neurons from amyloid beta (Aβ) toxicity and reduces oxidative stress. We measured the levels of acetylcholine in the brain in a memory impairment animal model. Administration of BF-7 significantly increased acetylcholine levels. It is assumed that the protection of neurons and maintaining the appropriate acetylcholine levels are mechanisms by which BF-7 improves brain function. The results suggest that BF-7 is effective in improving learning and memory ability.
- 公益社団法人日本薬学会の論文
- 2005-06-01
著者
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Kim Sung
Department of Bioengineering and Technology, College of Engineering, Kangwon National University
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Lee Moo
Department Of Anatomy Chonbuk National University Medical School
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KIM Yong
Department of Metallurgy and Materials Science, Hanyang University
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KIM Dae
Department of Anatomy and Center for Advanced Medical Education by BK21 Project, Inha University Col
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Yeo Joo-hong
Applied Entomology Division Department Of Sericulture And Entomology National Institute Of Agricultu
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Yeo Joo-hong
韓国
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Lee Won
Department of Internal Medicine, institute of Medical Research, Sungkyunkwan University School of Me
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KANG Yong
Department of Dermatology, Seoul National University College of Medicine, Laboratory of Cutaneous Ag
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Kim Dae
Dep. Of Environmental And Health Chemistry Coll. Of Pharmacy Chung-ang Univ.
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Lee Kwang-gill
Applied Entomology Division Department Of Sericulture And Entomology National Institute Of Agricultu
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Kim Sung
Department Of Anatomy
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Kim Dae
Department Of Anatomy And Center For Advanced Medical Education By Bk21 Project Inha University Coll
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Lee Won
Department Of Agricultural And Biological Engineering University Of Florida
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Kim Yong
Department Of Pharmacology College Of Medicine Seoul National University
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Kang Yong
Department Of Dermatology Seoul National University College Of Medicine
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Kim Yong
Department And Research Institute Of Rehabilitation Medicine Yonsei University College Of Medicine
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Lee Moo
Department Of Physiology College Of Medicine Chung-ang University
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Kang Yong
Department Of Chemical And Biological Engineering Korea University
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Kang Yong
Department Of Anatomy
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Lee Won
Department Of Anatomy
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Kim Seok
Department Of Environmental & Health Chemistry College Of Pharmacy Chung-ang University
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Kang Vong
Department of Anatomy
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Kim Sung
Department of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Gyeonggi 440-746, Republic of Korea
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Kim Sung
Department of Advanced Materials Engineering for Information and Electronics, Kyung Hee University, Yongin, Gyeonggi 446-701, Republic of Korea
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