T Cell Response to Hen's Egg Ovomucoid(Biological Chemistry)
スポンサーリンク
概要
- 論文の詳細を見る
To analyze the T cell reactivity to ovomucoid (OM), one of the potent allergens in hen's eggs, the antigen-specific T cell proliferation assay was done. In the case of C3H/He and BALB/c mice, proliferative responses of OM-primed T cells to all domains (DI, DII, DIII) of OM were observed, but the response to DI was inferior to the other domains. The T cells from C57BL/6 responded to DIII and DII, but not at all to DI. These results suggest that each domain has common site(s) recognized by T cells, reflecting their homologies. Furthermore, the T cell reactivity to reduced carboxymethylated OM (RCM-OM), which has a conformation distinct from native OM, was examined. RCM-OM did not stimulate the T cells immunized with native OM, implying that OM-specific T cells recognize the conformational epitopes dependent on the tertiary structure of OM. This unique profile of the T cell reactivity to OM should be useful for analyzing the mechanism of the antigen processing and presentation of APC and the subsequent T cell antigen recognition.
- 社団法人日本農芸化学会の論文
- 1988-10-23
著者
-
山内 清
大阪市大 工
-
ENOMOTO Atsushi
Department of Pathology, Nagoya University Graduate School of Medicine
-
YAMAUCHI Kunio
Department of Agricultural Chemistry, The University of Tokyo
-
KURISAKI Jun-ichi
National Institute of Agrobiological Sciences
-
KAMINOGAWA Shuichi
Department of Food Science and Technology, College of Bioresource Sciences, Nihon University
-
AOKI YOSHIKAZU
Department of Earth and Planetary Sciences, Faculty of Science, Kyushu University
-
Kaminogawa Shuichi
Department Of Applied Biological Chemistry Division Of Agriculture And Agricultural Life Sciences Th
-
Aoki Yoshikazu
Department Of Agricultural Chemistry The University Of Tokyo
-
Yamauchi K
Univ. Tokyo Tokyo Jpn
-
Yamauchi Kunio
Department Of Agricultural Chemistry The University Of Tokyo
-
Kaminogawa S
Dep. Of Food Sci. And Technol. Nihon Univ.
-
Enomoto Atsushi
Department Of Biological And Chemical Engineering Faculty Of Engineering Gunma University
-
KURISAKI Jun-ichi
Department of Agricultural Chemistry, The University of Tokyo
-
Kaminogawa Shuichi
Department Of Agricultural Chemistry Faculty Of Engineering The University Of Tokyo
-
Kurisaki J
National Institute Of Agrobiological Sciences
-
KURISAKI Jun-ichi
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
関連論文
- Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells
- Milk Fat Globule Membrane Proteins in Aseptically Packed Ultra-heat-treated Milk: Changes during Storage
- Bacteroides Induce Higher IgA Production Than Lactobacillus by Increasing Activation-Induced Cytidine Deaminase Expression in B Cells in Murine Peyer’s Patches
- Stimulation of the Secretion of Pro-Inflammatory Cytokines by Bifidobacterium Strains
- Dietary Melibiose Regulates Th Cell Response and Enhances the Induction of Oral Tolerance
- Characteristic Intestinal Microflora of Specific Pathogen-Free Mice Bred in Two Different Colonies and their Influence on Postnatal Murine Immunocyte Profiles
- Role of Organic Anion Transporters in the Tubular Transport of Indoxyl Sulfate and the Induction of its Nephrotoxicity.(GENERAL SESSION BY POSTER PRESENTATION)(KIDNEYS AND URINARY EXCRETION SYSTEM)
- RET receptor signaling : Dysfunction in thyroid cancer and Hirschsprung's disease
- Disruption of Microbial Cells by the Flash Discharge of High-pressure Carbon Dioxide
- Synthesis of Fluorescent Peptides and Application for β-Structural Peptide
- Amphiphilic Peptides from pH-Dependent β-Structure in Phospholipid Membrane
- DNA-Synthesis Stimulating Peptide from Bovine β-Casein(Biological Chemistry)
- DNA-Synthesis Stimulating Peptides from Human β-Casein(Biological Chemistry)
- Presence of Cell Growth Promoting Peptides in Chicken Egg White Extract(Food & Nutrition)
- Stimulatory Effect of Human Lactoferrin on DNA Synthesis in BALB/c 3T3 Cells
- サトウキビ抽出液のブタ免疫応答調節能(免疫学)
- OJ-181 A Novel Akt Substrate Girdin is an Essential Regulator of Cytoskeleton and Cell Motility in Endothelial Cells(Regeneration (angiogenesis / myocardial regeneration)-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-097 The Novel Akt Substrate, Girdin, Plays Essential Roles in Signaling Pathways after VEGF-A Stimulation(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Societ
- Increased Expression after X-Irradiation of MUC1 in Cultured Human Colon Carcinoma HT-29 Cells
- Effects of α-Tocopherol Levels in Extrusion Pellets on In vivo Lipid Peroxidation Levels and Antioxidant Activities in Cultured Yellowtail Seriola quinqueradiata Injected with the Causative Bacteria of Fish Jaundice
- 古細菌脂質膜モデルと機能
- 人工細胞膜を工夫する(話題を探る)
- C-Pペプチド (C-P化合物の代謝と機能)
- In vivo Lipid Peroxidation Levels and Antioxidant Activities of Cultured and Wild Yellowtail
- Simultaneous determination of ascorbic acid and dehydroascorbic acid in fish tissues by high-performance liquid chromatography
- Occurrence of Hyperbilirubinemia in Cultured Red Sea Bream
- Role of Olfaction in Food Preference as Evaluated in an Animal Model
- Apoptosis of Antigen-specific T Cells Induced by Oral Administration of Antigen : Comparison of Intestinal and Non-intestinal Immune Organs
- Isolation and Characterization of a β-Primeverosidase Concerned with Alcoholic Aroma Formation in Tea Leaves
- A Primeverosidase as a Main Glycosidase Concerned with the Alcoholic Aroma Formation in Tea Leaves
- Carboxypeptidase Taq, a Thermostable Zinc Enzyme, from Thermus aquaticus YT-1 : Molecular Cloning, Sequencing, and Expression of the Encoding Gene in Escherichia coli
- Purification and Characterization of a Thermostable Carboxypeptidase (Carboxypeptidase Taq) from Thermus aquaticus YT-1
- Relationships between 4-Hydroxy-2-nonenal, 2-Thiobarbituric Acid Reactive Substances and n-6 Polyunsaturated Fatty Acids in Refrigerated and Frozen Pork
- A Lipid Peroxidation-derived Aldehyde, 4-Hydroxy-2-nonenal and ω6 Fatty Acids Contents in Meats
- Suppression of Collagen-Induced Arthritis in DBA/1J Mice by Preimmunization with House Dust Mite Extract
- IgE-antibody Specificities of the Patients Allergic to Meat Products
- Enhancing Effect of Interleukin-4 on the Secretion of Interferon-γ by α_-Casein-specific CD8^+ T Cells
- α_-Casein-specific CD8^+ T Cell Clone That Inhibits Its Own Interferon-γ Production by Producing Interleukin-10
- Synthesis and Structural Analysis of The Ligand Binding Site of Macrophage Scavenger Receptor
- Synthesis and Adhesion Activity of a Heterotrimeric Peptide Containing the Cell Adhesion Site of Type I Collagen
- Amino Acid Residue Substitution at T-Cell Determinant-flanking Sites in β-Lactoglobulin Modulates Antigen Presentation to T Cells through Subtle Conformational Change(Food & Nutrition Science)
- In Vivo Macrophage-stimulation Activity of the Enzyme-degraded Water-soluble Polysaccharide Fraction from a Marine Alga (Gracilaria verrucosa)
- Macrophage Stimulation Activity of the Polysaccharide Fraction from a Marine Alga (Porphyra yezoensis):Structure-Function Relationships and Improved Solubility
- Activation of Murine Macrophages by Polysaccharide Fractions from Marine Algae (Porphyra yezoensis)
- Antigen Feeding Increases Frequency and Antigen-specific Proliferation Ability of Intraepithelial CD4^+ T Cells in αβ T Cell Receptor Transgenic Mice(Food & Nutrition Science)
- Antigen Presentation by Peyer's Patch Cells Can Induce both Th1- and Th2-type Responses Depending on Antigen Dosage, but a Different Cytokine Response Pattern from That of Spleen Cells(Food & Nutrition Science)
- Characterization of a Water-soluble Polysaccharide Fraction with Immunopotentiating Activity from Bifidobacterium adolescentis M101-4
- Screening for the Immunopotentiating Activity of Food Microorganisms and Enhancement of the Immune Response by Bifidobacterium adolescentis M101-4
- Strong Influence of the Processing of the Antigen on Negative Effects on T Cell Activation by Regions Outside the Determinant Area of Bovine α_-Casein
- Production and Characterization of Anti-human Insulin Antibodies in the Hen's Egg(Biological Chemistry)
- Structure of α_-Casein at an Oil/Water Interface: An Analytical Approach Using Immunochemical Methods(Biological Chemistry)
- Methionine Oxidation and Proline cis-trans Isomerization in α_-Casein on Emulsification with Oxidized Lipid(Biological Chemistry)
- Effect of Orally Administered Non-Viable Lactobacillus Cells on Murine Humoral Immune Responses
- Cytokine Production by the Murine Macrophage Cell Line J774.1 after Exposure to Lactobacilli(Microbiology & Fermentation Technology)
- Adhesion of Lactic Acid Bacteria to Caco-2 Cells and Their Effect on Cytokine Secretion
- In situ demonstration of intraepithelial lymphocyte adhesion to villus microvessels of the small intestine
- Analysis of Cytokine Producing Activity of Intestinal Intraepithelial T Cells from TCR β-Chain and δ-Chain Mutant Mice
- Dietary Nucleotides Increase the Proportion of a TCRγδ^+ Subset of Intraepithelial Lymphocytes (IEL) AND IL-7 Production by Intestinal Epithelial Cells (IEC) : Implications for Modification of Cellular and Molecular Cross-talk between IEL and IEC by Dieta
- T Cell Recognition of β-Lactoglobulin(Biological Chemistry)
- Expression and Secretion of Bovine β-Lactoglobulin in Saccharomyces cerevisiae(Food & Nutrition)
- Interactions of Human-and Rat-Organic Anion Transporters With Pravastatin and Cimetidine
- Expression of Ret finger protein correlates with outcomes in endometrial cancer
- Girding for migratory cues : roles of the Akt substrate Girdin in cancer progression and angiogenesis
- Purification, Characterization, and Gene Cloning of Lysyl Aminoeptidase from Streptococcus thermophilus YRC001(Biochemistry & Molecular Biology)
- Food allergens and mucosal immune systems with special reference to recognition of food allergens by gut-associated lymphoid tissue
- Cloning and Nucleotide Sequencing of Genes Encoding Mn-Superoxide Dismutase and Class II Fumarase from Thermus aquaticus YT-1
- Cloning of Genes of the Aminopeptidase T Family from Thermus thermophilus HB8 and Bacillus stearothermophilus NCIB8924 : Apparent Similarity to the Leucyl Aminopeptidase Family
- Comparison of pH and Ionic Strength Dependence of Interactions between Monoclonal Antibodies and Bovineβ-Lactoglobulin
- Preliminary Human Study for Possible Alteration of Serum Immunoglobulin E Production in Perennial Allergic Rhinitis with Fermented Milk Prepared with Lactobacillus gasseri TMC0356
- Bifidobacterium suppresses IgE-mediated degranulation of rat basophilic leukemia (RBL-2H3) cells
- Modified Keratin Sponge : Binding of Bone Morphogenetic Protein-2 and Osteoblast Differentiation(MEDICAL BIOTECHNOLOGY)
- A film of collagen/calcium phosphate composite prepared by enzymatic mineralization in an aqueous phase( Ceramics for Biomedical Applications in Asian Countries)
- Drug Release from Hydrogel Containing Albumin as Crosslinker(MEDICAL BIOTECHNOLOGY)
- Keratin Sponge: Immobilization of Lysozyme(MEDICAL BIOTECHNOLOGY)
- CD109 expression in basal-like breast carcinoma
- Establishment of a Primary Culture Method for Mouse Intestinal Epithelial Cells by Organ Culture of Fetal Small Intestine
- T Cell Response to Hen's Egg Ovomucoid(Biological Chemistry)
- Comparison of Four Distinct Idiotypes of Monoclonal Antibodies against Hen's Egg Ovomucoid(Biological Chemistry)
- Suppression of the Systemic Immune Response to Casein by Oral Administration of a Tryptic Digest of Casein
- High-performance liquid chromatographic determination of lipoamidase (lipoyl-X hydrolase) activity with a novel substrate, lipoyl-6-aminoquinoline
- New Lactococcus Strain with Immunomodulatory Activity : Enhancement of Th1-Type Immune Response
- High-pressure Proteolytic Digestion of Food Proteins : Selective Elimination of β-Lactoglobulin in Bovine Milk Whey Concentrate(Food & Nutrition)
- Molecular Cloning and Nucleotide Sequence of the Aminopeptidase T Gene of Thermus aquaticus YT-1 and Its High-level Expression in Escherichia coli(Microbiology & Fermentation Industry)
- Occurrence of High Molecular Weight EGF Complexes in Human Milk(Food & Nutrition)
- Lipid Composition of Plasma Membranes Isolated from Lactating Bovine Mammary Gland(Biological Chemistry)
- Preparation of Monoclonal Antibody against Bovine β-Lactoglobulin and Its Unique Binding Affinity(Biological Chemistry)
- Emulsifying Properties of Peptides Obtained from the Hydrolyzates of β-Casein(Food & Nutrition)
- Dietary Melibiose Regulates Th Cell Response and Enhances the Induction of Oral Tolerance
- Comparison between the Antigenicity of Native and Unfolded β-Lactoglobulin(Biological Chemistry)
- Effect of Bound Phosphate on the Calcium-binding Ability and Calcium-dependent Precipitability of Human β-Casein(Food & Nutrition)
- Bacteroides Induce Higher IgA Production Than Lactobacillus by Increasing Activation-Induced Cytidine Deaminase Expression in B Cells in Murine Peyer's Patches
- Synthesis and Liposome-Formation of a Lipid Bearing Cell-Adhesion Peptide Sequence
- Inactivation of Food Microorganisms by High-pressure Carbon Dioxide Treatment with or without Explosive Decompression
- Lethal Effect of High-Pressure Carbon Dioxide on a Bacterial Spore
- Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease
- Isolation and Characterization of a Thermostable Aminopeptidase (Aminopeptidase T) from Thermus aquaticus YT-1, an Extremely Thermophilic Bacterium(Biological Chemistry)
- Preparation of Anti-bovine β-Casein Monoclonal Antibody and Analysis of the Interaction between the Antibody and β-Casein Fragment(Biological Chemistry)
- Synthesis and Properties of Dimeric Glycerophospholipid: 2,2'-Dotriacontanedioylbis(1-Palmitoyl-sn-Glycero-3-Phosphocholine)^1
- 1,2-Dotriacontanedioyl-sn-Glycero-3-Phosphocholine : A Cyclic Lipid Used for Phospholipase A_2-Catalvzed Modulation of the Liposome Surface Charge
- Effect of Whey Hydrolysate Formula on the Transfer of β-Lactoglobulin into Serum and Milk in Mice