Effects of a Hydrogenated Isomaltooligosaccharide Mixture on Glucan Synthesis and on Caries Development in Rats
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概要
- 論文の詳細を見る
The caries inhibitory effect of the hydrogenated derivative of an isomaltooligosaccharides mixture (IMO-H) was examined in vitro and in vivo experiments. IMO-H could not be used as a substrate for the crude glucosyltransferases (GTases) of Streptococcus sobrinus 6715 to synthesize water-insoluble glucan. Moreover, it not only significantly inhibited the synthesis of water-insoluble glucan from sucrose, but also the sucrose-dependent adherence of these growing cells the glass surfaces. In the in vivo experiment, the addition of IMO-H to a sucrose-containing diet resulted in significant reduction of caries development in specific-pathogen-free (SPF) rats infected with S. sobrinus 6715.
- 社団法人日本農芸化学会の論文
- 1997-12-23
著者
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SHIOTA Masao
Technical Division, Showa Sangyo Co., Ltd.
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Shiota M
Showa Sangyo Co. Ltd. Ibaraki Jpn
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Shiota Masao
Technical Division Showd Sangyo Co. Ltd.
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MATSUKUBO TAKASHI
Department of Epidemiology and Public Health, Tokyo Dental College
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TAKAESU YOSHINORI
Department of Epidemiology and Public Health, Tokyo Dental College
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TSUNEHIRO Jun
Research and Development Center, Showa Sangyo Co., Ltd.,
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Tsunehiro J
Showa Sangyo Co. Ltd. Ibaraki Jpn
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Tsunehiro Jun
Research And Development Center Kashima Laboratory Showa Sangyo Co. Ltd.
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Matsukubo Takashi
Dept. Of Epidemiology And Public Health Tokyo Dental College
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Matsukubo T
Department Of Epidemiology And Public Health Tokyo Dental College
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Matsukubo Takashi
Department Of Epidemiology And Public Health Tokyo Dental College
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Takaesu Y
Tokyo Dental Coll. Chiba Jpn
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Takaesu Yoshinori
Department Of Epidemiology And Public Health Tokyo Dental College
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