Studies on Pyrimidine Derivatives. XXIII. Synthesis of Acylmethylpyrimidines and Related Compounds via Imidoyl-substituted Oxosulfonium Ylides

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概要

• 論文の詳細を見る

• The reaction of 2- and 4-chloropyrimidines with dimethyloxosulfonium methylide afforded the corresponding pyrimidinylmethylides. Pyrimidine derivatives containing a functionalized side chain such as acetonyl, phenacyl, ethoxycarbonyl, or N-phenylcarbamoyl were synthesized by acylation of the pyrimidinylmethylides followed by desulfurization of the resulting pyrimidinylacylmethylides.

• 公益社団法人日本薬学会の論文
• 1981-10-25

著者

• 坂本 尚夫

  Pharmaceutical Institute, Tohoku University

• 山中 宏

  Pharmaceutical Institute, Tohoku University

• 今野 昌悦

  東北大学薬学部

• 今野 昌悦

  Pharmaceutical Institute, Tohoku University

• 新妻 節子

  Pharmaceutical Institute, Tohoku University

• 野地 さよ

  Pharmaceutical Institute, Tohoku University

• 坂本 尚夫

  Pharmaceutical Institute Tohoku University

• 新妻 節子

  Pharmaceutical Institute Tohoku University

• 野地 さよ

  Pharmaceutical Institute Tohoku University

関連論文

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• ピリミジン誘導体の研究(第42報)2,4-Dimethylthieno[2,3-d]pyrimidineの4位メチル基の反応性
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• Studies on Quinoline and Isoquinoline Derivatives. II. Coupling Reaction of Haloquinolines and Haloisoquinolines with Monosubstituted Acetylenes in the Presence of Palladium Complex
• Studies on Pyrimidine Derivatives. X. Coupling Reaction of 5-Halopyrimidines with Olefinic Compounds in the Presence of Palladium Acetate and Triphenylphosphine
• Studies on Pyrimidine Derivatives. IX. Coupling Reaction of Monosubstituted Acetylenes with Iodopyrimidines
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