Studies on Pyrimidine Derivatives. XIV. On the Structural Determination of Pyrimidine N-Oxides
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概要
- 論文の詳細を見る
N-Oxidation of pyrimidines having unsymmetrically substituted 4-and 6-positions with hydrogen peroxide in acetic acid gave mixture of their 1-oxides and 3-oxides. Ring transformation of these 1-oxides and 3-oxides into isoxazoles occurred on treatment with mineral acid, and provided information on the position of the N-oxide group in the pyrimidine N-oxides. Nuclear magnetic resonance spectroscopy with a lanthanide shift reagent was also found to be useful in identifying the pyrimidine 1-and 3-oxides.
- 公益社団法人日本薬学会の論文
- 1979-11-25
著者
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水柿 道直
Pharmaceutical Institute Tohoku University
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坂本 尚夫
Pharmaceutical Institute, Tohoku University
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山中 宏
Pharmaceutical Institute, Tohoku University
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新妻 節子
Pharmaceutical Institute, Tohoku University
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坂本 尚夫
Pharmaceutical Institute Tohoku University
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新妻 節子
Pharmaceutical Institute Tohoku University
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