Studies on Pyrimidine Derivatives. XL. : Ring Transformation of 4-Alkoxypyrimidine 1-Oxides by Reaction with Diketene

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概要

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• Treatment of 4-alkoxy-6-methylpyrimidine 1-oxides with acetic anhydride followed by reaction with diketene gave 7-acetyl-4-alkoxy-2-methylisoxazolo[4,5-c]pyridines and 7-acetyl-4-alkoxy-3-methyloxazolo[4,5-c]pyridines, respectively. The structure elucidation of these compounds on the basis of spectral data and chemical reactions, and the reaction pathway of the ring transformation are described.

• 公益社団法人日本薬学会の論文
• 1988-01-25

著者

• 坂本 尚夫

  Pharmaceutical Institute, Tohoku University

• 山中 宏

  Pharmaceutical Institute, Tohoku University

• 新妻 節子

  Pharmaceutical Institute, Tohoku University

• 坂本 尚夫

  東北大院薬

• 坂本 尚夫

  Pharmaceutical Institute Tohoku University

• 酒井 正美

  Pharmaceutical Institute Tohoku University

• 坂本 尚夫

  東北大学大学院薬学研究科

• 新妻 節子

  Pharmaceutical Institute Tohoku University

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