Studies on Quinoline and Isoquinoline Derivatives. VI. Addition Reaction of Diketene with Isoquinolines in the Presence of Carboxylic Acids
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概要
- 論文の詳細を見る
The addition reaction of diketene in formic, acetic or propionic acid to isoquinoline afforded 1-acetonyl-2-acyl-1,2-dihydroisoquinoline (II) in satisfactory yields. Though no reaction of this type was observed to occur in quinoline, isoquinoline-like N-heteroaromatic compounds such as phthalazine and 1,6-naphthyridine underwent similar addition reactions to give the corresponding dihydro-acetonyl compounds. The above product II was easily convertible to benzoquinolizine derivatives.
- 社団法人日本薬学会の論文
- 1981-04-25
著者
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坂本 尚夫
Pharmaceutical Institute, Tohoku University
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松田 ひとみ
Pharmaceutical Institute Tohoku University
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白石 隆幸
Pharmaceutical Institute, Tohoku University
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白石 隆幸
Laboratory Of Health Chemistry Niigata College Of Pharmacy
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坂本 尚夫
Pharmaceutical Institute Tohoku University
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