Condensed Heteroaromatic Ring Systems. XVI. : Synthesis of Pyrrolo[2,3-d]pyrimidine Derivatives

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概要

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• The synthesis of pyrrolo[2,3-d]pyrimidine derivatives was accomplished by the following two methods. One is the palladium-catalyzed reaction terminal acetylenes with N-(5-halo-4-pyrimidinyl)methanesulfonamides prepared by the nucleophilic substitution of 4-chloro-5-halopyrimidines with methanesulfonamide. The other is the photocyclization of 4-azidopyrimidines containing an olefinic function at the 5-position. The synthesis of 4-azidopyrimidine derivatives is also described.

• 社団法人日本薬学会の論文
• 1989-11-25

著者

• 渡辺 亮

  Pharmaceutical Institute Tohoku University

• 根東 義則

  Pharmaceutical Institute, Tohoku University

• 渡邊 亮

  Pharmaceutical Institute, Tohoku University

• 坂本 尚夫

  Pharmaceutical Institute, Tohoku University

• 山中 宏

  Pharmaceutical Institute, Tohoku University

• 根東 義則

  Graduate School Of Pharmaceutical Sciences Tohoku University

• 坂本 尚夫

  東北大院薬

• 坂本 尚夫

  Pharmaceutical Institute Tohoku University

• 坂本 尚夫

  東北大学大学院薬学研究科

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