Studies on Ketene and Its Derivatives. XLVI. Mass Spectrometric Studies of 3-Acetyl-4-hydroxy-6-methyl-1-pyridyl-2-pyridones and N-Pyridyl-2,6-dimethyl-4-pyrone-3-carboxamides

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概要

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• The reaction of diketene with amino-methylpyridines (Ia-i) was investigated, and the products were identified by the mass spectroscopic study. The reaction of 2-(Ia) and 3-amino-methylpyridines (Ib, d, f, h) with diketene gave the pyridone derivatives (IIIa, b, d, f, h), but 4-amino-methylpyridines (Ic, e, g, i) afforded the pyrone derivatives (IVc, e, g, i). The mass spectrum of III showed the characteristic peaks at m/e 243,215,187 and 175,and in the case of IV the strong peaks were observed at m/e 151,108,67 and 43. Each fragmentation pathways were discussed.

• 公益社団法人日本薬学会の論文
• 1972-01-25

著者

• 山中 宏

  Pharmaceutical Institute, Tohoku University

• 加藤 鉄三

  東北大学 薬

• 加藤 鉄三

  Pharmaceutical Institute Tohoku University

• 片桐 信弥

  Pharmaceutical Institute, Tohoku University

• 片桐 信弥

  Health Sci. Univ. Hokkaido Hokkaido Jpn

• 片桐 信弥

  Pharmaceutical Institute Tohoku University

• 増田 進一

  Pharmaceutical Institute, Tohoku University

• 増田 進一

  Pharmaceutical Institute Tohoku University

• 加藤 鉄三

  Pharmaceutical Institute. Tohoku University

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