Studies on Pyrimidine Derivatives. XXXVI. Reaction of 6-Substituted 2,4-Dimethylpyrimidines with Benzaldehyde in the Presence of Zinc Chloride
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概要
- 論文の詳細を見る
The condensation of 2,4 (2,6)-dimethylpyrimidines (7a-c), but not 6-methoxy-2,4-dimethylpyrimidine (7d), with benzaldehyde in the presence of zinc chloride occurred at the 4 (6)-methyl group predominantly. In contrast, the reaction of 7d under the same conditions gave 6-methoxy-4-methyl-2-styrylpyrimidine (17) as the main product. Similar site-selectivity in the oxidation of the dimethylpyrimidines with selenium dioxide was found.
- 公益社団法人日本薬学会の論文
- 1984-05-25
著者
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山中 宏
Pharmaceutical Institute, Tohoku University
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吉澤 博
Pharmaceutical Institute, Tohoku University
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坂本 尚夫
東北大院薬
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坂本 尚夫
Pharmaceutical Institute Tohoku University
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坂本 尚夫
東北大学大学院薬学研究科
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吉沢 博
Pharmaceutical Institute Tohoku University
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