Studies on Pyrimidine Derivatives. V. Reaction of 2,4-Dimethylazines with Ethyl Benzoate under Basic Conditions

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概要

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• Benzoylation of 2,4-dimethyl-(Ia), 2,4,6-trimethyl-pyrimidine (Ib), 2,4-dimethyl-quinazoline (Ic), 2,4-dimethyl-(Id), 2,4,6-trimethyl-pyridine (Ie), and 2,4-dimethyl-quinoline (If) with ethyl benzoate under basic conditions were performed. In analogy with the nitrosation with ethyl nitrite, methyl groups on the 4-position of IIa-f were preferentially benzoylated to give 4-phenacyl derivatives. Structures of all the products were determined by chemical derivatization.

• 公益社団法人日本薬学会の論文
• 1977-12-25

著者

• 山中 宏

  Pharmaceutical Institute, Tohoku University

• 阿部 弘之

  Pharmaceutical Institute Tohoku University

• 坂本 尚夫

  Pharmaceutical Institute Tohoku University

関連論文

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