Condensed Heteroaromatic Ring Systems. III. Synthesis of Naphthyridine Derivatives by Cyclization of Ethynylpyridinecarboxamides
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概要
- 論文の詳細を見る
Four kinds of naphthyridinones, i.e. 1,6-naphthyridin-5-one, 1,7-naphthyridin-8-one, 2,6-naphthyridin-2-one, and 2,7-naphthyridin-1-one derivatives, were commonly synthesized by the intramolecular cyclization of pyridinecarboxamides having an ethynyl group or β, β-dimethoxyethyl group adjacent to the carbamoyl group. The syntheses of the starting pyridine derivatives were easily accomplished by cross-coupling of the corresponding halopyridines with acetylenes.
- 1985-02-25
著者
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根東 義則
Pharmaceutical Institute, Tohoku University
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山中 宏
Pharmaceutical Institute, Tohoku University
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坂本 尚夫
東北大院薬
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坂本 尚夫
Pharmaceutical Institute Tohoku University
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坂本 尚夫
東北大学大学院薬学研究科
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