Electrical detection of Si-tagged Proteins on HF-last Si(100) and Thermally grown SiO_2 surfaces(Session5B: Emerging Devices III)

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概要

• 論文の詳細を見る

• we successfully detected silicon-binding proteins such as Si-tagged protein A, green fluorescent protein (GFP) and luciferase attached to OH-terminated SiO_2 and H-terminated Si surfaces by surface potential measurements using an AFM/Kelvin probe technique. We also observed significant change in electrical conductivity of lightly phosphorous doped poly-Si films after attachment of Si-tagged proteins. The conductivity of the poly-Si films is increased from 1.0×10^<-5>S/cm to 3.7×10^<-4>S/cm with the attachment of protein A. It is suggested that field effect passivation of unoccupied gap states in polycrystalline Si film increased the film conductivity. These results will open up the fabrication of a sensing device for locally ionized biomolecules.

• 社団法人電子情報通信学会の論文
• 2008-07-02

著者

• Miyazaki Seiichi

  Graduate School of Advanced Sciences of Matter, Hiroshima University

• Miyazaki S

  Hiroshima Univ. Higashi‐hiroshima Jpn

• Miyazaki Seiichi

  Dept. Of Electrical Engineering Hiroshima University

• Miyazaki Seiichi

  Faculty Of Engineering Hiroshima University

• MIYAZAKI S.

  Graduate School of Advanced Sciences of Matter, Hiroshima Univ.

• Higashi S.

  Graduate School of Advanced Sciences of Matter, Hiroshima University

• Miyazaki S

  Department Of Electrical Engineering Hiroshima University

• Miyazaki S

  Graduate School Of Advanced Sciences Of Matter Hiroshima University

• Mahboob S.

  Graduate School of Advanced Sciences of Matter, Hiroshima University

• Makihara K.

  Graduate School of Advanced Sciences of Matter, Hiroshima University

• Ikeda M.

  Graduate School of Advanced Sciences of Matter, Hiroshima University

• Kuroda A.

  Graduate School of Advanced Sciences of Matter, Hiroshima University

• Kaku H.

  Graduate School of Advanced Sciences of Matter, Hiroshima University

• Mahboob S.

  Graduate School Of Advanced Sciences Of Matter Hiroshima University

• Makihara K.

  Graduate School Of Advanced Sciences Of Matter Hiroshima University

• Higashi S.

  Graduate School Of Advanced Sciences Of Matter Hiroshima University

• Kohno A.

  Graduate School Of Advanced Sciences Of Matter Hiroshima University

• Ikeda M.

  Graduate School Of Advanced Sciences Of Matter Hiroshima University

• Kaku H.

  Graduate School Of Advanced Sciences Of Matter Hiroshima University

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