Isolated Small Rat Hepatocytes Express both Annexin III and Terminal Differentiated Hepatocyte Markers, Tyrosine Aminotransferase and Tryptophan Oxygenase, at the mRNA Level(Biochemistry/Molecular Biology)
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概要
- 論文の詳細を見る
We recently showed that annexin III is expressed in isolated small rat hepatocytes but, not in parenchymal hepatocytes. In the present study, we used reverse transcription polymerase chain analysis to examine the annexin III mRNA level in isolated small rat hepatocytes and parenchymal hepatocytes. Annexin III mRNA was detected in isolated small hepatocytes, but not in isolated parenchymal hepatocytes, confirming the presence of annexin III expression in isolated small rat hepatocytes at the mRNA level and indicating that the absence of annexin III expression in isolated parenchymal hepatocytes is due to the absence of annexin III mRNA. Furthermore, we examined the mRNA level of tyrosine aminotransferase and tryptophan oxygenase, two terminally differentiated hepatocyte markers. mRNA for these markers was detected in both parenchymal hepatocytes and small hepatocytes.
- 公益社団法人日本薬学会の論文
- 2004-11-01
著者
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Seki T
Institute Of Molecular And Cellular Biosciences University Of Tokyo
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HYUGA Masashi
Division of Biological Chemistry and Biologicals, National Institute of Health Sciences of Biologica
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Kawanishi T
Division Of Drugs National Institute Of Health Science
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Kawanishi Toru
Department Of Electronic Science And Engineering Kyoto Univerity
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Kawanishi Toru
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(present
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Seki Taiichiro
Department of Agricultural Chemistry, College of Agriculture and Veterinary Medicine, Nihon Universi
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Ariga Toyohiko
Department of Agricultural Chemistry, College of Agriculture and Veterinary Medicine, Nihon Universi
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Hyuga Masashi
Division Of Biological Chemistry And Biologicals National Institute Of Health Sciences
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HARASHIMA Mizuho
Department of Nutrition and Physiology, Nihon University College of Bioresource Sciences
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NIIMI Shingo
Division of Biological Chemistry and Biologicals, National Institute of Health Sciences
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Niimi S
Division Of Biological Chemistry And Biologicals National Institute Of Health Sciences
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Seki Taiichiro
Lab. Of Nutrition And Physiology Dep. Of Chemistry And Life Sci. Nihon Univ. Coll. Of Bioresource Sc
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Seki T
Department Of Nutrition And Physiology Nihon University College Of Bioresource Sciences
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Seki T
Nihon Univ. Coll. Of Bioresource Sci. Fujisawa Jpn
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Seki Taiichiro
Department Of Agricultural And Biological Chemistry College Of Agriculture And Veterinary Medicine N
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Seki Taiichiro
Laboratory Of Nutrition And Physiology Department Of Agricultural And Biological Chemistry Nihon Uni
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KOBAYASI TADASHI
Kobe Pharmaceutical University
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Hayakawa Takao
Div. Of Biological Chemistry And Biologicals National Inst. Of Health Sciences Jpn
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Hayakawa T
Division Of Biological Chemistry And Biologicals National Institute Of Health Sciences
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Hayakawa T
National Institute Of Health Sciences
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Kawanishi Toru
Division Of Drugs National Institute Of Health Science
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Kawanishi Toru
国立医薬品食品衛生研究所
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Ariga Toyohiko
Nihon Univ. Graduate School Of Applied Life Sciences
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Ariga Toyohiko
Department Of Agricultural And Biological Chemistry College Of Agriculture And Veterinary Medicine N
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Ariga Toyohiko
Department Of Agricultural And Biological Chemistry Nihon University College Of Bioresouce Sciences
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HAYAKAWA Takao
Deputy Director General, National Institute of Health Sciences
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関 敏美
Research Division Teikoku Hormone Manufacturing Co. Ltd.
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Hyuga Masashi
Department Of Nutrition And Physiology Nihon University College Of Bioresource Sciences
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Niimi Shingo
Division Of Biological Chemistry And Biologicals National Institute Of Health Sciences
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古林 隆司
宇部興産株式会社研究開発本部宇部研究所医薬研究部
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