New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles : Diversity in the Excitation-Contraction Mechanisms of the Heart
スポンサーリンク
概要
- 論文の詳細を見る
- 2009-03-20
著者
-
Nouchi Hideaki
Department Of Pharmacology Toho University Faculty Of Pharmaceutical Sciences
-
KAWANISHI Toru
Division of Biological Chemistry and Biologicals, National Institute of Health Sciences
-
TANAKA Hikaru
Department of Pharmacology, Toho University School of
-
SHIGENOBU Koki
Department of Pharmacology, Toho University School of
-
Tanaka Hikaru
Dep. Of Pharmacology Toho Univ. Fac. Of Pharmaceutical Sciences Jpn
-
Tanaka H
Department Of Pharmacology Toho University School Of Pharmaceutical Sciences
-
Kawanishi T
Division Of Drugs National Institute Of Health Science
-
Kawanishi Toru
Division Of Biological Chemistry And Biologicals National Institute Of Health Sciences
-
Shigenobu K
Department Of Pharmacology Toho University Faculty Of Pharmaceutical Sciences
-
Shigenobu K
Department Of Pharmacology Toho University School Of Pharmaceutical Sciences
-
Shigenobu Koki
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
-
Namekata Iyuki
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University
-
Takahara Akira
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University
-
Tanaka Hikaru
Dep. Of Pharmacology Fac. Of Pharmaceutical Sciences Toho Univ.
-
Tanaka Hikaru
Department Of Pharmacology Toho University Faculty Of Pharmaceutical Sciences
-
KOBAYASI TADASHI
Kobe Pharmaceutical University
-
Shigenobu Koki
Toho University School Of Pharmaceutical Sciences
-
Kawanishi Toru
Division Of Drugs National Institute Of Health Science
-
Kawanishi Toru
国立医薬品食品衛生研究所
-
Takahara Akira
Department Of Internal Medicine National Kawatana Hospital
-
古林 隆司
宇部興産株式会社研究開発本部宇部研究所医薬研究部
-
Tanaka Hikaru
Department Of Internal Medicine Sasebo Senjyu Hospital
-
Aikawa Tokiko
Department Of Pharmacology Toho University Faculty Of Pharmaceutical Sciences
-
Namekata Iyuki
Department Of Pharmacology Toho University Faculty Of Pharmaceutical Sciences
-
Tanaka Hikaru
Department Of Internal Medicine Hirosaki Municipal Hospital
-
Namekata Iyuki
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Toho University
-
Tanaka Hikaru
Department of Endocrinology and Metabolism, Hirosaki University
-
Takahara Akira
Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Toho University
関連論文
- Estrogen-like activity in Kampo medicines used for menopausal symptoms and gynecological diseases
- Blocking effect of NIP-142 on the KCNQ1/KCNE1 channel current expressed in HEK293 cells
- Effect of T-type and L-type Ca^2+ Channel Blockade on Early Phase Ca^2+ Transients in Rat Atrial and Ventricular
- Developmental Changes in Action Potential Prolongation by K+-Channel Blockers in Chick Myocardium
- Electrophysiological and Pharmacological Characteristics of Triggered Activity Elicited in Guinea-Pig Pulmonary Vein Myocardium
- The Novel Compounds That Activate Farnesoid X Receptor : the Diversity of Their Effects on Gene Expression
- Blocking Effect of NIP-142 on the KCNQ1/KCNE1 Channel Current Expressed in HEK293 Cells
- Membrane-Labeled MDCK Cells and Confocal Microscopy for the Analyses of Cellular Volume and Morphology(Molecular and Cell Biology)
- Lack of Action Potential-Prolonging Effect of Terfenadine on Rabbit Myocardial Tissue Preparations(Pharmacology)
- The Effects of Several Vasopressin Receptor Antagonists on Normal Intraocular Pressure and the Intraocular Distribution of Vasopressin Receptor Subtypes
- New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles : Diversity in the Excitation-Contraction Mechanisms of the Heart
- New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles: Diversity in the Excitation–Contraction Mechanisms of the Heart
- Species Difference in the Contribution of T-Type Calcium Current to Cardiac Pacemaking as Revealed by R(-)-Efonidipine
- OJ-071 Chronic Atrioventricular Block Abbreviated the Action Potential Duration of Canine Pulmonary Vein Myocardium(Arrythmia, basic(02)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Analysis of Arrhythmogenic Profile in a Canine Model of Chronic Atrioventricular Block by Comparing In Vitro Effects of the Class III Antiarrhythmic Drug Nifekalant on the Ventricular Action Potential Indices Between Normal Heart and Atrioventricular Bloc
- Muscarinic Receptor Subtypes Mediating Positive and Negative Inotropy in the Developing Chick Ventricle
- Atria Selective Prolongation by NIP-142, an Antiarrhythmic Agent, of Refractory Period and Action Potential Duration in Guinea Pig Myocardium
- New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles : Novel Approaches for the Diagnosis and Treatment of Cardiac Diseases
- MaxiK channel-triggered negative feedback system is preserved in the urinary bladder smooth muscle from streptozotocin-induced diabetic rats
- Histopathological Study of Kidney Abnormalities in an Experimental SIADH Rat Model and Its Application to the Evaluation of the Pharmacologic Profile of VP-343, a Selective Vasopressin V_2 Receptor Antagonist
- The Therapeutic Efficacy of VP-343,a Selective Vasopressin V_2 Receptor Antagonist, in the Experimental SIADH Rat Model
- Involvement of the Na^+/Ca^ Exchanger in the Automaticity of Guinea-Pig Pulmonary Vein Myocardium as Revealed by SEA0400
- Immunohistochemical Mucin Expression of Short-Segment Barrett's Esophagus
- Agonistic or antagonistic action of Kampo medicines used for menopausal symptoms on estrogen receptor subtypes, ERα and ERβ
- Preliminary Study for Sentinel Lymph Node Identification with Tc-99m Tin Colloid in Patients with Esophageal or Gastric Cancer
- The R(-)-Enantiomer of Efonidipine Blocks T-type but Not L-type Calcium Current in Guinea Pig Ventricular Myocardium
- Effect of Cilnidipine on L- and T-type Calcium Currents in Guinea Pig Ventricle and Action Potential in Rabbit Sinoatrial Node
- Elucidation With the Protease α-Chymotrypsin of the Inhibitory Modulating Action of Endogenous Neuropeptide Y Over Sympathetic Neurotransmission in Rat Vas Deferens
- Progressive systemic sclerosis associated with primary small cell carcinoma of the stomach
- P-42 Lack of Action Potential Prolonging Effect of Terfenadine on Myocardial Tissue Preparations.(Proceedings of the 27th Annual Meeting)
- Pathophysiological Significance of T-type Ca^ Channels : T-type Ca^ Channels and Drug Development
- Inhibition of Agonist-Induced Positive Inotropy by a Selective Rho-Associated Kinase Inhibitor, Y-27632
- Pharmacological Evidence for Involvement of Phospholipase D, Protein Kinase C, and Sodium-Calcium Exchanger in α-Adrenoceptor-Mediated Negative Inotropy in Adult Mouse Ventricle
- 糖タンパク質の質量分析
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. I. : Measurement of the amount of nitrosamine formed in rat and guinea pig stomachs.
- A Case of Superficial Esophageal Cancer Complicated with Idiopathic Muscular Hypertrophy of the Esophagus
- Thrombomodulin Enhances the Invasive Activity of Mouse Mammary Tumor Cells
- CYTOTOXICITY AND SUPPRESSION OF CALCIUM RESPONSE BY TRIBUTYLTIN-TREATMENT IN PRIMARY CULTURED HEPATOCYTES
- Direct toxicity of ethane-1, 2-dimethanesulfonate to rat epididymis
- Suppression of Calcium Response to Hormonal Stimulation by Tributyltin in Primary Cultured Rat Hepatocytes
- Involvement of Intracellular Ca^ in the Regulatory Volume Decrease After Hyposmotic Swelling in MDCK Cells
- Involvement of the Na^+/Ca^ Exchanger in Ouabain-Induced Inotropy and Arrhythmogenesis in Guinea-Pig Myocardium as Revealed by SEA0400
- Caspase Cascade Proceeds Rapidly After Cytochrome c Release From Mitochondria in Tumor Necrosis Factor-α-Induced Cell Death
- Quantitative Fluorescence Measurement of Cardiac Na^+/Ca^ Exchanger Inhibition by Kinetic Analysis in Stably Transfected HEK293 Cells
- Simultaneous Real-Time Detection of Initiator- and Effector-Caspase Activation by Double Fluorescence Resonance Energy Transfer Analysis
- Optical Bioimaging : From Living Tissue to a Single Molecule : Atrio-Ventricular Difference in Myocardial Excitation-Contraction Coupling : Sequential Versus Simultaneous Activation of SR Ca^ Release Units
- Effect of Manganese on Guinea Pig Ventricle : Initial Depression and Late Augmentation of Contractile Force
- Restricted Propagation of Cytoplasmic Ca^ Oscillation into the Nucleus in Guinea Pig Cardiac Myocytes as Revealed by Rapid Scanning Confocal Microscopy and Indo-1
- Pharmacological Profile of VP-343,a Novel Selective Vasopressin V_2 Receptor Antagonist, in Rats
- PLATELET ACTIVATING FACTOR : LACK OF DIRECT CARDIAC ACTION AND POSSIBLE TRANSMITTER RELEASE FROM CARDIAC SYMPATHETIC NERVE ENDINGS AT HIGH CONCENTRATIONS. ELECTROPHYSIOLOGICAL AND MECHANICAL STUDIES WITH GUINEA PIG VENTRICULAR MYOCARDIUM
- Glibenclamide-Sensitive Hypotension Produced by Helodermin Assessed in the Rat
- POTENTIATION BY BOVINE SERUM ALBUMIN (BSA) OF ENDOTHELIUM-DEPENDENT VASODILATOR RESPONSE TO ACETYL GLYCERYL ETHER PHOSPHORYLCHOLINE (AGEPC)
- Change in Annexin A3 Expression by Regulatory Factors of Hepatocyte Growth in Primary Cultured Rat Hepatocytes(Molecular and Cell Biology)
- Expression of Annexin A3 in Primary Cultured Parenchymal Rat Hepatocytes and Inhibition of DNA Synthesis by Suppression of Annexin A3 Expression Using RNA Interference(Biochemistry/Molecular Biology)
- Isolated Small Rat Hepatocytes Express both Annexin III and Terminal Differentiated Hepatocyte Markers, Tyrosine Aminotransferase and Tryptophan Oxygenase, at the mRNA Level(Biochemistry/Molecular Biology)
- Activins A, AB, and B Inhibit Hepatocyte Growth Factor Synthesis by MRC-5 Human Lung Fibroblasts
- LOSS OF VIABILITY AFTER DISULFIRAM TREATMENT WITHOUT PRECEDING DEPLETION OF INTRACELLULAR GSH
- ORIGIN AND CHARACTERISTICS OF FRESHLY ISOLATED RENAL CELLS OBTAINED BY PERFUSION OF COLLAGENASE IN VITRO
- COMPARISONS OF THE TOXICOKINETIC PARAMETERS IN RATS DETERMINED FOR LOW AND HIGH DOSE OF γ-CHLORDANE
- FETAL TOXICITY OF ZINC ETHYLPHENYLDITHIOCARBAMATE(ZEPC)(3). MECHANISM OF FORMATION OF METHEMOGLOBIN CAUSED BY ZEPC
- COMPARATIVE STUDY ON METABOLISM OF N-NITROSODIMETHYLAMINE AND N-NITROSOMETHYLBENZYLAMINE IN RAT LIVER
- RENAL MICROSOMAL N-NITROSODIMETHYLAMINE DEMETHYLASE DETERMINED BY A SENSITIVE RADIOMETRIC METHOD
- INFLUENCE OF DOSE ON THE TOXICOKINETICS OF γ-CHLORDANE
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. II. : Hepatotoxicity by the simultaneous administration of several drugs and nitrite.
- Endoscopic Screening for Esophageal Cancer in 788 Patients with Head and Neck Cancers
- 219 EFFECTS OF 2-MONOCHLORODIBENZOFURAN AND 3-MONOCHLORODIBENZOFURAN ON THE P450-MEDIATED DRUG METABOLIZING ENZYME ACTIVITIES OF PRIMARY CULTURED RAT HEPATOCYTES : COMPARISION WITH THE EFFECTS OF DIOXINS AND METHLCHOLANTHRENE
- A04 EFFECTS OF METYRAPONE ON THE CYTOCHROME P450 MEDIATED DRUG METABOLIZING ACTIVITIES IN THE PRIMARY CULTURES OF RAT HEPATOCYTES
- Blockade by NIP-142, an Antiarrhythmic Agent, of Carbachol-Induced Atrial Action Potential Shortening and GIRK1/4 Channel
- Comparison of the Inhibitory Effects of Docosahexaenoic Acid (DHA) on U46619-and Phenylephrine-Induced Contractions in Guinea-Pig Aorta(Pharmacology)
- Propagation of Normal and Abnormal Cytoplasmic Ca^ Oscillation into the Cell Nucleus in Cardiomyocytes
- β1-Subunit of MaxiK Channel in Smooth Muscle : a Key Molecule Which Tunes Muscle Mechanical Activity
- MaxiK Channel Mediates β_2-Adrenoceptor-activated Relaxation to Isoprenaline through cAMP-dependent and -independent Mechanisms in Guinea-pig Tracheal Smooth Muscle
- EFFECTS OF HYPOXIA AND REOXYGENATION ON TISSUE ATP LEVEL AND ELECTRICAL AND MECHANICAL FUNCTION OF ISOLATED GUINEA PIG VENTRICULAR MUSCLES.
- EFFECTS OF HYPOXIA AND METABOLIC INHIBITORS ON THE ELECTRICAL AND MECHANICAL ACTIVITIES OF ISOLATED GUINEA PIG PAPILLARY MUSCLES
- ELECTROPHYSIOLOGICAL EFFECTS OF A NEW ANTIARRHYTHMIC AGENT, LORCAINIDE, ON THE ISOLATED CARDIAC MUSCLE FIBER AS COMPARED WITH DISOPYRAMIDE
- Effect of NIP-142 on potassium channel α-subunits Kv1.5, Kv4.2 and Kv4.3, and mouse atrial repolarization
- Enhancement of Hepatocyte Growth Factor-Induced Cell Scattering in N-Acetylglucosaminyltransferase III-transfected HepG2 Cells(Biochemistry/Molecular Biology)
- NEGATIVE CHRONOTROPIC EFFECT OF DIBUTYRYL CYCLIC AMP ON THE CULTURED CHICK EMBRYONIC HEART CELLS AND THE PROLONGATION OF THE ACTION POTENTIAL DURATION
- Regulation of Inhibin β Chains and Follistatin mRNA Levels During Rat Hepatocyte Growth Induced by the Peroxisome Proliferator Di-n-butyl Phthalate
- Functional Contribution of Voltage-Dependent and Ca^2+-Activated K^+ (BK_ca) Channels to the Relaxation of Guinea-Pig Aorta in Response to Natriuretic Peptides
- Phospholipase C Inhibitors Suppress Spontaneous Mechanical Activity of Guinea Pig Urinary Bladder Smooth Muscle(Pharmacology)
- Studies on Vascular Endothelial Cell Damage by Polidocanol in Relation to Concentration, Ethylene-oxide Chain Length and Exposure Time
- POSSIBLE ROLE OF ENDOTHELIUM IN THE VASODILATOR RESPONSE OF RAT THORACIC AORTA TO PLATELET ACTIVATING FACTOR (PAF)
- STUDIES ON THE HYPOTENSIVE EFFECTS OF PLATELET ACTIVATING FACTOR (PAF, 1-o-ALKYL-2-ACETYL-sn-GLYCERYL-3-PHOSPHORYLCHOLINE) IN RATS, GUINEA PIGS, RABBITS, AND DOGS
- ELECTROPHYSIOLOGICAL AND MECHANICAL STUDIES ON THE CARDIAC EFFECTS OF A HISTAMINE H_2 RECEPTOR ANTAGONIST, CIMETIDINE, IN THE ISOLATED GUINEA PIG MYOCARDIUM
- EVIDENCE FOR A DIRECT ACTION OF X-537A ON THE CARDIAC PLASMA MEMBRANE AS AN IONOPHORE
- Simultaneous glycosylation analysis of human serum glycoproteins by high-performance liquid chromatography/tandem mass spectrometry
- CARDIOTONIC EFFECT OF PHTHALAZINOL (EG-626) IN THE ISOLATED GUINEA PIG MYOCARDIUM : MECHANICAL AND ELECTROPHYSIOLOGICAL STUDY
- Analysis of intracellular doxorubicin and its metabolites by ultra-high-performance liquid chromatography
- PLATELET ACTIVATING FACTOR ANALOGUES : LACK OF CORRELATION BETWEEN THEIR ACTIVITIES TO PRODUCE HYPOTENSION AND ENDOTHELIUM-MEDIATED VASODILATION
- CARDIAC EFFECTS OF KETANSERIN, A SEROTONIN ANTAGONIST : ELECTROPHYSIOLOGICAL EXAMINATIONS AS A PART OF TOXICITY STUDIES
- Quantitative Fluorescence Measurement of Cardiac Na+/Ca2+ Exchanger Inhibition by Kinetic Analysis in Stably Transfected HEK293 Cells
- Developmental Changes in Action Potential Prolongation by K^+-Channel Blockers in Chick Myocardium
- Electrophysiological and Pharmacological Characteristics of Triggered Activity Elicited in Guinea-Pig Pulmonary Vein Myocardium
- Electrophysiological Effects of the Class Ic Antiarrhythmic Drug Pilsicainide on the Guinea-Pig Pulmonary Vein Myocardium
- A new device for the determination of microsomal cytochrome P-450 in renal tissue preparations from various species contaminated with mitochondria and hemoglobin.
- Electrical Activity of the Mouse Pulmonary Vein Myocardium
- A New Approach to Characterization of Insulin Derived from Different Species Using 1H-NMR Coupled with Multivariate Analysis
- Spontaneous Oscillations of Cytoplasmic Free Calcium Ion Concentration in Cultured Smooth Muscle Cells from Guinea Pig Ileum.
- The Relationship between Spontaneous Calcium Oscillations and Cell Proliferation in Cultured Smooth Muscle Cells.