Immunohistochemical Mucin Expression of Short-Segment Barrett's Esophagus
スポンサーリンク
概要
- 論文の詳細を見る
Barrett's mucosa consists of metaplastic columnar epithelium (specialized columnar epithelium) of the esophagus. Recently, "short-segment Barrett's esophagus (SSBE)" was proposed. In the present study, we examined immunohistochemical mucin expression and the Ki-67 labeling index (LI) of SSBE, in 5-15 mm lengths. All 27 SSBE cases showed gastric mucin (MUC5AC, HGM, MUC6). CD10 and MUC2, which were markers of intestinal phenotypes, were detected in 13 (48.1%) and 14 (51.9%) of the 27 SSBE cases. Ki-67 LI of SSBE positive cases for CD10 was 23.6%, while that of SSBE negative cases for CD10 was 14.4% (p<0.05). SSBE cases were divided into two groups: one was gastric epithelium type with low Ki-67 LI, and the other was metaplastic epithelium with intestinal metaplasia and high Ki-67 LI. The latter group was suggested to be more important as a premalignant lesion of esophageal adenocarcinoma.
- 東海大学の論文
著者
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Kawabe Mayumi
Dims Institute Of Medical Science
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HARA Tadashi
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine
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MAKUUCHI HIROYASU
Department of Cardiovascular Surgery, Tokai University Hospital
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Yasuda S
Himedic Imaging Center At Lake Yamanaka
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Yasuda Seiei
東海大学 医学部外科学
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Yasuda Seiei
Department Of Surgery Tokai University School Of Medicine
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Kijima Hiroshi
東海大学 医学部内科学
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TANAKA Hikaru
Department of Pharmacology, Toho University School of
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Kijima H
Tokai Univ. School Of Medicine Kanagawa Jpn
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Hara Tadashi
Department Of Surgery Tokai University School Of Medicine
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Tanaka Hikaru
Department Of Surgery Tokai University School Of Medicine
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Kawada Hiroshi
Department Of Hematology/oncology Tokai University School Of Medicine
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Kijima Hiroshi
Department Of Pathology Tokai University School Of Medecine
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CHINO Osamu
Department of Surgery, Tokai University School of Medicine
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YAMAMOTO Soichiro
Department of Surgery, Tokai University School of Medicine
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Tanaka Hikaru
Department Of Pharmacology Toho University Faculty Of Pharmaceutical Sciences
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Yasuda Seiei
Himedic Imaging Center At Lake Yamanaka Keio University School Of Medicine
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Hara Tadashi
Department Of Chemical Engineering And Materials Sciences Faculty Of Engineering Doshisha University
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Hara T
Tokai Univ. School Of Medicine
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SHIMADA HIDEO
Department of Surgery, Tokai University School of Medicine
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KISE YOSHIFUMI
Department of Surgery, Tokai University School of Medicine
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KENMOCHI TAKAHIRO
Department of Surgery, Tokai University School of Medicine
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KIJIMA Hiroshi
Pathology, Tokai University School of Medicine
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TANAKA Makiko
Critical Care and Emergency Medicine, Tokai University School of Medicine
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INOKUCHI Sadaki
Critical Care and Emergency Medicine, Tokai University School of Medicine
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Shimada Hideo
Department Of Surgery Tokai University School Of Medicine
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Makuuchi Hiroyasu
Department Of Surgery School Of Medicine Tokai University
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Makuuchi Hiroyasu
Department Of Cardiovascular Surgery Tokai University Hospital
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Hirabayashi Kenichi
Department Of Pathology Tokai University School Of Medicine
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Hara Tatsuru
Department Of Surgery Tokai University School Of Medicine
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Chino O
Department Of Surgery Tokai University School Of Medicine
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Tanaka Motonao
Critical Care And Emergency Medicine Tokai University School Of Medicine
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Machimura Takao
Second Department Of Surgery Tokai University School Of Medicine
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Makuuchi H
Department Of Surgery School Of Medicine Tokai University
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Yokoyama Seishichi
Department Of Pediatric Surgery Gastrointestinal Surgery And Radiology Tokai University School Of Me
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Kise Yoshifumi
Department Of Surgery Tokai University School Of Medicine
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Shimada Hideo
Department Of Biochemistry Keio University
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Murakami T
Department Of Critical Care And Emergency Medicine Tokai University School Of Medicine
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Inokuchi Sadaki
Department Of Critical Care And Emergency Medicine Tokai University School Of Medicine
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Kenmochi Takahiro
Department Of Surgery Hiratsuka City Hospital
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Kijima Hiroshi
Department Of Hematology/oncology Tokai University School Of Medicine
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Maruyama H
Department Of Surgery Tokai University School Of Medicine
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Yamamoto Soichiro
Department Of Gastroenterology Kure Kyosai Hospital
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Tanaka Hikaru
Department Of Internal Medicine Sasebo Senjyu Hospital
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Kawada Hiroshi
Research Center For Genetic Engineering And Cell Transplantation
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Yamamoto Sohichirou
Department Of Surgery Tokai University School Of Medicine
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Tanaka Hikaru
Department Of Internal Medicine Hirosaki Municipal Hospital
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Tanaka Hikaru
Department of Endocrinology and Metabolism, Hirosaki University
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ASAMOTO Makoto
Department of Surgery, Tokai University School of Medicine
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Kawabe Mayumi
Department of Surgery, Tokai University School of Medicine
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