Relationship between gastric mucosal IL-8 levels and histological gastritis in patients with Helicobacter pylori infection

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概要

• 論文の詳細を見る

• To determine the role of host immune responses in H. pylori infection, we examined the relationship between gastric mucosal IL-8 levels and histological gastritis in patients with H. pylori infection. Biopsy tissue obtained from 99 patients were homogenized and mucosal IL-8 levels measured by ELISA. The gastric mucosal IL-8 levels in both the antrum and corpus were higher in patients with H. pylori than in H. pylori negative patients. IL-8 levels in the corpus but not the antrum correlated with the severity of the atrophy. The IL-1B polymorphism had no influence on the degree of IL-8 production. These findings indicate that IL-8 production is independent of IL-1B polymorphisms and IL-8 may play an important role in the development of atrophic gastritis.

• 東海大学の論文

著者

• OGAWA Yoshiaki

  Department of Hematology and Oncology, Tokai University School of Medicine

• Kijima Hiroshi

  Department of Pathology, Hirosaki University School of Medicine

• Takagi Atsushi

  Department Of Cardiology Tokyo Women's Medical University

• Ogawa Yoshiaki

  Department Of Hematology And Oncology Tokai University School Of Medicine

• Ogawa Yoshiaki

  Department Of Internal Medicine Tokai University School Of Medicine

• Ogawa Yoshiaki

  東海大学 医学部内科学

• OZAWA Hideki

  Department of Physics, Osaka University

• Kijima Hiroshi

  東海大学 医学部内科学

• Kijima H

  Tokai Univ. School Of Medicine Kanagawa Jpn

• YANAGI Hidetaka

  Department of Internal Medicine, Tokai University School of Medicine

• KOJIMA Seiichiro

  Department of Internal Medicine, Tokai University School of Medicine

• URANO Tetsuya

  Department of Internal Medicine, Tokai University School of Medicine

• XUAN Jiang

  Department of Infectious disease, Tokai University School of Medicine

• DEGUCHI Ryuzo

  Department of Internal Medicine, Tokai University School of Medicine

• FUKUDA Ryuuki

  Department of Internal Medicine, Tokai University School of Medicine

• NISHINA Makoto

  Department of Internal Medicine, Tokai University School of Medicine

• SUDO Hiroshi

  Department of Internal Medicine, Tokai University School of Medicine

• KOGA Yasuhiro

  Department of Infectious disease, Tokai University School of Medicine

• Fukuda Ryuuki

  Department Of Internal Medicine Tokai University School Of Medicine

• Fukuda Ryuki

  The Fourth Department Of Internal Medicine School Of Medicine Tokai University

• Urano Tetsuya

  Department Of Internal Medicine Tokai University School Of Medicine

• Urano T

  Department Of Medicine Tokai University School Of Medicine

• Urano Tetsuya

  Department Of Medicine Tokai University School Of Medicine

• Kawada Hiroshi

  Department Of Hematology/oncology Tokai University School Of Medicine

• Kijima Hiroshi

  Department Of Pathology Tokai University School Of Medecine

• Kojima Seiichiro

  Department Of Internal Medicine Tokai University School Of Medicine

• Kojima Seiichiro

  Tokai University School Of Medicine

• Takagi Atsushi

  Department Of Internal Medicine Tokai University School Of Medicine

• Ozawa Hideki

  Department Of Internal Medicine Tokai University School Of Medicine

• Yanagi Hidetaka

  Department Of Internal Medicine Tokai University School Of Medicine

• Hirabayashi Kenichi

  Department Of Pathology Tokai University School Of Medicine

• Takagi Atsushi

  Department Of General Internal Medicine Tokai University School Of Medicine

• Sudo Hiroshi

  Department Of Internal Medicine Tokai University School Of Medicine

• Xuan Jiang

  Department Of Infectious Disease Tokai University School Of Medicine

• Koga Yasuhiro

  Department Of Infections Disease Tokai University School Of Medicine

• Koga Yasuhiro

  Department Of Infectious Disease Tokai University School Of Medicine

• Deguchi Ryuzo

  Department Of Internal Medicine Tokai University School Of Medicine

• Nishina Makoto

  Department Of Internal Medicine Tokai University School Of Medicine

• Ozawa Hideki

  Department Of Earth And Space Science Graduate School Of Science Osaka University

• Kijima Hiroshi

  Department Of Hematology/oncology Tokai University School Of Medicine

• Takagi Atsushi

  Department Of Cardiology The Heart Institute Of Japan Tokyo Women's Medical University

• Ozawa Hideki

  Department Of Cardiology Tokai University School Of Medicine

• Kawada Hiroshi

  Research Center For Genetic Engineering And Cell Transplantation

• Ogawa Yoshiaki

  Division Of Hematology/oncology Department Of Internal Medicine Tokai University School Of Medicine

• Yanagi Hidetaka

  Department Of General Internal Medicine Tokai University School Of Medicine

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