Menaquinone-4 Production by a Sulfonamide-resistant Mutant of Flavobacterium sp. 238-7(Microbiology & Fermentation Industry)

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概要

• 論文の詳細を見る

• Sulfonamide-resistant mutant strains were derived from a mutant strain, K_3-15, of Flavobacterium sp. 238-7 to improve the menaquinone (MK)-4 productivity. A mutant strain, SP0736, with resistance to 50μg/l of sulfapyridine in a chemically-defined medium, had improved productivity of MK-4. By optimization of the culture conditions, the mutant strain SP0736 produced 280mg/l of the culture broth (240mg/l of MK-4 and 40mg/l of MK-6) at 6 days of cultivation. The productivity of strain SP0736 was 50% higher than that of the parent strain, K_3-15.

• 社団法人日本農芸化学会の論文
• 1989-11-23

著者

• Taguchi H

  Department Of Bioresource Development Hiroshima Prefectural University

• Tani Y

  Graduate School Of Biological Sciences Nara Institute Of Science And Technology:department Of Biosci

• Shibata Tohru

  Department Of Agricultural Chemistry Faculty Of Agriculture Kyoto University

• Duangmanee Chiranun

  Research Center For Cell And Tissue Culture Faculty Of Agriculture Kyoto University

• Tani Yoshiki

  Research Center For Cell And Tissue Culture Faculty Of Agriculture Kyoto University

• TAGUCHI Hisataka

  Research Center for Cell and Tissue Culture, Faculty of Agriculture, Kyoto University

• SHIBATA Takashi

  Research Center for Cell and Tissue Culture, Faculty of Agriculture, Kyoto University

• Tani Yoshiki

  Research Center For Cell And Tissue Cluture Faculty Of Agriculture Kyoto University

• Taguchi Hisataka

  Research Center For Cell And Tissue Culture Faculty Of Agriculture Kyoto University

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