Biochemical Characterization of an L-Methionine-Enriched Mutant of a Methylotrophic Yeast, Candida boidinii
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概要
- 論文の詳細を見る
The effects of an ethionine-resistant mutation in a methylotrophic yeast, Candida boidinii, were studied. In mutant strain E500-78 (ethionine-resistant), SAM synthetase activity was low and was only slightly repressed by L-methionine. Formyltetrahydrofolate synthetase and serine hydroxymethyltransferase were involved in synthesis of the methyl group of L-methionine. The activities of the methyl group transferring enzymes and homocysteine transmethylation were repressed by L-methionine in the wild type strain, but not in the mutant. The activities of the methyl group transferring enzymes were markedly stimulated when the mutant was grown in methanol medium.
- 社団法人日本生物工学会の論文
- 1990-05-25
著者
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Lim W‐j
Kyoto Univ. Kyoto Jpn
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TANI Yoshiki
Research Center for Cell and Tissue Culture, Faculty of Agriculture, Kyoto University
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Yang Han-chul
Institute Of Biotechnology Korea University
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LIM WANG-JIN
Research Center for Cell and Tissue Culture, Faculty of Agriculture, Kyoto University
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Lim Wang-jin
Research Center For Cell And Tissue Culture Faculty Of Agriculture Kyoto University
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Tani Yoshiki
Research Center For Cell And Tissue Cluture Faculty Of Agriculture Kyoto University
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