Determination of Cyanide and Thiocyanate in Sugihiratake Mushroom Using HPLC Method with Fluorometric Detection
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概要
- 論文の詳細を見る
A novel type of encephalopathy occurred in patients with chronic kidney diseases, which was associated with the ingestion of the Sugihiratake mushroom during the fall of 2004 in Japan. We attempted to investigate whether cyanide and thiocyanate are present in the Sugihiratake samples and determined the cyanide and thiocyanate levels in fifteen samples collected from different Japanese districts using HPLC with fluorometric detection. The cyanide ions and thiocyanate ions were detected in the ranges of N.D.-114.0 and N.D.-17.0μg/g in the samples, respectively. This is the first study to quantitatively detect cyanide and thiocyanate in the Sugihiratake mushrooms. This result demonstrated that cyanide exposure could occur from the intake of Sugihiratake mushrooms in one's diet. Furthermore, we discussed the possible association between cyanide and the onset of encephalopathy.
- 社団法人日本薬学会の論文
- 2006-02-01
著者
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Maitani Tamio
国立医薬品食品衛生研究所
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Maitani Tamio
National Institute of Health Sciences
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AMAKURA Yoshiaki
National Institute of Health Sciences
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KONDO Kazunari
National Institute of Health Sciences
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AKIYAMA Hiroshi
National Institute of Health Sciences
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Maitani Tamio
Division of Foods, National Institute of Health Sciences
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Kondo Kazunari
National Inst. Of Health Sciences
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Maitani T
Division Of Foods National Institute Of Health Sciences
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KITTA Kazumi
National Food Research Institute
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Toida Toshihiko
Graduate School of Pharmaceutical Sciences, Chiba University
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Sakai Shinobu
Graduate School of Pharmaceutical Sciences, Chiba University
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Sugita-Konishi Yoshiko
National Institute of Health Sciences
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Saito Shin
S-BIO Development Department, Sumitomo Bakelite Co.
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Kitta Kazumi
National Food Res. Inst.
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Sakai Shinobu
National Inst. Of Health Sciences
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Amakura Yoshiaki
Department Of Pharmacognosy College Of Pharmaceutical Sciences Matsuyama University
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Machiguchi Takahisa
Faculty Of Science Saitama University
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Maitani Tamio
National Institute For Environmental Studies
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Sakai Shinobu
Sumitomo Bakelite Co. Ltd.
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Sakai Shinobu
Graduate School Of Pharmaceutical Sciences Chiba University
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Sakai Shinobu
Research Associate Department Of Architectural Engineering Hokkaido University
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Sugita-konishi Yoshiko
National Inst. Of Health Sciences
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米谷 民雄
Division Of Foods National Institute Of Health Sciences
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Toida Toshihiko
Graduate School Of Pharmaceutical Sciences Chiba University
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Sakai Yumiko
Nagahama Institute For Biochemical Science Oriental Yeast Co. Ltd.
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Akiyama Hiroshi
Division Of Novel Foods And Immunochemistry National Institute Of Health Science
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Sakai Yumiko
National Inst. Of Health Sciences
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Akiyama Hiroshi
National Food Research Institute National Agriculture And Food Research Organization
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Kondo Kazunari
National Food Research Institute, National Agriculture and Food Research Organization
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