Triterpenoid Saponins from the Roots of Sophora koreensis
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概要
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From the roots of Sophora koreensis (Fabaceae), three new oleanene-type triterpene glycosides, echinosophorosides A_1 (1) and B (2), and acetyl-subproside II (5), were isolated as their methyl esters, together with the four known ones sophoraflavoside I, kudzusaponin SA_3, subproside II, and azukisaponin V. The structures of the new saponins were elucidated to be 3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl(1→2)-β-D-glucuronopyranosyl kudzusapogenol A 22-O-α-L-arabinopyranoside (1), 3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl-(1→2)-)β-D-glucuronopyranosyl abrisapogenol C 22-O-α-L-arabinopyranoside (2), and 3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl(1→2)-β-D-glucuronopyranosyl kudzusapogenol A 22-O-acetate (5), respectively. It is noteworthy that two arabinopyranosyl moieties in the same molecule, echinosophoroside B (2), have different conformations. The conformation of the arabinopyranosyl moiety existing in the trisaccharide moiety was determined to be ^1C_4, whereas that of the arabinopyranosyl unit at C-22 was identified as ^4C_1.
- 2004-07-01
著者
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CHANG Hyeun
College of Pharmacy, Yeungnam University
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Kim Ju
Natural Products Research Institute And College Of Pharmacy Seoul National University
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BAE KiHwan
College of Pharmacy, Chungnam National University
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Kim Hyun
College Of Pharmacy Kangwon National University
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SON Kun
Department of Food Nutrition, Andong National University
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KANG Sam
Natural Products Institute, Seoul National University
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BYUN Ji
Natural Products Research Institute and College of Pharmacy, Seoul National University
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BAE Ki
College of Pharmacy, Chungnam National University
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Byun Ji
Natural Products Research Institute And College Of Pharmacy Seoul National University
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Bae Ki
College Of Pharmacy Chungnam National University
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Bae Kihwan
韓国
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Kim Jin
韓国
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Son K
Department Food & Nutriton Andong National University
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Son Jong
Coll. Of Pharmacy Yeungnam Univ.
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Chang Hyeun
College Of Pharmacy Yeungnam University
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Kang Sam
韓国
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Kang Sam
Natural Products Research Institute And College Of Pharmacy Seoul National University
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Kang Sam
Natural Product Research Institute Seoul National University
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Bae Kihwan
College Of Pharmacy Chungnam National University
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Chang Hyeun
Coll. Of Pharmacy Yeungnam Univ.
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Son Kun
Department Food & Nutriton Andong National University
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Kang S
Natural Products Research Institute And College Of Pharmacy Seoul National University
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Kim Ju
Natural Products Res. Inst. And Coll. Of Pharmacy Seoul National Univ.
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Chang H
College Of Pharmacy Yeungnam University
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Kim Hyun
College Of Pharmacy And Research Institute Of Drug Development Chonnam National University
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Bae K
College Of Pharmacy Chungnam National University
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Kim Hyun
College Of Electrical & Computer Engineering Chungbuk National University
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