Caffeic Acid Protects Hydrogen Peroxide Induced Cell Damage in WI-38 Human Lung Fibroblast Cells(Molecular and Cell Biology)

スポンサーリンク

概要

• 論文の詳細を見る

• Cytoprotective effect of caffeic acid (3,4-dihydroxy cinnamic acid) on human lung fibroblast (WI-38) cells against hydrogen peroxide induced damage was investigated. Caffeic acid was found to scavenge intracellular reactive oxygen species, and 1,1-diphenyl-2-picrylhydrazyl radical, and thus prevented lipid peroxidation. The caffeic acid protected cell damage of WI-38 cells exposed to hydrogen peroxide (H_2O_2), via the activation of extracellular signal regulated kinase protein. Caffeic acid increased the activity of catalase and its protein expression. Hence, from the present study, it is suggestive that caffeic acid protects WI-38 cells against H_2O_2 damage by enhancing the cellular antioxidant activity.

• 社団法人日本薬学会の論文
• 2006-09-01

著者

• Kim Ju

  Natural Products Research Institute And College Of Pharmacy Seoul National University

• ZHANG Rui

  Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine

• KIM Jin

  Departments of Surgery, Seoul National University College of Medicine

• Kim Jin

  韓国

• Son Jong

  Coll. Of Pharmacy Yeungnam Univ.

• Lee Kyoung

  Department Of Biochemistry College Of Medicine And Applied Radiological Science Research Institute C

• Kang Kyoung

  School Of Medicine And Applied Radiological Science Research Institute Cheju National University

• YOU Ho

  Dppartment of Pharmacology, College of Medicine, Chosun University

• KANG Kyoung

  Department of Biochemistry, College of Medicine and Applied Radiological Science Research Institute,

• HYUN Jin

  Department of Biochemistry, College of Medicine and Applied Radiological Science Research Institute,

• PIAO Meijing

  Department of Biochemistry, College of Medicine and Applied Radiological Science Research Institute,

• CHAE Sungwook

  Department of Biochemistry, College of Medicine and Applied Radiological Science Research Institute,

• KIM Kil

  Department of Food Science and Technology, Cheju National University

• JEON You

  Department of Food Science and Technology, Cheju National University

• PARK Doek

  Department of Histology, College of Medicine, Cheju National University

• YOU Ho

  Department of Pharmacology, College of Medicine, Chosun University

• Kim Kil

  Department Of Agronomy College Of Agriculture Kyungpook National University

• Hyun Jin

  School Of Medicine And Applied Radiological Science Research Institute Cheju National University

• You Ho

  Dppartment Of Pharmacology College Of Medicine Chosun University

• You Ho

  Department Of Pharmacology College Of Medicine Chosun University

• Jeon You

  Department Of Food Science And Technology Cheju National University

• Kim Jin

  Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar

• Chae Sungwook

  Department Of Biochemistry College Of Medicine And Applied Radiological Science Research Institute C

• Piao Meijing

  School Of Medicine And Applied Radiological Science Research Institute Cheju National University

• Zhang Rui

  School Of Medicine And Applied Radiological Science Research Institute Cheju National University

• Zhang Rui

  Department Of Cardiology Rui Jin Hospital Shanghai Jiao Tong University School Of Medicine

• Park Doek

  Department Of Histology College Of Medicine Cheju National University

• Chae S

  Department Of Biochemistry College Of Medicine And Applied Radiological Science Research Institute C

• Hyun Jin

  Department Of Biochemistry College Of Medicine Cheju National University

• Zhang Rui

  Department Of Biology The Pennsylvania State University

• Kim Kil

  Department Of Agronomy College Of Agriculture And Life Sciences Kyungpook National University

• Zhang Rui

  Department Of Biochemistry And Molecular Biology Fourth Military Medical University

• KANG Kyoung

  College of Medicine, Jeju National University

関連論文

• Partial vs Full Coverage for Tandem Lesions in Culprit Vessel During Primary Coronary Intervention in Patients With Acute ST-Elevation Myocardial Infarction : The PERFECT-AMI Study
• Ochnaflavone, Naturally Occurring Biflavonoid, Inhibits Phospholipase A_2 Dependent Phosphatidylethanolamine Degradation in a CCl_4-Induced Rat Liver Microsome(Biochemistry)
• Anti-asthmatic Activity of an Ethanol Extract from Saururus chinensis(Biochemistry)
• Ginkgetin, a Biflavone from Ginko biloba Leaves, Inhibits Cyclooxygenases-2 and 5-Lipoxygenase in Mouse Bone Marrow-Derived Mast Cells(Biochemistry)
• Saponins and Other Constituents from the Leaves of Aralia elata
• Antiinflammatory Activity of Astilbic Acid from Astilbe chinensis(Biochemistry/Molecular Biology)
• Triterpenoid Saponins from the Roots of Sophora koreensis
• Phenolic Glycosides from Pyrola japonica
• Inhibitory Effects of Nardostachin on Nitric Oxide, Prostaglandin E_2, and Tumor Necrosis Factor-α Production in Lipopolysaccharid Activated Macrophages(Biochemistry/Molecular Biology)
• Microsatellite instability and Epstein-Barr virus infection in gastric remnant cancers
• Flavan-3-ols Having a γ-Lactam from the Roots of Actinidia arguta Inhibit the Formation of Advanced Glycation End Products in Vitro
• Anthraquinones from the Seeds of Cassia tora with Inhibitory Activity on Protein Glycation and Aldose Reductase(Pharmacognosy)
• Puerariafuran, a New Inhibitor of Advanced Glycation End Products (AGEs) Isolated from the Roots of Pueraria lobata
• Dual Inhibition of Cyclooxygenases-2 and 5-Lipoxygenase by Deoxypodophyllotoxin in Mouse Bone Marrow-Derived Mast Cells(Biochemistry/Molecular Biology)
• Inhibition of Nitric Oxide and Tumor Necrosis Factor-α (TNF-α) Production by Propenone Compound through Blockade of Nuclear Factor (NF)-κB Activation in Cultured Murine Macrophages (Biochemistry/Molecular Biology)
• Perifollicular Fibrosis : Pathogenetic Role in Androgenetic Alopecia(Biochemistry)
• Genome-wide identification of chemosensitive single nucleotide polymorphism markers in colorectal cancers
• Fast Verification of Hash Chains with Reduced Storage
• Asterosaponins Isolated from the Starfish Asterias amurensis
• Pharmacokinetics of Indomethacin, a Metabolite of Acemetacin, Following a Single dose and Multiple doses Administered as Acemetacin Sustained-Release Tablets in Healthy Male Volunteers
• Possible role for a polysaccharide antigen shared between Streptococcus pyogenes and S. mutans in the pathogenesis of poststreptococcal glomerulonephritis
• OSTEOLYSIS OF THE DISTAL CLAVICLE IN THE ELITE ROCK CLIMBER : A CASE REPORT(Proceedings of The 8^ Asian Federation of Sports Medicine Congress 2005 Tokyo)
• Efficacy of Whole Brain Radiotherapy Combined with Fractionated Stereotactic Radiotherapy in Metastatic Brain Tumors, and Prognostic Factors
• Cytoprotective Effects of KIOM-79 on Streptozotocin Induced Cell Damage by Inhibiting ERK and AP-1(Highlighted paper selected by Editor-in-chief,Biochemistry)
• Caffeic Acid Protects Hydrogen Peroxide Induced Cell Damage in WI-38 Human Lung Fibroblast Cells(Molecular and Cell Biology)
• Protective Effect of Triphlorethol-A from Ecklonia cava against Ionizing Radiation in vitro
• Cytotoxic Effect of 7β-Hydroxycholesterol on Human NCI-H460 Lung Cancer Cells(Molecular and Cell Biology)
• Protective Effect of Puerariae Radix on Oxidative Stress Induced by Hydrogen Peroxide and Streptozotocin(Molecular and Cell Biology)
• Antioxidant Activity of Jionoside D from Clerodendron trichotomum(Biochemistry/Molecular Biology)
• Detection of recurrent cervical intraepithelial neoplasia by HPV test after LEEP conization(Oncology 8)
• Two New Cycloartane Saponins from the Roots of Astragalus membranaceus
• Microscale Metal Patterning Using Photosensitive Silver Organometallic Compounds
• Effect of Physical Exercise on Renal Response to Head-Out Water Immersion
• Individual tumorigenesis pathways of sporadic colorectal adenocarcinomas are associated with the biological behavior of tumors
• Triterpenoid Saponins from the Seeds of Pharbitis nil
• Aldose Reductase Inhibitors from the Fruiting Bodies of Ganoderma applanatum(Pharmacognosy)
• Norditerpenoid Alkaloids from the Processed Tubers of Aconitum carmichaeli
• A New Acylated Triterpene from the Roots of Chaenomeles japonica
• 24-nor-Ursane Type Triterpenoids from the Stems of Rumex japonicus
• Impedance Spectra near the Phase Transition Temperature of Potassium Lithium Niobate Crystals
• Expressional Changes of Neuropeptide Y and Cholecystokinin in the Arcuate and Paraventricular Nuclei after Capsaicin Administration
• Developmental Characteristics of Mice Lacking the DNA Excision Repair Gene XPG
• Neuronal Migration and Neuronal Migration Disorder in Cerebral Cortex
• P1-IS-95 Comparision of selective uterine artery ligation and blunt uterine artery coagulation in total laparoscopic hysterectomy
• Influence of Extracellular Na^+ Removal on Cytosolic Ca^ Concentration in Smooth Muscle Cells of Rabbit Cerebral Artery
• O-2-63 Transgastric Endoscopic Cholecystectomy of the Porcine Model
• Cyclooxygenase-2 Inhibitory Cerebrosides from Phytolaccae Radix
• Dual-Phase Metallic Glass and its Two-Dimensional Fractal Morphology(Cross-disciplinary Physics and Related Areas of Science and Technology)
• Carcinoma of the External Auditory Canal and Middle Ear : Staging and Management Dilemma
• Increased Serum Glycated Albumin Level is Associated With the Presence and Severity of Coronary Artery Disease in Type 2 Diabetic Patients
• Topic Document Model Approach for Naive Bayes Text Classification(Natural Language Processing)
• Diffuse Phase Transition in Potassium Lithium Niobate Ferroelectric Crystals : Condensed Matter Electronic Properties, etc.
• Study on Energy Band of InGaN/GaN Self-Assembled Quantum Dots by Deep-Level Transient Spectroscopy
• Inhibitory Effect of TNF-α and IL-8 Secretion by Pimarane-Type Diterpenoids from Acanthopanax koreanum
• Al-Induced Crystallization of an Amorphous Si Thin Film in a Polycrystalline Al/Native SiO_2/Amorphous Si Structure
• Changes of psychiatric parameters and their relationships by oral isotretinoin in acne patients
• Family and segregation studies : 411 Chinese children with primary nocturnal enuresis
• Preparation and application of a new modified liquid chromatographic chiral stationary phase based on (+)-(18-crown-6)-2, 3, 11, 12-tetracarboxylic acid
• Measurement of extent of bone ongrowth and hydroxyapatite absorption in retrieved acetabular cups
• The effect of stabilizing layer on the SNR and thermal stability in the strongly coupled AFC media by micromagnetics simulation (マルチメディアストレージ 第6回アジア情報記録技術シンポジウム〔英文〕)
• The effect of stbilizing layer on the SNR and thermal stability in the strongly coupled AFC media by micromagnetics simulation
• Sarcoptes scabiei in Infundibulum of Nodular Scabies
• The transmembrane tyrosine of μ-heavy chain is required for BCR destabilization and entry of antigen into clathrin-coated vesicles
• Identification and characterization of Paragonimus westermani leucine aminopeptidase
• 1.55 μm Wavelength Strain-Compensated In_χGa_As/In_yAl_As Electroabsorption Modulators with High Extinction Ratio and Low Polarization-Dependent Loss
• Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System and Angiotensin II Type 1-Receptor Activating Antibodies in Renal Rejection
• Differential Control of Systolic and Diastolic Blood Pressure : Factors Associated With Lack of Blood Pressure Control in Rural Community of Liaoning Province, China
• A genetic mouse model carrying the nonfunctional xeroderma pigmentosum group G gene
• Family-based association study between GRIK2 polymorphisms and autism spectrum disorders in the Korean trios
• Association study of polymorphisms in N-methyl-D-aspartate receptor 2B subunits (GRIN2B) gene with Korean alcoholism
• Functional Characterization of DEAD-Box RNA Helicases in Arabidopsis thaliana under Abiotic Stress Conditions
• Study of the Strain in InN Thin Films Using Synchrotron X-Ray Scattering
• Assessment of the skin irritation potential of quantum dot nanoparticles using a human skin equivalent model
• Inflammatory Myofibroblastic Tumor of the Kidney in a Child : Report of a Case
• Microarray-based Analysis of Anti-angiogenic Activity of Demethoxycurcumin on Human Umbilical Vein Endothelial Cells : Crucial Involvement of the Down-regulation of Matrix Metalloproteinase
• Gastroesophageal flap valve is associated with gastroesophageal and gastropharyngeal reflux
• A comparative study of Response Evaluation Criteria in Solid Tumors (RECIST) and Computer-Aided Volume Measurement(International Forum on Medical Imaging in Asia 2009 (IFMIA 2009))
• Effect of Scutellariae Radix Extract on the High Glucose-Induced Apoptosis in Cultured Vascular Endothelial Cells(Biopharmacy)
• IS-53 Evaluation of length, volume and gray-scale histogram of the cervix as predictors of successful induction(Group7 Perinatology1,International Session)
• A RELATION ON SUBTRACTION ALGEBRAS
• Biotin-Avidin Mediated Homogeneous Enzyme-Linked Binding Assays for Riboflavin and Riboflavin Binding Protein Using Alkaline Phosphatase as the Label
• Effect of Melatonin on Cadmium-Induced Hepatotoxicity in Male Sprague-Dawley Rats
• Sex Determination of Bovine Embryos by the Polymerase Chain Reaction Using Y-Specific Primers
• Synthesis and Optical Characterization of Polycyanurates with Pendent Second-Order Nonlinear Optical Chromophores
• Over-expression of c-raf-1 proto-oncogene in liver cirrhosis and hepatocellular carcinoma
• Two New Acylated Flavonol Glycosides from Vicia amurensis
• A New Polyoxygenated Triterpene and Two New Aeginetic Acid Quinovosides from the Roots of Rehmannia glutinosa
• Multiple mucosa-associated lymphoid tissue organs involving marginal zone B cell lymphoma : organ-specific relationships and the prognostic factors. Consortium for improving survival of lymphoma study
• New Electrodeless Light Source Intensified by Electron Cyclotron Resonance Heating
• Stage IV marginal zone B-cell lymphoma - prognostic factors and the role of rituximab : Consortium for Improving Survival of Lymphoma (CISL) study
• MKK6 increases the melanocyte dendricity through the regulation of Rho family GTPases
• Optimal Trajectory for the Atlantooccipital Transarticular Screw
• THE ESSENCE OF SUBTRACTION ALGEBRAS
• Alleviation of OVA-Induced Airway Inflammation by Flowers of Inula japonica in a Murine Model of Asthma
• Residual anterior chamber angle closure in narrow-angle eyes following laser peripheral iridotomy : anterior segment optical coherence tomography quantitative study
• Effects of Transcutaneous Electrical Nerve Stimulation (TENS) on Changes in Postural Balance and Muscle Contraction following Muscle Fatigue
• Soft X-ray Microscope Constructed with 130-nm Spatial Resolution Using a High Harmonic X-ray Source
• Early versus delayed laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage
• Phloroglucinol Exerts Protective Effects Against Oxidative Stress-Induced Cell Damage in SH-SY5Y Cells
• Effects of Rhythmic Auditory Stimulation (RAS) on Gait Ability and Symmetry after Stroke

もっと見る 閉じる

スポンサーリンク