Folimycin (concanamycin A) and Bafilomycin A_1, Inhibitors Specific for V-ATPase,Exert Similar but Distinct Effects on Intracellular Translocation and Processing of Glycoproteins
スポンサーリンク
概要
- 論文の詳細を見る
Both folimycin and bafilomycin A_1, specific inhibitors of V-ATPase, blocked cell surface expression of viral envelope glyco-proteins without affecting their synthesis, but secretion of invertase was insensitive to both inhibitors. Invertase secreted in the presence of folimycin or bafilomycin A_1 migrated faster than the control on electrophoresis. A significant difference was also detected among the two treatments, suggesting that the sites of their action are different.
- 社団法人日本農芸化学会の論文
- 1994-02-23
著者
-
Yamasaki M
Department Of Biotechnology The University Of Tokyo:(present Address)department Of Food Science And
-
Nagao Kenji
Department Of Hygiene Chemistry Faculty Of Pharmaceutical Sciences Science University Of Tokyo
-
Nagao K
Department Of Agricultural Chemistry The University Of Tokyo
-
YAMASAKI Makari
Department of Agricultural Chemistry, the University of Tokyo
-
Nagao K
School Of Medicine And Center For Aids Research Kumamoto University
-
TAKATSUKI Akira
Institute of Physical and Chemical Research(RIKEN)
-
Muroi M
Riken Inst. Physical And Chemical Res. Saitama Jpn
-
Muroi Makoto
Animal And Cellular Systems Laboratory Riken(the Institute Of Physical And Chemical Research)
-
Takatsuki A
Riken Inst. Physical And Chemical Res. Saitama Jpn
-
Takatsuki Akira
Animal And Cellular Systems Laboratory Riken(the Institute Of Physical And Chemical Research)
-
SHIRAGAMI Nobue
Animal and Cellular Systems Laboratory, The Institute of Physical and Chemical Research (RIKEN)
-
Muroi Makoto
Department of Agricultural Chemistry, The University of Tokyo
-
Takatsuki Akira
Animal And Cellualr Systems Laboratory The Institute Of Physical And Chemical Research (riken)
-
Yamasaki Makari
Advanced Research Institute For The Science And Humanities Nihon University
-
Yamasaki Makari
Department Of Agricultural Chemistry The University Of Tokyo
-
Nagao Kazuhiko
Faculty Of Pharmaceutical Sciences Kumamoto University
-
Takatsuki A
Animal And Cellular Systems Laboratory Riken(the Institute Of Physical And Chemical Research)
-
Shiragami Nobue
Animal And Cellular Systems Laboratory The Institute Of Physical And Chemical Research (riken)
-
Nagao Kenji
Department Of Agricultural Chemistry The University Of Tokyo
関連論文
- Dietary Soy Protein Isolate and Its Undigested High Molecular Fraction Upregulate Hepatic ATP-Binding Cassette Transporter G5 and ATP-Binding Cassette Transporter G8 mRNA and Increase Biliary Secretion of Cholesterol in Rats
- S19159, a Modulator of Neurite Outgrowth Produced by the Ascomycete Preussia aemulans II. Structure Elucidation
- Selective Induction of Interleukin-1 Production and Tumor Killing Activity of Macrophages Through Apoptosis by the Inhibition of Oxidative Respiration
- Suppression of T Cell Stimulating Function of Allogeneic Antigen Presenting Cells by Prodigiosin 25-C
- Immunosuppressive Activity of Streptonigrin in Vitro and in Vivo
- Prodigiosin 25-C Perturbs Permeation of Acetate in a Cultured Cell Line
- Presentation of Exogenous Antigen by Macrophages But Not by Spleen Cells Is Inhibited by Leupeptin and Antipain
- Development and Characterization of Macrophage Hybridomas Derived from Murine Peritoneal Exudate Cells
- Effects of Microbial Products on Glucose Consumption and Morphology of Macrophages
- Melastin, a Novel Product of Streptomyces That Selectively Inhibits Leukemia Cell Growth
- Morphological Changes and Reorganization of Actinfilaments in Human Myeloid Leukemia Cells Induced by a Novel Protein Phosphatase Inhibitor, Tautomycin
- Effects of L-156,602,a C5a Receptor Antagonist, on Mouse Experimental Models of Inflammation
- Preferential Suppression of Delayed-type Hypersensitivity by L-156,602,a C5a Receptor Antagonist
- A Novel in Vivo Screening Method for Immunomodulating Substances : Development of an Assay System
- Multidrug Resistance Phenotype Conferred by Overexpressing bfr2^+/pad1^+/sks1^+or pap1^+Genes and Mediated by bfr1^+Gene Product, a Structural and Functional Homologue of P-Glycoprotein in Schizosaccharomyces pombe
- Dietary Gallate Esters of Tea Catechins Reduce Deposition of Visceral Fat, Hepatic Triacylglycerol, and Activities of Hepatic Enzymes Related to Fatty Acid Synthesis in Rats
- Okadaic Acid Remarkably Suppresses Testosterone Production in Murine Leydig Cells
- The Effects of Diesel Exhaust Particles (DEPs) on a Murine Testis (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
- Nordihydroguaiaretic Acid, of a New Family of Microtubule-stabilizing Agents, Shows Effects Differentiated from Paclitaxel(Biochemistry & Molecular Biology)
- Characterization of Glofibrate-induced Retrograde Golgi Membrane Movement to the Endoplasmic Reticulum : Clofibrate Distinguishes the Golgi from the Trans Golgi Network(Biochemistry & Molecular Biology)
- Glucosylceramide Synthesis Inhibitors Block Pharmacologically Induced Dispersal of the Golgi and Anterograde Membrane Flow from the Endoplasmic Reticulum : Implication of Sphingolipid Metabolism in Maintenance of the Golgi Architecture and Anterograde Mem
- Characterization of a Novel Fungal Protein, p15, Which Induces Neuronal Differentiation of PC12 Cells
- S19159, a Modulator of Neurite Outgrowth Produced by the Ascomycete Preussia aemulans I. Producing Strain, Fermentation, Isolation and Biological Activity
- Identification and Characterization of Porcine NP-190, a Novel Protein That Is Specifically Expressed in the Axonal Membrane during the Embryonic Period^1
- Isolation and Characterization of a 230 kDa Protein(p230) Specifically Expressed in Fetal Brains: Its Involvement in Neurite Outgrowth from Rat Cerebral Cortex Neurons Grown on Monolayer of Astrocytes
- Hop-Resistant Lactobacillus brevis Contains a Novel Plasmid Harboring a Multidrug Resistance-Like Gene
- TmrB Protein, Which Confers Resistance to Tunicamycin on Bacillus subtilis, Binds Tunicamycin
- The Gene Responsible for Tunicamycin Resistance, tmrB, in Bacillus subtilis(Microbilolgy & Fermentation Industry)
- Effects of Mepanipyrim on Intracellular Trafficking: A Comparative Study on Its Effects on Exocytic and Endocytic Trafficking of Proteins, Sphingolipids, and Cholesterol
- Folimycin (concanamycin A) and Bafilomycin A_1, Inhibitors Specific for V-ATPase,Exert Similar but Distinct Effects on Intracellular Translocation and Processing of Glycoproteins
- Folimycin (Concanamycin A), a Specific Inhibitor of V-ATPase, Blocks Intra-cellular Translocation of the Glycoprotein of Vesicular Stomatitis Virus before Arrival to the Golgi Apparatus
- Gene Amplification of the amy E-tmrB Region in Bacillus subtilis
- Brefeldin A, a Specific Inhibitor of Intracellular Translocation of Vesicular Stomatitis Virus G Protein: Intracellular Accumulation of High-mannose Type G Protein and Inhibition of Its Cell Surface Expression
- Stereochemical Configuration of 1-1 Glycosidic Linkages in Tunicamycin
- Effect of Brefeldin A on Biosynthesis of Cellular Components in Candida albicans
- A New Screening Procedure on Selective Inhibitors against SV40-Transformed Cells
- F13459, a New Derivative of Mycophenolic Acid : II. Physico-chemical Properties and Structural Elucidation
- F13459, a New Derivative of Mycophenolic Acid : I. Taxonomy, Isolation, and Biological Properties
- Fattiviracin A1, a Novel Antiviral Agent Produced by Streptomyces microflavus Strain No. 2445 II. Biological Properties
- The 9cis, 11trans, 13cis Isomer of Conjugated Linolenic Acid Reduces Apolipoprotein B100 Secretion and Triacylglycerol Synthesis in HepG2 Cells
- S-Propyl-Cysteine Sulfoxide and DL-Methionine Sulfoxide Inhibit the Secretion of Apolipoprotein B100 and Lipids in HepG2 Cells
- Comparison between Dietary Soybean Protein and Casein of the Inhibiting Effect on Atherogenesis in the Thoracic Aorta of Hypercholesterolemic (ExHC) Rats Treated with Experimental Hypervitamin D
- Induction of Two Types of Gene Amplification by a Cloned DNA Fragment and Amplification of a Foreign Gene on the Bacillus subtilis Chromosome by Using the Fragment
- Amplification of an Integration Plasmid Introduced into the tmr A Amplification Unit of A Bacillus subtitis Tunicamycin-resistant Mutant
- Construction of New ARSI Vectors with Increased Mitotic Stability in Saccharomyces cerevisiae(Microbiology & Fermentation Industry)
- Mutational Site in Tunicamycin-resistant Mutation tmrB8 of Bacillus subtilis as Revealed at the Nucleotide Sequence Level(Microbiology & Fermentation Industry)
- Efficacies of Different Secretion Vectors for Secretion of Human Epidermal Growth Factor by Escherichia coli(Biological Chemistry)
- Substrate Specificity of Acid Proteinase A from Aspergillus niger var. macrosporus
- Novel Saccharomyces cerevisiae Temperature-sensitive cyrl Mutant Which Accumulates Glycogen Particles
- recE-Dependent Gene Amplification Induced by a Tunicamycin-resistant Mutation (tmrA7) in Bacillus subtilis(Microbiology & Fermentation Industry)
- Expression and Secretion of Human Epidermal Growth Factor in Escherichia coli(Microbiology & Fermentation Industry)
- Sequence of the Signal Peptide of E. coli Alkaline Phosphatase
- Application of the Random Arbitrary Primed Polymerase Chain Reaction Differential Display Method to Isolate Genes of Cholesterol Metabolism-related Proteins from Rat Liver
- Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 II. Physico-chemical Properties and Structure Elucidation
- Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520 I. Taxonomy, Fermentation, Isolation and Biological Activities
- Conjugated Fatty Acids in Food and Their Health Benefits
- Novel Blockade of Call Surface Expression of Virus Glycoproteins by Leucinostatin A
- In Vivo Biotinylation of Fusion Proteins Expressed in Escherichia coli with a Sequence of Propionibacterium freudenreichii Transcarboxylase 1.3S Biotin Subunit
- Molecular Cloning of a Gene, DHS1, Which Complements a Drug-hypersensitive Mutation of the Yeast Saccharomyces cerevisiae
- Co-existing Proteins Interfere with the Action of Nordihydroguaiaretic Acid on Retrograde Golgi-to-ER Protein Trafficking in NRK Cells and α-Glucosidase Reaction in vitro
- Processing Glucosidase Inhibition by 1-Azafagomine
- Feeding Unsaponifiable Compounds from Rice Bran Oil Does Not Alter Hepatic mRNA Abundance for Cholesterol Metabolism-related Proteins in Hypercholesterolemic Rats
- Superiority of Dietary Safflower Oil over Olive Oil in Lowering Serum Cholesterol and Increasing Hepatic mRNAs for the LDL Receptor and Cholesterol 7α-Hydroxylase in Exogenously Hypercholesterolemic (ExHC) Rats
- Isomer-Specific Anti-Obese and Hypolipidemic Properties of Conjugated Linoleic Acid in Obese OLETF Rats
- Short-Term Feeding of Conjugated Linoleic Acid Does Not Induce Hepatic Steatosis in C57BL/6J Mice
- Alleviation of Fatty Liver by α-Linolenic Acid
- Purification of Conjugated Linoleic Acid Isomers through a Process Including Lipase-catalyzed Selective Esterification(Biochemistry & Molecular Biology)
- Conjugated Linoleic Acid Reduces Hepatic Microsomal Triacylglycerol Transfer Protein Activity and Hepatic Triacylglycerol Mass in Obese Rats
- Comparison of the Effects of Triacylglycerol-CLA and Free Fatty Acid-CLA on Hepatic Lipid Metabolism in OLETF Obese Rats
- Antiviral Activity of Fattiviracin FV-8 against Human Immunodeficiency Virus Type 1 (HIV-1)
- Reduced Expression of Perchloric Acid-Soluble Protein after Partial Hepatectomy in Rats
- Conjugated Linoleic Acid Reduces Body Fats and Cytokine Levels of Mice(Food & Nutrition Science)
- Dietary Manipulations of Body Fat-reducing Potential of Conjugated Linoleic Acid in Rats(Food & Nutrition Science)
- Defect in Cell Wall Integrity of the Yeast Saccharomyces cerevisiae Caused by a Mutation of the GDP-mannose Pyrophosphorylase Gene VIG9
- Molecular Characterization of a Novel Yeast Cell-wall Acid Phosphatase Cloned from Kluyveromyces marxianus
- Distinct Interaction of TmrB Protein with Membranes in Bacillus subtilis and Escherichia coli
- Cloning Genomic DNA Encoding Apple Polyphenol Oxidase and Comparison of the Gene Product in Escherichia coli and in Apple
- Purification and Characterization of Recombinant Human Granulocyte Colony-Stimulating Factor (rhG-CSF) Derivatives : KW-2228 and Other Derivatives
- Effects of Nonthermal Processes on the Inactivation of Microorganisms and Antioxidants in Minimally Processed Vegetables
- Biofilm formation by Escherichia coli in hypertonic sucrose media(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- High-Hydrostatic-Pressure Treatment Impairs Actin Cables and Budding in Saccharomyces cerevisiae (MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- High Hydrostatic Pressure Treatment Impairs AcrAB-TolC Pump Resulting in Differential Loss of Deoxycholate Tolerance in Escherichia coli(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Estimation of the Biofilm Formation of Escherichia coli K-12 by the Cell Number(Environmental Biotechnology)
- High Pressure Carbon Dioxide Decreases the Heat Tolerance of the Bacterial Spores
- Fosmidomycin Resistance in Adenylate Cyclase Deficient (cya) Mutants of Escherichia coli(Microbiology & Fermentation Technology)
- Effect of High Pressure Gaseous and Supercritical Carbon Dioxide Treatments on Bacterial Spores
- KJ1 Development of Neu-up, a Human G-CSF Derivative with Higher Specific Activity
- Inhibition of Protein Translocation in Permeabilized Cells of Schizosaccharomyces pombe by Puromycin
- Mixed-Species Biofilm Formation by Direct Cell-Cell Contact between Brewing Yeasts and Lactic Acid Bacteria
- Cytoplasmic Acidification May Occur in High-Pressure Carbon Dioxide-Treated Escherichia coli K12
- Physiological Effects of Dietary PIPS Soybean-Derived Phospholipid in Obese Zucker (fa-fa) Rats
- The Sulfated Polysaccharide Porphyran Reduces Apolipoprotein B100 Secretion and Lipid Synthesis in HepG2 Cells
- Effect of Vaccinium ashei reade Leaves on Lipid Metabolism in Otsuka Long-Evans Tokushima Fatty Rats
- Cell-Cycle Independent Chromosome Condensation in Schizosaccharomyces pombe Induced by High Hydrostatic Pressure Treatment
- Cessation of Cytokinesis in Schizosaccharomyces pombe during Growth after Release from High Hydrostatic Pressure Treatment
- STUDIES ON INFARCT SIZE AFTER THROMBOLYSIS IN ACUTE MYOCARDIAL INFARCTION. : INFARCT SIZE DETERMINED BY TTC METHOD : Myocardial Infarction : PROCEEDINGS OF THE 44th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Improved Production and Recovery of Alkaline Elastase from Alkalophilic Bacillus Strain by a Change of Medium Composition
- Effect of a Liver X Receptor Agonist on Deposition and Lymphatic Absorption of Plant Sterols in Stroke-Prone Spontaneously Hypertensive Rats Having a Mutation in ATP-Binding Cassette Transporter G5
- Effect of Vaccinium ashei reade Leaf Extracts on Lipid Metabolism in Obese OLETF Rats
- Effects of Lotus Root (the Edible Rhizome of Nelumbo nucifera) on the Deveolopment of Non-Alcoholic Fatty Liver Disease in Obese Diabetic db/db Mice