Dietary Soy Protein Isolate and Its Undigested High Molecular Fraction Upregulate Hepatic ATP-Binding Cassette Transporter G5 and ATP-Binding Cassette Transporter G8 mRNA and Increase Biliary Secretion of Cholesterol in Rats
スポンサーリンク
概要
- 論文の詳細を見る
Dietary soy protein isolate (SPI) and its undigested high molecular fraction (HMF) exhaustively digested with proteases, compared with casein (CAS), significantly reduced serum and liver cholesterol concentration in rats. Biliary excretion of cholesterol was significantly higher in rats fed SPI and HMF than in those fed CAS. Hepatic expression of ATP-binding cassette transporter G5 (ABCG5) and ATP-binding cassette transporter G8 (ABCG8) mRNA was significantly higher in rats fed SPI and HMF than in those fed CAS. These observations suggest that increased biliary excretion of cholesterol in SPI and HMF groups is caused by the enhanced expression of Abcg5/Abcg8.
- 2009-06-01
著者
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IKEDA Ikuo
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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KUDO Mariko
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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HAMADA Tadateru
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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NAGAO Koji
Laboratory of Nutrition Biochemistry, Faculty of Agriculture, Saga University
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OSHIRO Yoko
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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KATO Masaki
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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SUGAWARA Takashi
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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YAMAHIRA Takashi
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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ITO Hiroko
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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TAMARU Shogo
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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SATO Masao
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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IMAIZUMI Katsumi
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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NAGAOKA Satoshi
Laboratory of Molecular Function of Food, Faculty of Applied Biological Sciences, Gifu University
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YANAGITA Teruyoshi
Laboratory of Nutrition Biochemistry, Faculty of Agriculture, Saga University
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Yanagita Teruyoshi
佐賀大学 食糧科学
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Yanagita Teruyoshi
Laboratory Of Nutrition Biochemistry Faculty Of Agriculture Saga University
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Hamada Tadateru
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Hamada Tadateru
九州大学
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Hamada Tadateru
東北大学 農学研究科生体分子機能学
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Hamada Tadateru
九州大学 農学部栄養化学
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Hamada Tadateru
Laboratory Of Nutrition Chemistry Division Of Bioresource And Bioenvironmental Sciences Faculty Of A
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Ikeda Ikuo
九州大学
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Nagao K
School Of Medicine And Center For Aids Research Kumamoto University
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Sugano M
Faculty Of Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Sugano M
Faculty Of Environmental And Symbiotic Science Prefectural University Of Kumamoto
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Sugano Michihiro
Kumamoto Prefecture University
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Kyushu University
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Imaizumi Katsumi
Lab. Of Nutrition Chemistry Div. Of Bioresource And Bioenvironmental Sciences Graduate School Kyushu
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Imaizumi Katsumi
Lab. Of Nutrition Chemistry Fac. Of Agriculture Graduate School Of Kyushu Univ.
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Imaizumi K
Kyushu Univ. Fukuoka Jpn
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Faculty Of Bioresources And Bioenvironmental Sciences Graduate Sch
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Ikeda Ikuo
Graduate School Of Agricultural Sci. Tohoku Univ.
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Ki Masami
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Ki Masami
九州大学 農
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Sakono M
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Ikeda Ichiro
Department Of Food Science And Technology Faculty Of Agriculture Kyushu University
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Sato M
Laboratory Of Nutrition Chemistry Faculty Of Bioresources And Bioenvironmental Sciences Graduate Sch
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SUGANO Michihiro
Prefectural University of Kumamoto
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Sugano M
Kumamoto Prefectural Univ. Kumamoto Jpn
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Sugano Michihiro
Faculty Of Environmental And Symbiotic Science Prefectural University Of Kumamoto
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Sugano Michihiro
Fac. Of Environmental And Symbiotic Sciences Prefectural Univ. Of Kumamoto
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Sugano Michihiro
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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Sakono Masanobu
Department Of Biological Resource Sciences Faculty Of Agriculture Miyazaki University
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Nagao Koji
Laboratory Of Nutrition Biochemistry Faculty Of Agriculture Saga University
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Nagao Koji
Department Of Applied Biological Sciences Saga University
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Nagao Koji
Laboratory Of Nutrition Biochemistry Department Of Applied Biological Sciences Saga University
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Ikeda Ikuo
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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Ikeda Ikuo
Division Of Applied Biological Chemistry Department Of Bioscience And Biotechnology Faculty Of Agric
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Ikeda Ikuo
Department Of Bioscience And Biotechnology Division Of Bioresource And Bioenvironmental Sciences Gra
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Nagaoka Satoshi
Laboratory Of Molecular Function Of Food Faculty Of Applied Biological Sciences Gifu University
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Nagao Kazuhiko
Faculty Of Pharmaceutical Sciences Kumamoto University
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Yanagita Teruyoshi
Dep. Of Applied Biochemistry And Food Sci. Saga Univ.
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Yanagita Teruyoshi
Laboratory Of Nutrition Biochemistry Department Of Applied Biological Sciences Saga University
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Yanagita Teruyoshi
Wakamoto Pharmaceutical Co.
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Yanagita Teruyoshi
Faculty Of Agriculture Saga University
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Department Of Bioscience And Biotechnology Faculty Of Agriculture
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Department Of Food Science And Technology School Of Agriculture (4
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Sugano M
Laboratory Of Food Chemistry Division Of Bioresource And Bioenvironmental Sciences Graduate School K
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Ikeda Ikuo
東北大学 農学研究科生体分子機能学
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Oshiro Yoko
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Kudo Mariko
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Tamaru Shogo
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Iwamoto Hisao
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Sakono Masanobu
Dep. Of Biochemistry And Applied Biosciences Fac. Of Agriculture Univ. Of Miyazaki
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Iwamoto H
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Ikeda Ikuo
Laboratory Of Food And Biomolecular Science Department Of Food Function And Health Graduate School O
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Imaizumi K
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Kato Masaki
Laboratory For Biolinguistics Riken Brain Science Institute
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Sato Masao
Laboratory Of Nutrition Chemistry Division Of Bioresource And Bioenvironmental Sciences Graduate Sch
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Ikeda Ikuo
Laboratory Of Food And Biomolecular Science Department Of Food Function And Health Division Of Biosc
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Yanagita Teruyoshi
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Sugawara Takashi
Laboratory For Neurogenetics Riken Brain Science Institute
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Sugawara Takashi
Laboratory Of Food And Biomolecular Science Graduate School Of Agricultural Science Tohoku Universit
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Sato Masao
Laboratory Of Nutrition Chemistry Department Of Bioscience And Biotechnology Faculty Of Agriculture
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Kobayashi Makoto
Laboratory Of Nutrition Chemistry Department Of Bioscience And Biotechnology Faculty Of Agriculture
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Kudo Mariko
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University
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Imaizumi Katsumi
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School, Kyushu University
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Ikeda Ikuo
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University
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