Effects of Dietary Carbohydrates on Cholesterol Metabolism in Rats of Different Ages(Food & Nutrition)
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概要
- 論文の詳細を見る
Male Sprague-Dawley rats aged 1 month (young) and 9 months (adult) were fed diets containing sucrose, glucose or corn starch as a carbohydrate source for 4 weeks. Dietary sucrose increased (a) the liver size in rats of both ages, (b) the serum cholesterol level in adult rats, (c) the serum triglyceride level, especially in young rats, and (d) the liver cholesterol and triglyceride levels in adult rats. Consequently, there were age-related increases in serum and liver cholesterol in rats fed sucrose. No significant difference was found in the activity of liver 3-hydroxy-3-methylglutaryl coenzyme A reductase due to the diets in age-matched rats, whereas an age-related decrease was observed in rats fed simple sugars. Rats fed sucrose, especially adult rats, excreted more fecal steroids than ones fed glucose or corn starch. Sucrose tended to enhance the metabolism of linoleate to arachidonate, as judged from the fatty acid composition of liver microsomal phosphatidylcholine. Thus, sucrose exerts a peculiar effect on cholesterol metabolism in relation to age.
- 社団法人日本農芸化学会の論文
- 1989-05-23
著者
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IKEDA Ikuo
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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SUGANO Michihiro
Laboratory of Food Chemistry, Department of Food Science and Technology, Faculty of Agriculture (46-
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Ikeda Ikuo
Graduate School Of Agricultural Sci. Tohoku Univ.
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Sugano Michihiro
Faculty Of Environmental And Symbiotic Science Prefectural University Of Kumamoto
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Sugano Michihiro
Laboratory Of Food Chemistry Division Of Bioresource And Bioenvironmental Sciences Graduate School K
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Ikeda Ikuo
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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Ikeda Ikuo
Division Of Applied Biological Chemistry Department Of Bioscience And Biotechnology Faculty Of Agric
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Choi Yong
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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IMASATO Youji
Laboratory of Nutrition Chemistry, Kyushu University School of Agriculture
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Ikeda Ikuo
Laboratory Of Food And Biomolecular Science Department Of Food Function And Health Graduate School O
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Imasato Youji
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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Ikeda Ikuo
Laboratory Of Food And Biomolecular Science Department Of Food Function And Health Division Of Biosc
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