Missense Mutation in Abcg5 in SHRSP Rats Does Not Accelerate Intestinal Absorption of Plant Sterols : Comparison with Wistar Rats
スポンサーリンク
概要
- 論文の詳細を見る
Stroke-prone spontaneously hypertensive rats (SHRSP) deposit plant sterols in their bodies and have a mutation in ATP binding cassette transporter G5 (Abcg5). Lymphatic recovery rates of campesterol and sitosterol in SHRSP rats were comparable to those in Wistar rats, a strain that does not deposit plant sterols in the body and has no mutation in Abcg5. Higher absorption of stigmasterol and sitostanol was observed in SHRSP rats than in Wistar rats, but the differences between SHRSP and Wistar rats were quite small, because the absorbed amounts of these two sterols were much lower than those of campesterol and sitosterol. The in situ uptake of 3H-sitosterol and 14C-cholesterol solubilized in the bile salt micelle into intestinal mucosa was comparable between SHRSP and Wistar rats. These observations suggest that a mutation in Abcg5 does not greatly influence intestinal absorption of plant sterols in SHRSP rats, at least in comparison with Wistar rats.
- 社団法人 日本農芸化学会の論文
- 2009-02-23
著者
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IKEDA Ikuo
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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HAMADA Tadateru
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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IMAIZUMI Katsumi
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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Yanagita Teruyoshi
佐賀大学 食糧科学
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Yanagita Teruyoshi
Laboratory Of Nutrition Biochemistry Faculty Of Agriculture Saga University
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Hamada Tadateru
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Hamada Tadateru
九州大学
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Hamada Tadateru
東北大学 農学研究科生体分子機能学
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Hamada Tadateru
九州大学 農学部栄養化学
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Hamada Tadateru
Laboratory Of Nutrition Chemistry Division Of Bioresource And Bioenvironmental Sciences Faculty Of A
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Ikeda Ikuo
九州大学
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Yamada Koji
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Kyushu University
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Imaizumi Katsumi
Lab. Of Nutrition Chemistry Div. Of Bioresource And Bioenvironmental Sciences Graduate School Kyushu
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Imaizumi Katsumi
Lab. Of Nutrition Chemistry Fac. Of Agriculture Graduate School Of Kyushu Univ.
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Imaizumi K
Kyushu Univ. Fukuoka Jpn
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Faculty Of Bioresources And Bioenvironmental Sciences Graduate Sch
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GOTO Hitomi
Laboratory of Nutrition Chemistry, Department of Bioscience and Biotechnology, Faculty of Agricultur
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Ikeda Ikuo
Graduate School Of Agricultural Sci. Tohoku Univ.
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Goto Hitomi
九州大学 農学研究科栄養化学分野
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Kodama Yoko
Laboratory of Nutrition Chemistry, Department of Bioscience and Biotechnology, Faculty of Agricultur
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YOSHIDA Takeshi
Laboratory of Nutrition Chemistry, Department of Bioscience and Biotechnology, Faculty of Agricultur
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Ikeda Ikuo
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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Ikeda Ikuo
Division Of Applied Biological Chemistry Department Of Bioscience And Biotechnology Faculty Of Agric
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Ikeda Ikuo
Department Of Bioscience And Biotechnology Division Of Bioresource And Bioenvironmental Sciences Gra
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Yanagita Teruyoshi
Dep. Of Applied Biochemistry And Food Sci. Saga Univ.
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Yanagita Teruyoshi
Wakamoto Pharmaceutical Co.
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Yanagita Teruyoshi
Faculty Of Agriculture Saga University
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Department Of Bioscience And Biotechnology Faculty Of Agriculture
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Imaizumi Katsumi
Laboratory Of Nutrition Chemistry Kyushu University School Of Agriculture
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Yasumoto K
Second Department Of Surgery School Of Medicine University Of Occupational And Environmental Health
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Ikeda Ikuo
東北大学 農学研究科生体分子機能学
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Goto Hitomi
Laboratory Of Functional Food Science And Coe Program In The 21st Century School Of Food And Nutriti
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Ikeda Ikuo
Laboratory Of Food And Biomolecular Science Department Of Food Function And Health Graduate School O
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Yamada K
Lab. Of Nutrition Chemistry Dep. Of Bioscience And Biotechnology Fac. Of Agriculture Graduate School
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Imaizumi K
Laboratory Of Nutrition Chemistry Faculty Of Agriculture Graduate School Of Kyushu University
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Ikeda Ikuo
Laboratory Of Food And Biomolecular Science Department Of Food Function And Health Division Of Biosc
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Yoshida Takeshi
Laboratory Of Biochemistry Department Of Bioscience And Biotechnology Faculty Of Agriculture Graduat
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Imaizumi Katsumi
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School, Kyushu University
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Ikeda Ikuo
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University
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Yoshida Takeshi
Laboratory of Bio-Functional Molecular Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University
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