Effect of Dietary Conjugated Linoleic Acid on Liver Regeneration after a Partial Hepatectomy in Rats
スポンサーリンク
概要
- 論文の詳細を見る
We examined the effect of dietary conjugated linoleic acid (CLA) on liver regeneration after a partial hepatectomy (PH) in Sprague-Dawley rats. PH was performed on rats fed a 0 or 1 wt.% CLA diet for 3 wk. Average liver weight in the CLA fed rat population was heavier than the control rat population at the time of PH and 1-d after PH. Conversely, CLA fed rats' liver weight was significantly lower than control rats at 7-d after PH. This suggests that dietary CLA reduced liver weight gain after PH. Dietary CLA did not affect serum aspartate aminotransferase (AST) or alanine aminotransferase (ALT) activities. However, CLA significantly reduced serum albumin levels at 1-d but not at 7-d after PH. 5-Bromo- and 5-iododeoxyuridine incorporation into hepatocytes 1-d post PH was lower in the CLA group. In conclusion, the data suggests that dietary CLA inhibits DNA synthesis after PH, which results in hepatocyte proliferation inhibition.
- 日本ビタミン学会の論文
著者
-
安田 伸
東海大学農学部バイオサイエンス学科
-
安田 伸
九州大学大学院農学研究院生物機能科学部門生物機能化学講座食糧化学教室
-
MAEHARA YOSHIHIKO
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
-
Hirao Akira
Polymeric And Organic Materials Department Graduate School Of Science And Engineering Tokyo Institut
-
Hirao Akira
九州大学 農学部
-
Hirao Akira
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Hirao A
Tokyo Inst. Technol. Tokyo Jpn
-
Yamashita Masahiro
Department Of Bioengineering Tokyo Institute Of Technology
-
SHIMADA Mitsuo
Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, University of Tokush
-
Maehara Yoshihiko
Department Of Surgery And Science Graduate School Of Medical Sciences Kyushu University
-
Yamada Koji
Department Of Bioscience And Biotechnology Faculty Of Agriculture Kyushu University
-
TSUJITA EIJI
Department of Surgery, Graduate School of Medical Sciences, Kyushu University
-
YAMADA Koji
Laboratory of Food Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Ky
-
TACHIBANA Hirofumi
Laboratory of Food Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Ky
-
Tachibana H
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Tachibana Hirofumi
九州大学 農学部生物機能化学食糧化学
-
Tachibana Hirofumi
Graduate School Of Genetic Resources Technology Kyushu University
-
Yamada Koji
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Yasuda Shin
Tokai Univ. Kumamoto Jpn
-
Yazawa K
九州大学 農学部生物機能化学食糧化学
-
Shimada Mitsuo
Department Of Digestive And Pediatric Surgery Institute Of Health Biosciences University Of Tokushim
-
Hirao Akira
Department Of Agronomy Faculty Of Agriculture Tottori University
-
YAMASAKI Masao
Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of Bioscience and
-
CHUJO Hitomi
Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of Bioscience and
-
KOYANAGI Nami
Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of Bioscience and
-
KANOUCHI Hiroaki
Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of Bioscience and
-
YASUDA Shin
Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of Bioscience and
-
MATSUO Aya
Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of Bioscience and
-
NISHIDA Eri
Laboratory of Food Chemistry, Division of Applied Biological Chemistry, Department of Bioscience and
-
RIKIMARU Tatsuya
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
-
Yasuda Shin
School Of Agriculture Tokai University
-
Maehara Yoshihiko
Department Of Surgery And Medical Science Graduate School Of Medical Sciences Kyushu University
-
Miyazaki Yoshiyuki
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Tachibana Hirofumi
Department Of Food Science And Technology Faculty Of Agriculture Kyushu University
-
Tachibana Hirofumi
Laboratopy Of Food Chemistry Department Of Bioscience And Biotechnology Division Of Bioresource And
-
Yasuda Shin
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Yasumoto K
Second Department Of Surgery School Of Medicine University Of Occupational And Environmental Health
-
Yamada K
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Matsuo Aya
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Nishida Eri
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Chujo Hitomi
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Tsujita Eiji
Department Of Surgery And Science Graduate School Of Medical Sciences Kyushu University
-
Koyanagi Nami
Laboratory Of Food Chemistry Division Of Applied Biological Chemistry Department Of Bioscience And B
-
Rikimaru T
Department Of Surgery And Science Graduate School Of Medical Sciences Kyushu University
-
Yamasaki Masao
Department Of Biochemistry And Applied Biosciences Faculty Of Agriculture University Of Miyazaki
-
Miyazaki Y
Dep. Of Life Sci. Graduate School Of Bioscience And Biotechnology Tokyo Inst. Of Technol.
-
Yamasaki Masao
Department Of Biochemistry And Applied Biosciences Faculty Of Agriculture Miyazaki University
-
Kanouchi Hiroaki
Kagoshima Univ. Kagoshima
-
Tian Huaize
Department Of Bioscience And Biotechnology Faculty Of Agriculture Kyushu University
-
Maehara Yoshihiko
Department Of Biochemistry Kawasaki Medical School
-
Yamada Koji
Laboratopy Of Food Chemistry Department Of Bioscience And Biotechnology Division Of Bioresource And
-
Rikimaru Tatsuya
Department Of Surgery And Science Graduate School Of Medical Sciences Kyushu University
-
TACHIBANA Hirofumi
Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University
-
安田 伸
東海大・農・バイオ
-
MAEHARA Yoshihiko
Deparment of Surgery and Science, Graduate School of Medical Science, Kyushu University
関連論文
- Inhibitory Effects of Nitrative Stress on the Sulfation of 17β-Estradiol and 4-Methoxyestradiol by Human MCF 10A Mammary Epithelial Cells
- バイオ「チーズ」の味わい(バイオミディア)
- 大豆中の機能性因子の利用効率に及ぼす大豆粉末粒径の影響
- Sprague-Dawleyラットの脂質代謝,免疫機能に及ぼすイチョウ葉および竹エキス粉末の摂食効果
- 疾病環境における硫酸転移酵素とそのはたらき
- サルベージ温熱化学療法が奏功した根治的化学放射線療法後再発食道癌の一例
- High expression of insulin-like growth factor binding protein-3 is correlated with lower portal invasion and better prognosis in human hepatocellular carcinoma
- Characteristic differences according to the cirrhotic pattern of advanced primary biliary cirrhosis : Macronodular cirrhosis indicates slow progression
- Proctocolectomy for Colon Cancer Associated with Ulcerative Colitis a Few Months After Living Donor Liver Transplantation for Primary Sclerosing Cholangitis : Report of a Case
- Liver Metastasis with Intraductal Invasion Originating from Rectal Cancer : Report of a Case
- Small-Intestinal Volvulus Around the Superior Mesenteric Artery as an Extremely Rare Positioning-Associated Complication After Percutaneous Liver Biopsy
- Characteristics of biliary reconstruction using a T-tube as compared with other methods in left-lobe adult living-donor liver transplantation
- Stenotrophomonas maltophilia Bacteremia After Living Donor Liver Transplantation : Report of a Case
- Living Donor Liver Transplantation in a Patient with Giant Hepatic Hemangioma Complicated by Kasabach-Merritt Syndrome : Report of a Case
- Liver transplantation for hepatocellular carcinoma
- A New Strategy for Lung Cancer Treatment : Impact of Real-Time Navigation on Thoracoscopic Surgery
- Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population
- Alcohol dehydrogenase and aldehyde dehydrogenase polymorphisms and colorectal cancer : The Fukuoka Colorectal Cancer Study
- Physical activity and colorectal cancer : The Fukuoka Colorectal Cancer Study
- Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer : The Fukuoka Colorectal Cancer Study
- Molecular Cloning, Expression and Characterization of A Novel Mouse SULT6 Cytosolic Sulfotransferase
- Genetic polymorphisms of cyclooxygenase-2 and colorectal adenoma risk : The Self Defense Forces Health Study
- Genetic analysis of expression profile involved in retinoid metabolism in non-alcoholic fatty liver disease
- 3P-1059 ニューロステロイド硫酸転移酵素の諸性質の検討(2a酵素学,酵素工学,一般講演,酵素学,タンパク質工学および酵素工学,伝統の技と先端科学技術の融合)
- バイオ「チーズ」の味わい
- Effect of Dietary Conjugated Linoleic Acid on Liver Regeneration after a Partial Hepatectomy in Rats
- Intrapartum placement of an inferior vena cava filter for a woman with hereditary antithrombin III deficiency : Its role in the prevention of fatal pulmonary embolism
- Intratumoral Expression of Macrophage Migration Inhibitory Factor is Correlated with Serum C-Reactive Protein and Interleukin-6 in Patients with Non-Small Cell Lung Cancer
- Oral Contraceptives as Substrates and Inhibitors for Human Cytosolic SULTs
- Synovial sarcoma of the chest wall
- Endotracheal Surgery for Leiomyoma of the Trachea
- The Dynamics and Clinical Significance of Alpha 2 Plasmin Inhibitor-Plasmin Complex and Thrombin-Antithrombin Complex in Postoperative Pleural Effusion Following a Pulmonary Lobectomy
- Schwannoma in the peridiaphragm
- Impact of Smoking Status on the Biological Behavior of Lung Cancer
- Peritoneal Dissemination of Early Gastric Cancer : Report of a Case
- A Novel Fermented Food Product Prepared from Soybean Protein-Calcium-Gel with Monascus Fungus : Changes in Protein and Nitrogen Compounds during Fermentation
- Effect of yacon silage on feed digestibility, blood characteristics and amount of urinary 8-hydroxydeoxyguanosine in ewes
- Genetic Alteration in Carcinoid Tumors of the Lung
- On the Sulfation and Methylation of Catecholestrogens in Human Mammary Epithelial Cells and Breast Cancer Cells(Miscellaneous)
- High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer
- Postoperative Management Using Intensive Patient-Controlled Epidural Analgesia and Early Rehabilitation After an Esophagectomy
- Colon Metastasis 20 Years After the Removal of Ovarian Cancer : Report of a Case
- Esophagectomy in patients 80 years of age and older with carcinoma of the thoracic esophagus
- p53 Gene mutations in esophageal squamous cell carcinoma and their relevance to etiology and pathogenesis : Results in Japan and comparisons with other countries
- Trastuzumab and breast cancer : developments and current status
- Activation of PI3K/Akt signaling and hormone resistance in breast cancer
- Tissue-specific Distribution of Genistein, Daidzein and Bisphenol A in Male Sprague-Dawley Rats after Intragastric Administration
- Current Status of Pulmonary Metastasectomy from Primary Epithelial Tumors
- Favorable Surgical Results for Patients with Nonsmall Cell Lung Cancer over 80 Years Old : A Multicenter Survey
- Intrapleural Hypotonic Cisplatin Treatment for Malignant Pleural Mesothelioma : In Vitro Experiments and Clinical Application
- Outcome of a Pulmonary Metastasectomy for an Orthopedic Malignancy
- Serum Tissue Inhibitors of Metalloproteinase-1 and -2 in Patients with Non-Small Cell Lung Cancer
- Leiomyosarcoma of the Greater Omentum with Liver Metastasis : Report of a Case
- Laparoscopic Repair of a Perforated Duodenal Ulcer in Two Patients
- Resection of Radiation-Induced Sarcoma of the Clavicle
- Extension of Liver Tissue into the Thorax Following a Right Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma
- Thoracoscopic Surgery Combined with a Supraclavicular Approach for Removing a Cervico-Mediastinal Neurogenic Tumor : A Case Report
- Expression profile of lipid metabolism-associated genes in hepatitis C virus-infected human liver
- Methodological aspects of current problems in target-based anticancer drug development
- DNA repair dysfunction in gastrointestinal tract cancers
- Current topics and the clinical effects of target-based antineoplastic agents
- Mock Circulatory Systems for Vascular Tissue Engineering
- Phase II Study of Weekly Paclitaxel by One-Hour Infusion for Advanced Gastric Cancer
- Association between Arterial Stiffness and Cerebral White Matter Lesions in Community-Dwelling Elderly Subjects
- Extracorporeal Shock Wave Therapy Improves Blood Flow in a Rabbit Model of Mild Hindlimb Ischemia(Peripheral Circulation/Vascular Disease 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Effect of liver transplantation on multiple bone fractures in an infant with end-stage biliary atresia : a case report
- The Specific Expression of Three Novel Splice Variant Forms of Human Metalloprotease-like Disintegrin-like Cysteine-rich Protein 2 Gene in Brain Tissues and Gliomas
- Granulocyte-Colony Stimulating Factor-Producing Gallbladder Cancer Without Recurrence More than 2 Years After Resection : Report of a Case
- Simultaneous Determination of Isoflavones and Bisphenol A in Rat Serum by High-performance Liquid Chromatography Coupled with Coulometric Array Detection
- Voltage Dependency in Coulometric Analysis of Tea Polyphenols and Isoflavones in Foodstuffs
- Treatment of Solitary Iliac Aneurysms : Clinical Review of 28 Cases
- Surgical Management of Abdominal Aortic Aneurysm Associated with Polycystic Kidney Disease : Report of Two Cases
- Primary Osteosarcoma of the Lung : A Case Report
- Lung Cancer with p53 Expression and a Solitary Metastasis to the Stomach : A Case Report
- A Phase II Trial of a New 5-Fluorouracil Derivative, BOF-A2 (Emitefur), for Patients with Advanced Gastric Cancer
- Prognostic value of thymidine phosphorylase activity in liver tissue adjacent to hepatocellular carcinoma
- Preoperative Mechanical Bowel Preparation Unnecessary in Patients Undergoing Thoracic Surgery
- Microsatellite Instability in Gastrointestinal Tract Cancers : A Brief Update
- Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus : epidemiology, clinical findings, and prevention
- Completely Wide Resection of Malignant Fibrous Histiocytoma of the Chest Wall ; Expect for Long Survival
- Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus : molecular mechanisms of carcinogenesis
- Surgical Outcome of an Anatomical Resection of Clinical Stage IA Non-Small Cell Lung Cancer Assisted with a Video-Thoracoscopy
- The Role of Serum Interleukin-8 in Hepatic Resections
- Acute Biliary Obstruction Due to a Large Intracholedochal Hematoma After Living-Donor Liver Transplantation : Report of a Case
- Impact of amino acid substitutions in the core region of HCV om multistep hepatocarcinogenesis
- Impact of Perioperative Peripheral Blood Values on Postoperative Complications After Esophageal Surgery
- Activation of Morphine Glucuronidation by Fatty Acyl-CoAs and Its Plasticity : A Comparative Study in Humans and Rodents Including Chimeric Mice Carrying Human Liver
- Superdrainage of the Ileocolic Vein to the Internal Jugular Vein Interposed by an Inferior Mesenteric Vein Graft in Replacing the Esophagus with the Right Hemicolon
- Strategies for Treating Liver Metastasis from Gastric Cancer
- Successful Treatment of Acute Esophageal Necrosis Caused by Intrathoracic Gastric Volvulus : Report of a Case
- An Assessment of Surgery for Portal Hypertensive Patients Performed at a Single Community Hospital
- Tumor-infiltrating lymphocytes and hepatocellular carcinoma : pathology and clinical management
- Curative Surgery Improves the Survival of Patients with Perforating Colorectal Cancer
- A Survey of the Effects of Sivelestat Sodium Administration on Patients with Postoperative Respiratory Dysfunction
- Laparoscopic Treatment of Splenosis : Report of a Case
- Effect of Thrombopoietin on Platelet Counts and Liver Regeneration After Partial Hepatectomy in a Rat Model
- Technical standardization of laparoscopic splenectomy harmonized with hand-assisted laparoscopic surgery for patients with liver cirrhosis and hypersplenism
- アントシアニン含有甘藷を活用した機能性成分の有効利用(飼料化)に関する研究
- 大豆残渣中に含まれる免疫調節因子の特定および体内デトックス代謝機能に及ぼす影響評価 (第14回研究報告会記録)
- 様々な牛乳由来チーズによるRAW264.7マウスマクロファージ細胞の一酸化窒素産生誘導