Missense Mutation of Abcg5 in Stroke-Prone Spontaneously Hypertensive Rats Does Not Influence Lymphatic Sitosterol Absorption Regardless of the Dose: Comparison with Wistar Rats
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概要
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The lymphatic recovery of radiolabeled sitosterol administered in various amounts to the stomach was almost the same between stroke-prone spontaneously hypertensive rats (SHRSPs), a strain having a missense mutation in ATP binding cassette transporter g5 (Abcg5), and Wistar rats, a normal strain. The results suggest that the mutation of Abcg5 in SHRSPs, compared with Wistar rats, did not influence the ability for intestinal sitosterol absorption regardless of the dose.
著者
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IKEDA Ikuo
Laboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku Univers
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HAMADA Tadateru
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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IMAIZUMI Katsumi
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Graduate School of Kyushu University
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Kodama Yoko
Laboratory of Nutrition Chemistry, Department of Bioscience and Biotechnology, Faculty of Agricultur
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