Activation Effects of Allium Tuberosum Rottl. on Choline Acetyltransferase
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概要
- 論文の詳細を見る
An ethanolic extract of Allium tuberosum Rottl. demonstrated potent choline acetytrasferase (ChAT) activating activity (45%) among 30 screened Korean edible plants. The ChAT activator of A. tuberoum Rottl. was purified and identified as ferulic acid [4-hydroxy-3-methoxycinnamic acid] via silica-gel open-column chromatography, HPLC, EI-MS, and 1H/13C-NMR. The ferulic acid from A. tuberoum Rottl. exhibited ChAT activity in a dose-dependent manner and showed notoxicity in a cell viability assay (MTT assay). We suggest that the ferulic acid from A. tuberoum Rottl. was the strong ChAT activator.
- 社団法人 日本農芸化学会の論文
著者
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KIM Hye
Department of Food and Nutrition, Chungnam National University
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KIM Chang-Ju
Department of Physiology, College of Medicine, Kyung Hee University
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Kim Hye
韓国
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Kim Young
Department Of Electronics Engineering Korea Advance Intitute Of Science & Technology
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Choi Soo
Graduate School Of Life Sciences And Biotechnology Korea Univ.
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Shin Dong-hoon
Department Of Preventive Medicine School Of Medicine & Institute For Medical Genetics Keimyung U
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KIM Mi
Graduate School of Life Sciences and Biotechnology, Korea University
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HONG Bumshik
Department of Food and Biotechnology, Korea University
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