Protective Effects of Kaempferol (3,4',5,7-tetrahydroxyflavone) against Amyloid Beta Peptide (Aβ)-Induced Neurotoxicity in ICR Mice
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概要
- 論文の詳細を見る
To determine the effects of kaempferol, rat pheochromocytoma cells (PC12) and Institute of Cancer Research (ICR) mice were utilized as neuronal models. Using in vitro assays, kaempferol was shown to have protective effects against oxidative stress-induced cytotoxicity in PC12 cells. Administration of kaempferol also significantly reversed amyloid beta peptide (Aβ)-induced impaired performance in a Y-maze test. Taken altogether, the results reported here suggest that further investigation is warranted of the influence of kaempferol on pathways related to Alzheimer’s disease.
- 社団法人 日本農芸化学会の論文
- 2010-02-23
著者
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KIM Hye
Department of Food and Nutrition, Chungnam National University
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Kim C‐j
Department Of Physiology College Of Medicine Kyung Hee University
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Kim C‐j
Kyung Hee Univ. Seoul Kor
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KIM Chang-Ju
Department of Physiology, College of Medicine, Kyung Hee University
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Kim Jae
Department of Anatomy, College of Medicine, Pusan National University
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Kim Chang-ju
韓国
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Kim Hye-kyung
Dep. Of Food And Biotechnology Hanseo Univ.
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Kim Hye
韓国
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Kim Young
Department Of Electronics Engineering Korea Advance Intitute Of Science & Technology
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Kim Young
Dep. Of Food And Biotechnology Korea Univ.
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Choi Soo
Graduate School Of Life Sciences And Biotechnology Korea Univ.
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Kim Young
Department Of Agricultural Chemistry The University Of Tokyo
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Shin Dong-hoon
韓国
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Shin D‐h
Millimeter-wave Innovation Technology Research Center (mint) Dongguk University
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Shin Dong‐hoon
Department Of Food And Biotechnology Korea University
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Shin Dong-hoon
Department Of Preventive Medicine School Of Medicine & Institute For Medical Genetics Keimyung U
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CHO Hong
Department of Food and Biotechnology, Korea University
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HWANG Han-Joon
Department of Food and Biotechnology, Korea University
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Cho Hong
Dep. Of Food And Biotechnology Korea Univ.
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Cho Hong-yon
Dep. Of Food Technol. Graduate School Of Life Sciences And Biotechnology Korea Univ.
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Kim Chang-ju
Department Of Physiology College Of Medicine Kyung Hee University
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Shin Dong-hoon
Department Of Food And Biotechnology Korea University
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Cho Hong
Graduate School Of Biotechnology Korea University
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Kim Chang-ju
Dep. Of Physiology Kyung Hee Univ.
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Kim Hyun-mi
Department Of Pharmaceutical Lab. Central Research Institute Ilyang Pharm Co.
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Kim Jae
Department Of Anatomy College Of Medicine Pusan National University
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Kim Hye
Department Of Anesthesiology And Pain Medicine Konkuk University Chungju-hospital
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LIM Seung
Graduate School of Life Sciences and Biotechnology, Korea University
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PETERSON Sabrina
Department of Food Science and Nutrition, University of Minnesota
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Lim Seung-taik
Graduate School Of Life Sciences And Biotechnology Korea University
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Lim Seung-taik
Department Of Food Technology School Of Life Sciences And Biotechnology Korea University
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Hwang Han-joon
Department Of Food And Biotechnology Korea University
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Cho Hong
Department Of Food And Biotechnology Korea University
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Peterson Sabrina
Department Of Food Science And Nutrition University Of Minnesota
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Kim Jae
Department Of Food And Biotechnology Korea University
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Kim Jae
Department Of Anatomy And Brain Korea 21 Project For Medical Science Yonsei University College Of Medicine
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Kim Hye
Department of Food and Biotechnology, Hanseo University
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SHIN Dong
Department of Food and Biotechnology, Korea University
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CHO Hong
Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine
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Kim Jae
Deparment of Obstetrics and Gynecology, Seoul National University Collge of Medicine
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