Protective Effects of Kaempferol (3,4′,5,7-tetrahydroxyflavone) against Amyloid Beta Peptide (Aβ)-Induced Neurotoxicity in ICR Mice
スポンサーリンク
概要
- 論文の詳細を見る
To determine the effects of kaempferol, rat pheochromocytoma cells (PC12) and Institute of Cancer Research (ICR) mice were utilized as neuronal models. Using in vitro assays, kaempferol was shown to have protective effects against oxidative stress-induced cytotoxicity in PC12 cells. Administration of kaempferol also significantly reversed amyloid beta peptide (Aβ)-induced impaired performance in a Y-maze test. Taken altogether, the results reported here suggest that further investigation is warranted of the influence of kaempferol on pathways related to Alzheimer’s disease.
- 社団法人 日本農芸化学会の論文
著者
-
KIM Hye
Department of Food and Nutrition, Chungnam National University
-
KIM Chang-Ju
Department of Physiology, College of Medicine, Kyung Hee University
-
Kim Jae
Department of Anatomy, College of Medicine, Pusan National University
-
Kim Young
Department Of Electronics Engineering Korea Advance Intitute Of Science & Technology
-
Choi Soo
Graduate School Of Life Sciences And Biotechnology Korea Univ.
-
Shin Dong-hoon
Department Of Preventive Medicine School Of Medicine & Institute For Medical Genetics Keimyung U
-
CHO Hong
Department of Food and Biotechnology, Korea University
-
HWANG Han-Joon
Department of Food and Biotechnology, Korea University
-
LIM Seung
Graduate School of Life Sciences and Biotechnology, Korea University
-
PETERSON Sabrina
Department of Food Science and Nutrition, University of Minnesota
関連論文
- Spirulina Prevents Atherosclerosis by Reducing Hypercholesterolemia in Rabbits Fed a High-Cholesterol Diet
- IS-12 Limited benefit of neoadjuvant chemotherapy before surgery in FIGO stage IB-IIA cervical cancer : a case-control study and meta-analysis(Group2 Oncology2,International Session)
- Maternal Alcohol Administration Suppresses Expression of Nitric Oxide Synthase in the Hippocampus of Offspring Rats
- Effects of Corydalis Tuber on synthesis of NO and PGE_2 in murine macrophage RAW 264.7 cells stimulated by LPS(International Conference on Mind Body Science : Physical and Physiological Approach joint with The Eighteenth Symposium on Life Information Scie
- Atractylodes japonica Suppresses Lipopolysaccharide-Stimulated Expressions of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 in RAW 264.7 Macrophages (Pharmacology)
- Protective Effect of Aqueous Extract of Ginseng radix against 1-Methyl-4-phenylpyridinium-Induced Apoptosis in PC12 Cells (Pharmacology)
- Red Ginseng Inhibits Exercise-Induced Increase in 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in Dorsal Raphe of Rats
- Folium mori Increases Cell Proliferation and Neuropeptide Y Expression in Dentate Gyrus of Streptozotocin-Induced Diabetic Rats
- Bee Venom Induces Apoptosis and Inhibits Expression of Cyclooxygenase-2 mRNA in Human Lung Cancer Cell Line NCI-H1299
- Effects of Paeonia radix on 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in the Dorsal Raphe of Exercised Rats
- Effect of Puerariae radix on c-Fos Expression in Hippocampus of Alcohol-Intoxicated Juvenile Rats(Pharmacology)
- A dministration of Folium mori Extract Decreases Nitric Oxide Synthase Expression in the Hypothalamus of Streptozotocin-Induced Diabetic Rats
- Effects of Puerariae radix on Cell Proliferation and Nitric Oxide Synthase Expression in Dentate Gyrus of Alcohol-Intoxicated Sprague-Dawley Rats
- Serotonin Induces Apoptosis in PGT-β Pineal Gland Tumor Cells
- Effects of Corydalis Tuber on synthesis of NO and PGE_2 in murine macrophage RAW 264.7 cells stimulated by LPS(International Conference on Mind Body Science : Physical and Physiological Approach joint with The Eighteenth Symposium on Life Information Scie
- Expression of Mucins in the Human Fetal and Neonatal Stomach
- P1-IS-48 Diabetes Mellitus Following Platinum-Based Chemotherapy in Patients with Gynecologic Malignancy
- P1-IS-38 The Safety and Efficacy of Belotecan in Patients with Recurrent or Refractory Ovarian Cancer
- P1-IS-6 The mRNA and protein expressions of cell division cycle 25 phosphatase in cervical carcinoma and their correlations with clinicopathologic factors
- Reparixin, an inhibitor of CXCR1 and CXCR2 receptor activation, attenuates blood pressure and hypertension-related mediators expression in spontaneously hypertensive rats
- P-IS-44 Correlation of HLA-G gene Expression with Various Prognostic Factors in Ovarian Carcinoma(Oncology 12,Group 99,International Session)
- P-IS-41 Analysis of Chromosomal Changes in Serous Ovarian Carcinoma by Microarray Comparative Genomic Hybridization : Potential Predictive Markers for Chemoresistant Disease(Oncology 11,Group 98,International Session)
- Immunohistochemical analysis of p16INK4A protein overexpression in cervical intraepithelial neoplasia(Oncology 4)
- 2-8.Clinical Usefulness of Cervicogram as Primary Screening Test of Cervical Intraepithelial Neoplasia(Session 3 Oncology 3)
- Optical Bistability in a Semiconductor Etalon with Nonlinear Integrated Mirrors
- A Novel Method of Boron Delivery Using Sodium Iodide Symporter for Boron Neutron Capture Therapy
- Novel Benzodioxan Derivative, 5-{3 - [((2S) - 1,4 - Benzodioxan - 2 - ylmethyl) amino]propoxy} - 1,3 - benzodioxole HCl (MKC - 242), with a Highly Potent and Selective Agonist Activity at Rat Central Serotonin_ Receptors
- Increased Expression of Hypothalamic NADPH-Diaphorase Neurons in Mice with Iron Supplement
- Suppressive Effect of Punica granatum on the Production of Tumor Necrosis Factor (Tnf) in BV2 Microglial Cells(Pharmacology)
- Two-Domain Hybrid-Aligned Nematic Cell Fabricated by Ion Beam Treatment of Vertical Alignment Layer
- Horizontal Switching of Half-Wave Liquid Crystal Cell for Transflective Display
- In-Plane-Switching Liquid Crystal Cell with Zigzag Electrodes for Tansflective Displays
- Simple Cell Gap Measurement Method for Twisted-Nematic Liquid Crystal Cells
- Optimization of Panel Parameters and Drive Signals for High-Speed Matrix Addressing of a Bistable Twisted-Nematic Liquid Crystal Display
- IS-13 Management of retroperitoneal lymph nodes in advanced ovarian cancer(Group2 Oncology1,International Session)
- IS-15 Adjuvant Concurrent Chemoradiotherapy-Induced Neutropenia as a Prognostic Indicator of Treatment in Cervical Cancer(Group2 Oncology1,International Session)
- IS-103 Analysis of Cervical Cancer Cases with Negative Results on Hybrid Capture II Tests(Group12 Oncology4,International Session)
- Disease confined within the ovary and smaller amount of ascites are good prognostic factors for survival of patients with squamous cell carcinoma arising from mature cystic teratoma of the ovary : A case series in Korea and review of the published reports
- P3-IS-1 Polymorphisms of ERCC1 C8092A and Glutathione-S-Transferase T1 (GSTT1) Associated With Survival and Response After Platinum Based Chemotherapy in Patients With Epithelial Ovarian Cancer(Group85 Oncology1,International Session)
- Matrix metalloproteinase-1 promoter polymorphism and epithelial ovarian cancer : Does ethnicity matter?
- P1-IS-10 Can preoperative MRI correctly evaluate nodal and parametrial invasion in early stage cervical cancer?
- P1-IS-4 Altered level of Smad4 is associated with human cervical carcinogenesis
- Nitric Oxide Induces Apoptosis in Mouse C2C12 Myoblast Cells
- Protective Effects of Puerariae flos Against Ethanol-Induced Apoptosis on Human Neuroblastoma Cell Line SK-N-MC
- Crystal Structure of N-tert-Butoxycarbonylbis(2-thioacetoxyethyl)amine
- The Suppressive Effect of β-Glucan on the Production of Tumor Necrosis Factor-Alpha in BV2 Microglial Cells
- Growth related secretion and production of GM-CSF by epithelial cell line
- Harpagophytum procumbens Suppresses Lipopolysaccharide-Stimulated Expressions of Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in Fibroblast Cell Line L929
- Phase Formation and Electrical Conductivity of Ba-Doped LaScO_3
- Electrical Conduction Behavior of Layered Perovskite La_Ba_GaO_
- Martensitic Transformation and Superelasticity of Ti-Nb-Pt Alloys
- Protective Effect of Gabapentin on N-Methyl-D-aspartate-Induced Excitotoxicity in Rat Hippocampal CA1 Neurons
- Effect of postnatal treadmill exercise on c-Fos expression in the hippocampus of rat pups born from the alcohol-intoxicated mothers
- Maternal swimming during pregnancy enhances short-term memory and neurogenesis in the hippocampus of rat pups
- Influence of prenatal noise and music on the spatial memory and neurogenesis in the hippocampus of developing rats
- Low-Cell-Gap Measurement by Rotation of a Wave Retarder(Instrumentation, Measurement, and Fabrication Technology)
- A New Design of Optical Configuration of Taansflective Liquid Crystal Displays using Antiferroelectric Liquid Crystals and Frustelectric Ferroelectric Liquid Crystals : Instrumentation, Measurement, and Fabrication Technology
- Reflective Liquid Crystal Display Using a Non-Twist Half-Wave Cell
- Efficacy and outcome of anterior vaginal wall repair using polypropylene mesh (Gynemesh)
- Methylation status of mage gene famaily and cage1 promoters in squamous cell carcinoma of uterine cervix(Oncology 4)
- Polymorphisms of interleukin (IL)-1β and IL-4R and the risk of ovarian cancer(Oncology 2)
- ERCC1 polymorphism : a predictive factor of resistance to first-line platinum-based chemotherapy in epithelial ovarian cancer(Oncology 1)
- Inhibitory Effect of Poncirus trifoliate on Acetylcholinesterase and Attenuating Activity against Trimethyltin-Induced Learning and Memory Impairment
- Daidzein Activates Choline Acetyltransferase from MC-IXC Cells and Improves Drug-Induced Amnesia
- Effects of Oleamide on Choline Acetyltransferase and Cognitive Activities(Food & Nutrition Science)
- Preservative Effect of Electrolyzed Reduced Water on Pancreatic β-Cell Mass in Diabetic db/db Mice(Biochemistry)
- Dissimilarity in Fos and Jun Immunoreactivity in Hypothalamic Regions between Obese and Lean Zucker Rats
- Inhibitory Effects of Egg Yolk Soluble Protein on Bone Resorption
- Effects of Egg Yolk Proteins on the Longitudinal Bone Growth of Adolescent Male Rats
- Protective Effect of Methanol Extract of Uncaria rhynchophylla Against Excitotoxicity Induced by N-Methyl-D-Aspartate in Rat Hippocampus
- 頚椎に発生した浸潤性脂肪腫の犬の1例(外科学)
- Red Ginseng Inhibits Exercise-Induced Increase in 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in Dorsal Raphe of Rats
- Cell Cycle Inhibitory Activity of 4-Hydroxy-3-(3'-methyl-2'-butenyl)-benzoic Acid from Curvularia sp. KF119
- Improvement of Diabetic Complication by Hydrangea Dulcis Folium in Streptozotocin-Induced Diabetic Rats(Miscellaneous)
- Protective Effects of Aucubin Isolated from Eucommia ulmoides against UVB-Induced Oxidative Stress in Human Skin Fibroblasts(Pharmacognosy)
- Amygdalin Induces Apoptosis through Regulation of Bax and Bcl-2 Expressions in Human DU145 and LNCaP Prostate Cancer Cells(Pharmacology)
- Modulation of Corydalis tuber on Glycine-Induced Ion Current in Acutely Dissociated Rat Periaqueductal Gray Neurons(Pharmacology)
- Antinociceptive Effect of Amygdalin Isolated from Prunus armeniaca on Formalin-Induced Pain in Rats(Pharmacognosy)
- Effect of Ginseng radix on c-Fos Expression in the Hippocampus of Streptozotocin-Induced Diabetic Rats
- Abdominal compartment syndrome occurring due to uterine perforation during a hysteroscopy procedure
- Activation Effects of Allium Tuberosum Rottl. on Choline Acetyltransferase
- Effects of Green Tea Polyphenol on Cognitive and Acetylcholinesterase Activities
- Ameliorative Effects of Soy 11S Protein on Liver Damage and Hyperlipidemia in Alcohol-Fed Rats(Biopharmacy)
- Egg Yolk Soluble Protein Stimulates the Proliferation and Differentiation of Osteoblastic MC3T3-E1 Cells
- Complications in Motility Peg Placement for Hydroxyapatite Orbital Implant in Anophthalmic Socket
- Clinical Characteristics of Obese Japanese Children with Acanthosis Nigricans
- IS-46 Validation of the Revised 2009 FIGO Staging System for Endometrial Cancer : a Multi-center Study(Group6 Oncology6,International Session)
- Biotin-Avidin Mediated Homogeneous Enzyme-Linked Binding Assays for Riboflavin and Riboflavin Binding Protein Using Alkaline Phosphatase as the Label
- Effect of Etch Gas on Dry Etching of Ferroelectric Bi_La_Ti_3O_ Thin Films
- Protective Effects of Kaempferol (3,4′,5,7-tetrahydroxyflavone) against Amyloid Beta Peptide (Aβ)-Induced Neurotoxicity in ICR Mice
- Activation Effects of Allium Tuberosum Rottl. on Choline Acetyltransferase
- Effect of Vitamin E Supplementation on Antioxidant Defense Systems and Humoral Immune Responses in Young, Middle-Aged and Elderly Korean Women
- The Suppressive Effect of β-Glucan on the Production of Tumor Necrosis Factor-Alpha in BV2 Microglial Cells
- Egg Yolk Soluble Protein Stimulates the Proliferation and Differentiation of Osteoblastic MC3T3-E1 Cells
- Protective Effects of Kaempferol (3,4',5,7-tetrahydroxyflavone) against Amyloid Beta Peptide (Aβ)-Induced Neurotoxicity in ICR Mice
- Inhibitory Effect of Poncirus trifoliate on Acetylcholinesterase and Attenuating Activity against Trimethyltin-Induced Learning and Memory Impairment
- Inhibitory Effects of Egg Yolk Soluble Protein on Bone Resorption
- Zeatin Supplement Improves Scopolamine-Induced Memory Impairment in Mice
- Ferulic Acid Supplementation Prevents Trimethyltin-Induced Cognitive Deficits in Mice
- Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups